Target	Common name	Uniprot ID	ChEMBL ID	Target Class	Probability*	Known actives (3D/2D)
Sigma non-opioid intracellular receptor 1	SIGMAR1	Q99720	CHEMBL287	Membrane receptor	0.9813916872922418	2313 / 58
Acetylcholinesterase	ACHE	P22303	CHEMBL220	Hydrolase	0.9667989468231868	1865 / 12
Histamine H3 receptor	HRH3	Q9Y5N1	CHEMBL264	Family A G protein-coupled receptor	0.9598664107469997	1775 / 7
Neuronal acetylcholine receptor; alpha4/beta2	N/A	P17787&P43681	CHEMBL1907589	Ligand-gated ion channel	0.9529017855778075	569 / 27
Neuronal acetylcholine receptor; alpha3/beta4	N/A	P30926&P32297	CHEMBL1907594	Ligand-gated ion channel	0.9483303781975342	279 / 14
Neuronal acetylcholine receptor subunit alpha-7	CHRNA7	P36544	CHEMBL2492	Ligand-gated ion channel	0.9430669072688896	781 / 9
Neuronal acetylcholine receptor; alpha2/beta4	N/A	P30926&Q15822	CHEMBL2109230	Ligand-gated ion channel	0.9399610892401211	9 / 1
Neuronal acetylcholine receptor; alpha3/beta2	N/A	P17787&P32297	CHEMBL2109234	Ligand-gated ion channel	0.9396710054083782	41 / 1
Cholinesterase	BCHE	P06276	CHEMBL1914	Hydrolase	0.9296680274839791	1197 / 17
Acetylcholine receptor; alpha1/beta1/delta/gamma	N/A	P02708&P07510&P11230&Q07001	CHEMBL1907588	Ligand-gated ion channel	0.9296680274839791	17 / 2
UDP-glucuronosyltransferase 2B7	UGT2B7	P16662	CHEMBL4370	Transferase	0.8742243438244396	12 / 1
Sodium-dependent noradrenaline transporter	SLC6A2	P23975	CHEMBL222	Electrochemical transporter	0.8261987859287113	2777 / 22
Muscarinic acetylcholine receptor M1	CHRM1	P11229	CHEMBL216	Family A G protein-coupled receptor	0.818710743379651	1040 / 21
Muscarinic acetylcholine receptor M5	CHRM5	P08912	CHEMBL2035	Family A G protein-coupled receptor	0.818710743379651	372 / 9
Muscarinic acetylcholine receptor M4	CHRM4	P08173	CHEMBL1821	Family A G protein-coupled receptor	0.818710743379651	583 / 9
Muscarinic acetylcholine receptor M2	CHRM2	P08172	CHEMBL211	Family A G protein-coupled receptor	0.818710743379651	961 / 21
Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2	Q12809	CHEMBL240	Voltage-gated ion channel	0.8148735536247569	3293 / 5
Dynamin-1	DNM1	Q05193	CHEMBL4958	Hydrolase	0.8125627683285783	21 / 11
Muscarinic acetylcholine receptor M3	CHRM3	P20309	CHEMBL245	Family A G protein-coupled receptor	0.7896814853645129	1144 / 5
Alpha-2C adrenergic receptor	ADRA2C	P18825	CHEMBL1916	Family A G protein-coupled receptor	0.7896814853645129	405 / 7
Alpha-2B adrenergic receptor	ADRA2B	P18089	CHEMBL1942	Family A G protein-coupled receptor	0.7298951215579784	344 / 5
Sodium-dependent dopamine transporter	SLC6A3	Q01959	CHEMBL238	Electrochemical transporter	0.7023427491540327	2621 / 44
Cytochrome P450 2D6	CYP2D6	P10635	CHEMBL289	Cytochrome P450	0.6888521424110939	198 / 1
D(3) dopamine receptor	DRD3	P35462	CHEMBL234	Family A G protein-coupled receptor	0.6759873768378808	2528 / 5
D(2) dopamine receptor	DRD2	P14416	CHEMBL217	Family A G protein-coupled receptor	0.6759873768378808	4169 / 4
Tyrosine-protein kinase Fyn	FYN	P06241	CHEMBL1841	Kinase	0.6326159842890775	362 / 2
Epidermal growth factor receptor	EGFR	P00533	CHEMBL203	Kinase	0.6326159842890775	2726 / 2
Histamine H1 receptor	HRH1	P35367	CHEMBL231	Family A G protein-coupled receptor	0.6211298585241494	692 / 1
Kappa-type opioid receptor	OPRK1	P41145	CHEMBL237	Family A G protein-coupled receptor	0.6187130644418593	2262 / 8
Glutamate NMDA receptor; GRIN1/GRIN2B	N/A	Q05586&Q13224	CHEMBL1907603	Ligand-gated ion channel	0.6124593985938143	1003 / 4
Glutamate NMDA receptor; GRIN1/GRIN2A	N/A	Q05586&Q12879	CHEMBL1907604	Ligand-gated ion channel	0.6124593985938143	117 / 5
Histamine H2 receptor	HRH2	P25021	CHEMBL1941	Family A G protein-coupled receptor	0.5954749317107471	201 / 4
Alpha-1B adrenergic receptor	ADRA1B	P35368	CHEMBL232	Family A G protein-coupled receptor	0.5617267065096789	460 / 2
5-hydroxytryptamine receptor 5A	HTR5A	P47898	CHEMBL3426	Family A G protein-coupled receptor	0.5120367952992967	238 / 1
Alcohol dehydrogenase 1A	ADH1A	P07327	CHEMBL1970	Oxidoreductase	0.46649865335676827	16 / 16
Alcohol dehydrogenase 1C	ADH1C	P00326	CHEMBL3285	Oxidoreductase	0.46649865335676827	6 / 5
KiSS-1 receptor	KISS1R	Q969F8	CHEMBL5413	Family A G protein-coupled receptor	0.41859514856536817	12 / 3
Epoxide hydrolase 1	EPHX1	P07099	CHEMBL1968	Protease	0.35696142326031766	188 / 73
5-hydroxytryptamine receptor 1A	HTR1A	P08908	CHEMBL214	Family A G protein-coupled receptor	0.3550618065704798	2966 / 1
Lanosterol synthase	LSS	P48449	CHEMBL3593	Isomerase	0.34725393824110795	63 / 5
Mu-type opioid receptor	OPRM1	P35372	CHEMBL233	Family A G protein-coupled receptor	0.34456413512854955	2910 / 14
Nischarin	NISCH	Q9Y2I1	CHEMBL3923	Other cytosolic protein	0.29520699554733865	117 / 1
Multidrug and toxin extrusion protein 1	SLC47A1	Q96FL8	CHEMBL1743126	Electrochemical transporter	0.2856085586008504	13 / 1
Solute carrier family 22 member 2	SLC22A2	O15244	CHEMBL1743122	Electrochemical transporter	0.27834030425422956	8 / 1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	EBP	Q15125	CHEMBL4931	Isomerase	0.2556511672133145	46 / 4
Cyclin-dependent kinase 5/CDK5 activator 1	N/A	Q00535&Q15078	CHEMBL1907600	Kinase	0.22185755596129086	538 / 1
All-trans-retinol dehydrogenase [NAD(+)] ADH1B	ADH1B	P00325	CHEMBL3284	Oxidoreductase	0.21014577816354604	6 / 6
Phospholipase A2	PLA2G1B	P04054	CHEMBL4426	Hydrolase	0.2060111656153547	15 / 2
Phospholipase A2, membrane associated	PLA2G2A	P14555	CHEMBL3474	Hydrolase	0.19938093621764022	42 / 3
All-trans-retinol dehydrogenase [NAD(+)] ADH4	ADH4	P08319	CHEMBL2990	Oxidoreductase	0.19523251943930173	1 / 1
Vesicular acetylcholine transporter	SLC18A3	Q16572	CHEMBL4767	Electrochemical transporter	0.16485919508246136	175 / 4
Carbonic anhydrase 9	CA9	Q16790	CHEMBL3594	Lyase	0.16220898046638918	2288 / 11
Carbonic anhydrase 12	CA12	O43570	CHEMBL3242	Lyase	0.16220898046638918	1832 / 10
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1	INPP5D	Q92835	CHEMBL1781870	Phosphatase	0.15975726449673536	2 / 1
Carbonic anhydrase 4	CA4	P22748	CHEMBL3729	Lyase	0.1587542665335599	601 / 4
5-hydroxytryptamine receptor 6	HTR6	P50406	CHEMBL3371	Family A G protein-coupled receptor	0.15701747713477368	2850 / 1
3-oxo-5-alpha-steroid 4-dehydrogenase 2	SRD5A2	P31213	CHEMBL1856	Oxidoreductase	0.1553324132590326	262 / 28
Androgen receptor	AR	P10275	CHEMBL1871	Nuclear receptor	0.14795588352994213	1085 / 21
All-trans-retinol dehydrogenase [NAD(+)] ADH7	ADH7	P40394	CHEMBL3867	Oxidoreductase	0.14304813337036915	1 / 1
5-hydroxytryptamine receptor 2C	HTR2C	P28335	CHEMBL225	Family A G protein-coupled receptor	0.1422359614852744	2027 / 2
Fatty-acid amide hydrolase 1	FAAH	O00519	CHEMBL2243	Hydrolase	0.14053265565423254	654 / 7
Carbonic anhydrase 14	CA14	Q9ULX7	CHEMBL3510	Lyase	0.13926776967643198	312 / 4
Carbonic anhydrase 7	CA7	P43166	CHEMBL2326	Lyase	0.13926776967643198	672 / 4
Carbonic anhydrase 5A, mitochondrial	CA5A	P35218	CHEMBL4789	Lyase	0.13926776967643198	232 / 4
Carbonic anhydrase 6	CA6	P23280	CHEMBL3025	Lyase	0.13926776967643198	183 / 4
Carbonic anhydrase 3	CA3	P07451	CHEMBL2885	Lyase	0.13926776967643198	89 / 2
N-acylethanolamine-hydrolyzing acid amidase	NAAA	Q02083	CHEMBL4349	Hydrolase	0.13851804535526377	188 / 6
Carbonic anhydrase 5B, mitochondrial	CA5B	Q9Y2D0	CHEMBL3969	Lyase	0.13561987297666467	209 / 4
Amine oxidase [flavin-containing] A	MAOA	P21397	CHEMBL1951	Oxidoreductase	0.11998543945490493	701 / 1
11-beta-hydroxysteroid dehydrogenase 1	HSD11B1	P28845	CHEMBL4235	Oxidoreductase	0.10330648473618236	1828 / 47
Tyrosyl-DNA phosphodiesterase 1	TDP1	Q9NUW8	CHEMBL1075138	Phosphodiesterase	0.10197536166863226	48 / 1
Lysine-specific histone demethylase 1A	KDM1A	O60341	CHEMBL6136	Eraser	0.10137337371937112	1839 / 6
3-oxo-5-alpha-steroid 4-dehydrogenase 1	SRD5A1	P18405	CHEMBL1787	Oxidoreductase	0.0936794942839696	311 / 35
Bifunctional epoxide hydrolase 2	EPHX2	P34913	CHEMBL2409	Protease	0.0907414352755273	1061 / 139
Deoxyhypusine synthase	DHPS	P49366	CHEMBL4415	Transferase	0.08819164770795448	21 / 1
Nociceptin receptor	OPRL1	P41146	CHEMBL2014	Family A G protein-coupled receptor	0.08694093079088519	1618 / 12
11-beta-hydroxysteroid dehydrogenase type 2	HSD11B2	P80365	CHEMBL3746	Oxidoreductase	0.07661688985498134	48 / 4
Sodium-dependent serotonin transporter	SLC6A4	P31645	CHEMBL228	Electrochemical transporter	0.0749236079908074	3804 / 41
C-X-C chemokine receptor type 4	CXCR4	P61073	CHEMBL2107	Family A G protein-coupled receptor	0.0726647126475887	172 / 2
Metabotropic glutamate receptor 5	GRM5	P41594	CHEMBL3227	Family C G protein-coupled receptor	0.07033584246840893	737 / 2
Nitric oxide synthase, inducible	NOS2	P35228	CHEMBL4481	Enzyme	0.07030002791796275	410 / 38
Nitric oxide synthase 1	NOS1	P29475	CHEMBL3568	Oxidoreductase	0.07030002791796275	693 / 37
Lysine-specific demethylase 2B	KDM2B	Q8NHM5	CHEMBL3779760	Eraser	0.07012186975930654	308 / 1
Nitric oxide synthase 3	NOS3	P29474	CHEMBL4803	Enzyme	0.05773824883425278	228 / 19
Dipeptidyl peptidase 4	DPP4	P27487	CHEMBL284	Protease	0.05733265183388	2629 / 69
Transient receptor potential cation channel subfamily V member 1	TRPV1	Q8NER1	CHEMBL4794	Voltage-gated ion channel	0.052485852258033976	1085 / 1
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	PAOX	Q6QHF9	CHEMBL2105	Oxidoreductase	0.05202351023126	8 / 6
Carbonic anhydrase 1	CA1	P00915	CHEMBL261	Lyase	0.050482501038019004	2753 / 16
D(4) dopamine receptor	DRD4	P21917	CHEMBL219	Family A G protein-coupled receptor	0.05032097859318875	1614 / 1
G-protein coupled bile acid receptor 1	GPBAR1	Q8TDU6	CHEMBL5409	Family A G protein-coupled receptor	0.049902577344428975	181 / 1
Tyrosine-protein phosphatase non-receptor type 1	PTPN1	P18031	CHEMBL335	Phosphatase	0.049659978037645464	212 / 5
Glucocorticoid receptor	NR3C1	P04150	CHEMBL2034	Nuclear receptor	0.04570019775919117	1498 / 1
Aldehyde dehydrogenase 1A1	ALDH1A1	P00352	CHEMBL3577	Oxidoreductase	0.04472104512733136	176 / 1
Polyadenylate-binding protein 1	PABPC1	P11940	CHEMBL1293286	Unclassified protein	0.04460920402554704	35 / 1
5-hydroxytryptamine receptor 2B	HTR2B	P41595	CHEMBL1833	Family A G protein-coupled receptor	0.044132302418403206	882 / 2
5-hydroxytryptamine receptor 2A	HTR2A	P28223	CHEMBL224	Family A G protein-coupled receptor	0.044132302418403206	3076 / 2
Carbonic anhydrase 2	CA2	P00918	CHEMBL205	Lyase	0.04274979643578858	3318 / 16
Alpha-2A adrenergic receptor	ADRA2A	P08913	CHEMBL1867	Family A G protein-coupled receptor	0.042139630031690474	514 / 2
5-hydroxytryptamine receptor 7	HTR7	P34969	CHEMBL3155	Family A G protein-coupled receptor	0.0420186902308226	2009 / 1
Glucose-6-phosphate 1-dehydrogenase	G6PD	P11413	CHEMBL5347	Oxidoreductase	0.04166994198596542	22 / 4

*Probability for the query molecule - assumed as bioactive - to have this protein as target.