Target	Common name	Uniprot ID	ChEMBL ID	Target Class	Probability*	Known actives (3D/2D)
Glutamate NMDA receptor; GRIN1/GRIN2B	N/A	Q05586&Q13224	CHEMBL1907603	Ligand-gated ion channel	0.8251133925994554	1080 / 31
Glutamate NMDA receptor; GRIN1/GRIN2A	N/A	Q05586&Q12879	CHEMBL1907604	Ligand-gated ion channel	0.8251133925994554	120 / 15
Sigma non-opioid intracellular receptor 1	SIGMAR1	Q99720	CHEMBL287	Membrane receptor	0.7765866624283628	2426 / 892
Sodium-dependent dopamine transporter	SLC6A3	Q01959	CHEMBL238	Electrochemical transporter	0.7425179450448014	2764 / 1304
Sodium-dependent serotonin transporter	SLC6A4	P31645	CHEMBL228	Electrochemical transporter	0.7425179450448014	4212 / 1632
Sodium-dependent noradrenaline transporter	SLC6A2	P23975	CHEMBL222	Electrochemical transporter	0.7046441392978442	3008 / 1242
Mu-type opioid receptor	OPRM1	P35372	CHEMBL233	Family A G protein-coupled receptor	0.70218092944635	3327 / 1687
Nociceptin receptor	OPRL1	P41146	CHEMBL2014	Family A G protein-coupled receptor	0.6619180427136198	1887 / 991
Sigma intracellular receptor 2	TMEM97	Q5BJF2	CHEMBL4105907	Membrane receptor	0.6606854470684909	497 / 158
Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2	Q12809	CHEMBL240	Voltage-gated ion channel	0.6230500184859266	3816 / 507
Lysosomal Pro-X carboxypeptidase	PRCP	P42785	CHEMBL2335	Protease	0.6115119685932767	305 / 73
Kappa-type opioid receptor	OPRK1	P41145	CHEMBL237	Family A G protein-coupled receptor	0.5903366323692899	2463 / 718
Alpha-2B adrenergic receptor	ADRA2B	P18089	CHEMBL1942	Family A G protein-coupled receptor	0.49621634014922295	373 / 33
D(3) dopamine receptor	DRD3	P35462	CHEMBL234	Family A G protein-coupled receptor	0.4279874919549297	2894 / 435
D(2) dopamine receptor	DRD2	P14416	CHEMBL217	Family A G protein-coupled receptor	0.4279874919549297	4742 / 693
5-hydroxytryptamine receptor 2B	HTR2B	P41595	CHEMBL1833	Family A G protein-coupled receptor	0.41545885086809814	1015 / 123
Cytochrome P450 2C19	CYP2C19	P33261	CHEMBL3622	Cytochrome P450	0.41545885086809814	78 / 12
Neuronal acetylcholine receptor subunit alpha-7	CHRNA7	P36544	CHEMBL2492	Ligand-gated ion channel	0.39625481572138777	888 / 71
Neuronal acetylcholine receptor; alpha3/beta4	N/A	P30926&P32297	CHEMBL1907594	Ligand-gated ion channel	0.39625481572138777	328 / 43
Neuronal acetylcholine receptor; alpha4/beta2	N/A	P17787&P43681	CHEMBL1907589	Ligand-gated ion channel	0.39625481572138777	676 / 73
Lysine-specific histone demethylase 1A	KDM1A	O60341	CHEMBL6136	Eraser	0.39602505148830225	2196 / 457
Amine oxidase [flavin-containing] B	MAOB	P27338	CHEMBL2039	Oxidoreductase	0.3740834013500194	1560 / 168
Amine oxidase [flavin-containing] A	MAOA	P21397	CHEMBL1951	Oxidoreductase	0.35762613855689035	813 / 125
Histamine H3 receptor	HRH3	Q9Y5N1	CHEMBL264	Family A G protein-coupled receptor	0.32840324064828197	2213 / 380
Carbonic anhydrase 1	CA1	P00915	CHEMBL261	Lyase	0.32199518223703416	3155 / 41
D(4) dopamine receptor	DRD4	P21917	CHEMBL219	Family A G protein-coupled receptor	0.3126964160814252	1803 / 312
C-X-C chemokine receptor type 4	CXCR4	P61073	CHEMBL2107	Family A G protein-coupled receptor	0.3114101006937001	190 / 35
Carbonic anhydrase 2	CA2	P00918	CHEMBL205	Lyase	0.3046581498049416	3801 / 40
5-hydroxytryptamine receptor 2A	HTR2A	P28223	CHEMBL224	Family A G protein-coupled receptor	0.3045926739119127	3492 / 313
Substance-P receptor	TACR1	P25103	CHEMBL249	Family A G protein-coupled receptor	0.29952229768624944	1678 / 470
5-hydroxytryptamine receptor 2C	HTR2C	P28335	CHEMBL225	Family A G protein-coupled receptor	0.2949048554256871	2293 / 201
Muscarinic acetylcholine receptor M5	CHRM5	P08912	CHEMBL2035	Family A G protein-coupled receptor	0.2885469316444282	403 / 79
Melanocortin receptor 5	MC5R	P33032	CHEMBL4608	Family A G protein-coupled receptor	0.27505518160227055	210 / 56
Alpha-2C adrenergic receptor	ADRA2C	P18825	CHEMBL1916	Family A G protein-coupled receptor	0.27505518160227055	436 / 45
Muscarinic acetylcholine receptor M1	CHRM1	P11229	CHEMBL216	Family A G protein-coupled receptor	0.27505518160227055	1112 / 175
Alpha-2A adrenergic receptor	ADRA2A	P08913	CHEMBL1867	Family A G protein-coupled receptor	0.27505518160227055	572 / 55
Muscarinic acetylcholine receptor M4	CHRM4	P08173	CHEMBL1821	Family A G protein-coupled receptor	0.27505518160227055	619 / 113
Muscarinic acetylcholine receptor M2	CHRM2	P08172	CHEMBL211	Family A G protein-coupled receptor	0.27505518160227055	1029 / 236
Delta-type opioid receptor	OPRD1	P41143	CHEMBL236	Family A G protein-coupled receptor	0.24997974035545384	1415 / 856
Phenylethanolamine N-methyltransferase	PNMT	P11086	CHEMBL4617	Transferase	0.2479696928123027	136 / 59
Nischarin	NISCH	Q9Y2I1	CHEMBL3923	Other cytosolic protein	0.24275760574423857	135 / 9
Dipeptidyl peptidase 4	DPP4	P27487	CHEMBL284	Protease	0.24238579594939164	2985 / 194
Cholinesterase	BCHE	P06276	CHEMBL1914	Hydrolase	0.24108051228934946	1336 / 185
Acetylcholinesterase	ACHE	P22303	CHEMBL220	Hydrolase	0.2373471278962039	2172 / 356
P2X purinoceptor 7	P2RX7	Q99572	CHEMBL4805	Ligand-gated ion channel	0.22673375924656602	3341 / 395
Cannabinoid receptor 1	CNR1	P21554	CHEMBL218	Family A G protein-coupled receptor	0.22670374815538236	2150 / 191
Beta-2 adrenergic receptor	ADRB2	P07550	CHEMBL210	Family A G protein-coupled receptor	0.22065835955307153	247 / 17
LSD1/CoREST complex	N/A	O60341&Q9UKL0	CHEMBL3137262	Eraser	0.21429157283619898	80 / 41
Glutamate receptor ionotropic, NMDA 2B	GRIN2B	Q13224	CHEMBL1904	Ligand-gated ion channel	0.21145395348676252	1176 / 148
Histamine H1 receptor	HRH1	P35367	CHEMBL231	Family A G protein-coupled receptor	0.20154909510762878	749 / 107
D(1B) dopamine receptor	DRD5	P21918	CHEMBL1850	Family A G protein-coupled receptor	0.19722604992032478	151 / 46
D(1A) dopamine receptor	DRD1	P21728	CHEMBL2056	Family A G protein-coupled receptor	0.19722604992032478	533 / 119
Mitogen-activated protein kinase 14	MAPK14	Q16539	CHEMBL260	Kinase	0.1862036442239172	2326 / 12
C-C chemokine receptor type 3	CCR3	P51677	CHEMBL3473	Family A G protein-coupled receptor	0.1840707838073158	629 / 124
Nitric oxide synthase 1	NOS1	P29475	CHEMBL3568	Oxidoreductase	0.18382672228698213	766 / 45
C-X-C chemokine receptor type 3	CXCR3	P49682	CHEMBL4441	Family A G protein-coupled receptor	0.18180786172187202	591 / 145
Lanosterol synthase	LSS	P48449	CHEMBL3593	Isomerase	0.17488874027733084	72 / 9
5-hydroxytryptamine receptor 1A	HTR1A	P08908	CHEMBL214	Family A G protein-coupled receptor	0.17273027431682025	3393 / 323
Lysine-specific demethylase 2B	KDM2B	Q8NHM5	CHEMBL3779760	Eraser	0.17107753871566964	338 / 188
Histamine H2 receptor	HRH2	P25021	CHEMBL1941	Family A G protein-coupled receptor	0.1662338929008337	237 / 34
Synaptic vesicular amine transporter	SLC18A2	Q05940	CHEMBL1893	Electrochemical transporter	0.16160620038185755	42 / 13
Kinesin-like protein KIF11	KIF11	P52732	CHEMBL4581	Other cytosolic protein	0.15997569187804614	536 / 35
Beta-secretase 1	BACE1	P56817	CHEMBL4822	Protease	0.15978867690990914	5408 / 143
Alpha-1B adrenergic receptor	ADRA1B	P35368	CHEMBL232	Family A G protein-coupled receptor	0.15320574191128028	563 / 34
Melanocortin receptor 4	MC4R	P32245	CHEMBL259	Family A G protein-coupled receptor	0.1529881896653232	1367 / 394
Cytochrome P450 2C9	CYP2C9	P11712	CHEMBL3397	Cytochrome P450	0.15239815216795372	72 / 7
Indoleamine 2,3-dioxygenase 1	IDO1	P14902	CHEMBL4685	Oxidoreductase	0.15065042540221793	1651 / 89
11-beta-hydroxysteroid dehydrogenase 1	HSD11B1	P28845	CHEMBL4235	Oxidoreductase	0.15016713255581393	2028 / 503
Monoglyceride lipase	MGLL	Q99685	CHEMBL4191	Hydrolase	0.14903222114977097	1013 / 164
5-hydroxytryptamine receptor 6	HTR6	P50406	CHEMBL3371	Family A G protein-coupled receptor	0.1372623576301433	3147 / 59
Androgen receptor	AR	P10275	CHEMBL1871	Nuclear receptor	0.13617056486256596	1247 / 53
Muscarinic acetylcholine receptor M3	CHRM3	P20309	CHEMBL245	Family A G protein-coupled receptor	0.13461811618537972	1268 / 193
Alpha-1D adrenergic receptor	ADRA1D	P25100	CHEMBL223	Family A G protein-coupled receptor	0.13152561616276776	523 / 31
cGMP-dependent 3',5'-cyclic phosphodiesterase	PDE2A	O00408	CHEMBL2652	Phosphodiesterase	0.12767707452339616	1404 / 8
5-hydroxytryptamine receptor 7	HTR7	P34969	CHEMBL3155	Family A G protein-coupled receptor	0.12574457673189143	2159 / 152
3-phosphoinositide-dependent protein kinase 1	PDPK1	O15530	CHEMBL2534	Kinase	0.1250937497964455	397 / 2
Sodium- and chloride-dependent glycine transporter 1	SLC6A9	P48067	CHEMBL2337	Electrochemical transporter	0.12395307304217099	724 / 163
Bifunctional epoxide hydrolase 2	EPHX2	P34913	CHEMBL2409	Protease	0.11621107820445091	1159 / 239
Sodium channel protein type 2 subunit alpha	SCN2A	Q99250	CHEMBL4187	Voltage-gated ion channel	0.11616403728207442	71 / 12
Sodium channel protein type 5 subunit alpha	SCN5A	Q14524	CHEMBL1980	Voltage-gated ion channel	0.11355706265742203	333 / 19
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	EBP	Q15125	CHEMBL4931	Isomerase	0.11349947661137233	53 / 17
Sodium channel protein type 9 subunit alpha	SCN9A	Q15858	CHEMBL4296	Voltage-gated ion channel	0.11261274844168835	3454 / 34
Epoxide hydrolase 1	EPHX1	P07099	CHEMBL1968	Protease	0.10997230526002277	167 / 35
Sphingosine kinase 2	SPHK2	Q9NRA0	CHEMBL3023	Enzyme	0.10992144097487283	81 / 27
Estrogen receptor	ESR1	P03372	CHEMBL206	Nuclear receptor	0.10991494131467593	302 / 52
5-hydroxytryptamine receptor 1D	HTR1D	P28221	CHEMBL1983	Family A G protein-coupled receptor	0.10945933984215434	829 / 52
Acyl-CoA (8-3)-desaturase	FADS1	O60427	CHEMBL5840	Enzyme	0.10918912492284921	21 / 1
5-hydroxytryptamine receptor 5A	HTR5A	P47898	CHEMBL3426	Family A G protein-coupled receptor	0.10714025160252634	277 / 20
Cannabinoid receptor 2	CNR2	P34972	CHEMBL253	Family A G protein-coupled receptor	0.10678321416210461	2620 / 239
Transient receptor potential cation channel subfamily A member 1	TRPA1	O75762	CHEMBL6007	Voltage-gated ion channel	0.10669656155952378	517 / 43
Voltage-dependent T-type calcium channel subunit alpha-1G	CACNA1G	O43497	CHEMBL4641	Voltage-gated ion channel	0.10568864310895719	294 / 54
Cytochrome P450 2D6	CYP2D6	P10635	CHEMBL289	Cytochrome P450	0.10514718571400067	218 / 68
Transient receptor potential cation channel subfamily V member 1	TRPV1	Q8NER1	CHEMBL4794	Voltage-gated ion channel	0.10409769407035739	1299 / 47
Nitric oxide synthase, inducible	NOS2	P35228	CHEMBL4481	Enzyme	0.102353130326231	467 / 47
Vesicular acetylcholine transporter	SLC18A3	Q16572	CHEMBL4767	Electrochemical transporter	0.10089785754245421	179 / 96
Cytochrome P450 3A4	CYP3A4	P08684	CHEMBL340	Cytochrome P450	0.0992566841094912	166 / 31
Sphingosine 1-phosphate receptor 3	S1PR3	Q99500	CHEMBL3892	Family A G protein-coupled receptor	0.0935935961695126	433 / 43
Cathepsin K	CTSK	P43235	CHEMBL268	Protease	0.09209141997052635	1095 / 102
RAC-alpha serine/threonine-protein kinase	AKT1	P31749	CHEMBL4282	Kinase	0.09194114986336928	2187 / 39
Cathepsin S	CTSS	P25774	CHEMBL2954	Protease	0.0910184266767024	1212 / 63

*Probability for the query molecule - assumed as bioactive - to have this protein as target.