Target	Common name	Uniprot ID	ChEMBL ID	Target Class	Probability*	Known actives (3D/2D)
Glutamate NMDA receptor; GRIN1/GRIN2B	N/A	Q05586&Q13224	CHEMBL1907603	Ligand-gated ion channel	0.8320331767939197	1184 / 31
Glutamate NMDA receptor; GRIN1/GRIN2A	N/A	Q05586&Q12879	CHEMBL1907604	Ligand-gated ion channel	0.8139033219942098	133 / 15
Mu-type opioid receptor	OPRM1	P35372	CHEMBL233	Family A G protein-coupled receptor	0.7716879761363552	3430 / 1687
Sigma non-opioid intracellular receptor 1	SIGMAR1	Q99720	CHEMBL287	Membrane receptor	0.7675312096548441	2443 / 892
Sodium-dependent dopamine transporter	SLC6A3	Q01959	CHEMBL238	Electrochemical transporter	0.7445640988691914	2781 / 1304
Sodium-dependent serotonin transporter	SLC6A4	P31645	CHEMBL228	Electrochemical transporter	0.7445640988691914	4229 / 1632
Sodium-dependent noradrenaline transporter	SLC6A2	P23975	CHEMBL222	Electrochemical transporter	0.7034519171484501	3017 / 1242
Sigma intracellular receptor 2	TMEM97	Q5BJF2	CHEMBL4105907	Membrane receptor	0.6933106260359395	508 / 158
Nociceptin receptor	OPRL1	P41146	CHEMBL2014	Family A G protein-coupled receptor	0.691810399857713	1978 / 991
Kappa-type opioid receptor	OPRK1	P41145	CHEMBL237	Family A G protein-coupled receptor	0.6679637464567434	2509 / 718
Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2	Q12809	CHEMBL240	Voltage-gated ion channel	0.6298232723839499	3973 / 507
Lysosomal Pro-X carboxypeptidase	PRCP	P42785	CHEMBL2335	Protease	0.6170919877681964	308 / 73
Alpha-2B adrenergic receptor	ADRA2B	P18089	CHEMBL1942	Family A G protein-coupled receptor	0.5547060264012582	380 / 33
5-hydroxytryptamine receptor 2B	HTR2B	P41595	CHEMBL1833	Family A G protein-coupled receptor	0.4663205170466411	1027 / 123
Cytochrome P450 2C19	CYP2C19	P33261	CHEMBL3622	Cytochrome P450	0.4663205170466411	82 / 12
Amine oxidase [flavin-containing] A	MAOA	P21397	CHEMBL1951	Oxidoreductase	0.4375229173805658	843 / 125
D(2) dopamine receptor	DRD2	P14416	CHEMBL217	Family A G protein-coupled receptor	0.41424986829775645	4858 / 693
Lysine-specific histone demethylase 1A	KDM1A	O60341	CHEMBL6136	Eraser	0.4056309133966344	2236 / 457
D(3) dopamine receptor	DRD3	P35462	CHEMBL234	Family A G protein-coupled receptor	0.39425902652047395	2984 / 435
Neuronal acetylcholine receptor; alpha4/beta2	N/A	P17787&P43681	CHEMBL1907589	Ligand-gated ion channel	0.39004756799921436	668 / 73
Neuronal acetylcholine receptor subunit alpha-7	CHRNA7	P36544	CHEMBL2492	Ligand-gated ion channel	0.3338140755324319	895 / 71
Neuronal acetylcholine receptor; alpha3/beta4	N/A	P30926&P32297	CHEMBL1907594	Ligand-gated ion channel	0.3338140755324319	330 / 43
Amine oxidase [flavin-containing] B	MAOB	P27338	CHEMBL2039	Oxidoreductase	0.33093470020973786	1616 / 168
D(4) dopamine receptor	DRD4	P21917	CHEMBL219	Family A G protein-coupled receptor	0.3160675114554422	1821 / 312
C-X-C chemokine receptor type 4	CXCR4	P61073	CHEMBL2107	Family A G protein-coupled receptor	0.3135932074154565	191 / 35
5-hydroxytryptamine receptor 2A	HTR2A	P28223	CHEMBL224	Family A G protein-coupled receptor	0.30970337648889795	3558 / 313
Carbonic anhydrase 1	CA1	P00915	CHEMBL261	Lyase	0.30834711619400246	3346 / 41
Histamine H3 receptor	HRH3	Q9Y5N1	CHEMBL264	Family A G protein-coupled receptor	0.30752434023155933	2286 / 380
Melanocortin receptor 5	MC5R	P33032	CHEMBL4608	Family A G protein-coupled receptor	0.3063853921899314	218 / 56
5-hydroxytryptamine receptor 2C	HTR2C	P28335	CHEMBL225	Family A G protein-coupled receptor	0.3063853921899314	2332 / 201
Alpha-2C adrenergic receptor	ADRA2C	P18825	CHEMBL1916	Family A G protein-coupled receptor	0.3063853921899314	442 / 45
Muscarinic acetylcholine receptor M1	CHRM1	P11229	CHEMBL216	Family A G protein-coupled receptor	0.3063853921899314	1133 / 175
Alpha-2A adrenergic receptor	ADRA2A	P08913	CHEMBL1867	Family A G protein-coupled receptor	0.3063853921899314	582 / 55
Muscarinic acetylcholine receptor M5	CHRM5	P08912	CHEMBL2035	Family A G protein-coupled receptor	0.3063853921899314	414 / 79
Muscarinic acetylcholine receptor M4	CHRM4	P08173	CHEMBL1821	Family A G protein-coupled receptor	0.3063853921899314	635 / 113
Muscarinic acetylcholine receptor M2	CHRM2	P08172	CHEMBL211	Family A G protein-coupled receptor	0.3063853921899314	1053 / 236
Substance-P receptor	TACR1	P25103	CHEMBL249	Family A G protein-coupled receptor	0.2912202763035897	1769 / 470
Carbonic anhydrase 2	CA2	P00918	CHEMBL205	Lyase	0.28998690945409855	4028 / 40
Cholinesterase	BCHE	P06276	CHEMBL1914	Hydrolase	0.28594477082990055	1400 / 185
Glutamate receptor ionotropic, NMDA 2B	GRIN2B	Q13224	CHEMBL1904	Ligand-gated ion channel	0.2639933428179119	1242 / 148
Dipeptidyl peptidase 4	DPP4	P27487	CHEMBL284	Protease	0.24279382824632098	3032 / 194
P2X purinoceptor 7	P2RX7	Q99572	CHEMBL4805	Ligand-gated ion channel	0.2420890915662631	3461 / 395
Delta-type opioid receptor	OPRD1	P41143	CHEMBL236	Family A G protein-coupled receptor	0.24111233900219992	1438 / 856
LSD1/CoREST complex	N/A	O60341&Q9UKL0	CHEMBL3137262	Eraser	0.23929392096781885	83 / 41
Beta-2 adrenergic receptor	ADRB2	P07550	CHEMBL210	Family A G protein-coupled receptor	0.23693616416239074	259 / 17
Acetylcholinesterase	ACHE	P22303	CHEMBL220	Hydrolase	0.22317773254042625	2287 / 356
Nischarin	NISCH	Q9Y2I1	CHEMBL3923	Other cytosolic protein	0.2104492643126719	131 / 9
Kinesin-like protein KIF11	KIF11	P52732	CHEMBL4581	Other cytosolic protein	0.2071391437959113	541 / 35
Cannabinoid receptor 1	CNR1	P21554	CHEMBL218	Family A G protein-coupled receptor	0.20349474717200508	2356 / 191
C-C chemokine receptor type 3	CCR3	P51677	CHEMBL3473	Family A G protein-coupled receptor	0.20189652518508935	639 / 124
Mitogen-activated protein kinase 14	MAPK14	Q16539	CHEMBL260	Kinase	0.20014047710429128	2491 / 12
C-X-C chemokine receptor type 3	CXCR3	P49682	CHEMBL4441	Family A G protein-coupled receptor	0.19885582059769918	620 / 145
5-hydroxytryptamine receptor 1A	HTR1A	P08908	CHEMBL214	Family A G protein-coupled receptor	0.19564993340323536	3436 / 323
D(1B) dopamine receptor	DRD5	P21918	CHEMBL1850	Family A G protein-coupled receptor	0.19130466856455405	154 / 46
D(1A) dopamine receptor	DRD1	P21728	CHEMBL2056	Family A G protein-coupled receptor	0.19130466856455405	548 / 119
Histamine H1 receptor	HRH1	P35367	CHEMBL231	Family A G protein-coupled receptor	0.18369081845667595	762 / 107
Histamine H2 receptor	HRH2	P25021	CHEMBL1941	Family A G protein-coupled receptor	0.1715673635726912	244 / 34
Phenylethanolamine N-methyltransferase	PNMT	P11086	CHEMBL4617	Transferase	0.17041930386288234	136 / 59
Nitric oxide synthase 1	NOS1	P29475	CHEMBL3568	Oxidoreductase	0.15621468132234298	762 / 45
Lysine-specific demethylase 2B	KDM2B	Q8NHM5	CHEMBL3779760	Eraser	0.1557840451545251	336 / 188
Lanosterol synthase	LSS	P48449	CHEMBL3593	Isomerase	0.15565729966896344	78 / 9
Muscarinic acetylcholine receptor M3	CHRM3	P20309	CHEMBL245	Family A G protein-coupled receptor	0.1456542478962006	1294 / 193
Beta-secretase 1	BACE1	P56817	CHEMBL4822	Protease	0.14078079373728106	5654 / 143
Monoglyceride lipase	MGLL	Q99685	CHEMBL4191	Hydrolase	0.13939363009897193	1064 / 164
Cytochrome P450 2C9	CYP2C9	P11712	CHEMBL3397	Cytochrome P450	0.13928112478551571	77 / 7
Alpha-1B adrenergic receptor	ADRA1B	P35368	CHEMBL232	Family A G protein-coupled receptor	0.13849024520186648	585 / 34
Indoleamine 2,3-dioxygenase 1	IDO1	P14902	CHEMBL4685	Oxidoreductase	0.13709832448559262	1846 / 89
Melanocortin receptor 4	MC4R	P32245	CHEMBL259	Family A G protein-coupled receptor	0.13039298580006295	1393 / 394
11-beta-hydroxysteroid dehydrogenase 1	HSD11B1	P28845	CHEMBL4235	Oxidoreductase	0.12796755646007615	2183 / 503
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	EBP	Q15125	CHEMBL4931	Isomerase	0.12252018237444384	54 / 17
5-hydroxytryptamine receptor 6	HTR6	P50406	CHEMBL3371	Family A G protein-coupled receptor	0.12194971331012074	3172 / 59
Sodium channel protein type 2 subunit alpha	SCN2A	Q99250	CHEMBL4187	Voltage-gated ion channel	0.12133071144913767	75 / 12
Sodium channel protein type 5 subunit alpha	SCN5A	Q14524	CHEMBL1980	Voltage-gated ion channel	0.12133071144913767	349 / 19
Sodium channel protein type 9 subunit alpha	SCN9A	Q15858	CHEMBL4296	Voltage-gated ion channel	0.11965570080319649	3731 / 34
Androgen receptor	AR	P10275	CHEMBL1871	Nuclear receptor	0.11807032415619832	1384 / 53
Sodium- and chloride-dependent glycine transporter 1	SLC6A9	P48067	CHEMBL2337	Electrochemical transporter	0.11763236068657311	737 / 163
Synaptic vesicular amine transporter	SLC18A2	Q05940	CHEMBL1893	Electrochemical transporter	0.11524688310109844	41 / 13
cGMP-dependent 3',5'-cyclic phosphodiesterase	PDE2A	O00408	CHEMBL2652	Phosphodiesterase	0.11517005255495463	1500 / 8
5-hydroxytryptamine receptor 7	HTR7	P34969	CHEMBL3155	Family A G protein-coupled receptor	0.109330632983895	2178 / 152
Bifunctional epoxide hydrolase 2	EPHX2	P34913	CHEMBL2409	Protease	0.10789554740592924	1269 / 239
Alpha-1D adrenergic receptor	ADRA1D	P25100	CHEMBL223	Family A G protein-coupled receptor	0.10522009273691832	536 / 31
Epoxide hydrolase 1	EPHX1	P07099	CHEMBL1968	Protease	0.10290035868516101	192 / 35
Transient receptor potential cation channel subfamily V member 1	TRPV1	Q8NER1	CHEMBL4794	Voltage-gated ion channel	0.1002971646562749	1480 / 47
5-hydroxytryptamine receptor 5A	HTR5A	P47898	CHEMBL3426	Family A G protein-coupled receptor	0.09860881553886527	281 / 20
Cathepsin S	CTSS	P25774	CHEMBL2954	Protease	0.09758337448370295	1317 / 63
Cannabinoid receptor 2	CNR2	P34972	CHEMBL253	Family A G protein-coupled receptor	0.09659261072156482	2921 / 239
Sphingosine kinase 2	SPHK2	Q9NRA0	CHEMBL3023	Enzyme	0.09571053406626011	87 / 27
Voltage-dependent T-type calcium channel subunit alpha-1G	CACNA1G	O43497	CHEMBL4641	Voltage-gated ion channel	0.09559128695985603	316 / 54
Estrogen receptor	ESR1	P03372	CHEMBL206	Nuclear receptor	0.09410014518962387	325 / 52
Cytochrome P450 3A4	CYP3A4	P08684	CHEMBL340	Cytochrome P450	0.09361760526323731	172 / 31
Acyl-CoA (8-3)-desaturase	FADS1	O60427	CHEMBL5840	Enzyme	0.0929020673127819	21 / 1
Cytochrome P450 2D6	CYP2D6	P10635	CHEMBL289	Cytochrome P450	0.09245023910802352	221 / 68
Transient receptor potential cation channel subfamily A member 1	TRPA1	O75762	CHEMBL6007	Voltage-gated ion channel	0.09209394873963665	611 / 43
Sphingosine 1-phosphate receptor 3	S1PR3	Q99500	CHEMBL3892	Family A G protein-coupled receptor	0.09024136094692237	519 / 43
3-phosphoinositide-dependent protein kinase 1	PDPK1	O15530	CHEMBL2534	Kinase	0.09021885334702753	427 / 2
Intermediate conductance calcium-activated potassium channel protein 4	KCNN4	O15554	CHEMBL4305	Voltage-gated ion channel	0.08861600389840009	111 / 10
Vesicular acetylcholine transporter	SLC18A3	Q16572	CHEMBL4767	Electrochemical transporter	0.08218675784764094	181 / 96
Cathepsin K	CTSK	P43235	CHEMBL268	Protease	0.08132767483514561	1179 / 102
RAC-alpha serine/threonine-protein kinase	AKT1	P31749	CHEMBL4282	Kinase	0.08116571085057281	2269 / 39
Cyclin-dependent kinase 8	CDK8	P49336	CHEMBL5719	Kinase	0.07924464915426656	291 / 22

*Probability for the query molecule - assumed as bioactive - to have this protein as target.