Target	Common name	Uniprot ID	ChEMBL ID	Target Class	Probability*	Known actives (3D/2D)
Glutamate NMDA receptor; GRIN1/GRIN2B	N/A	Q05586&Q13224	CHEMBL1907603	Ligand-gated ion channel	1.0	925 / 1
Glutamate NMDA receptor; GRIN1/GRIN2A	N/A	Q05586&Q12879	CHEMBL1907604	Ligand-gated ion channel	1.0	120 / 2
Acetylcholinesterase	ACHE	P22303	CHEMBL220	Hydrolase	1.0	1496 / 10
Multidrug and toxin extrusion protein 1	SLC47A1	Q96FL8	CHEMBL1743126	Electrochemical transporter	0.9667518274880263	10 / 1
Solute carrier family 22 member 2	SLC22A2	O15244	CHEMBL1743122	Electrochemical transporter	0.9667518274880263	7 / 1
Sigma non-opioid intracellular receptor 1	SIGMAR1	Q99720	CHEMBL287	Membrane receptor	0.9613772832700846	2263 / 23
Epoxide hydrolase 1	EPHX1	P07099	CHEMBL1968	Protease	0.9403807307717692	145 / 46
Nischarin	NISCH	Q9Y2I1	CHEMBL3923	Other cytosolic protein	0.8845479020080538	101 / 1
Cyclin-dependent kinase 5/CDK5 activator 1	N/A	Q00535&Q15078	CHEMBL1907600	Kinase	0.7989049424900448	411 / 1
Dynamin-1	DNM1	Q05193	CHEMBL4958	Hydrolase	0.7357297899536712	21 / 9
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1	INPP5D	Q92835	CHEMBL1781870	Phosphatase	0.6439061981414133	2 / 1
Carbonic anhydrase 9	CA9	Q16790	CHEMBL3594	Lyase	0.6394340483727878	2366 / 2
Carbonic anhydrase 12	CA12	O43570	CHEMBL3242	Lyase	0.6394340483727878	1869 / 3
Carbonic anhydrase 4	CA4	P22748	CHEMBL3729	Lyase	0.6277963081582943	602 / 5
Carbonic anhydrase 5B, mitochondrial	CA5B	Q9Y2D0	CHEMBL3969	Lyase	0.6124447156825816	192 / 2
Carbonic anhydrase 14	CA14	Q9ULX7	CHEMBL3510	Lyase	0.6124447156825816	289 / 3
Carbonic anhydrase 7	CA7	P43166	CHEMBL2326	Lyase	0.6124447156825816	640 / 3
Carbonic anhydrase 5A, mitochondrial	CA5A	P35218	CHEMBL4789	Lyase	0.6124447156825816	221 / 2
Carbonic anhydrase 6	CA6	P23280	CHEMBL3025	Lyase	0.6124447156825816	157 / 2
Carbonic anhydrase 3	CA3	P07451	CHEMBL2885	Lyase	0.6124447156825816	78 / 2
Neuronal acetylcholine receptor; alpha4/beta2	N/A	P17787&P43681	CHEMBL1907589	Ligand-gated ion channel	0.49089952503029943	578 / 14
Histamine H3 receptor	HRH3	Q9Y5N1	CHEMBL264	Family A G protein-coupled receptor	0.39151531985071536	1560 / 2
Neuronal acetylcholine receptor; alpha3/beta2	N/A	P17787&P32297	CHEMBL2109234	Ligand-gated ion channel	0.34796682390734174	41 / 1
Neuronal acetylcholine receptor subunit alpha-7	CHRNA7	P36544	CHEMBL2492	Ligand-gated ion channel	0.3468302205011669	751 / 4
Neuronal acetylcholine receptor; alpha2/beta4	N/A	P30926&Q15822	CHEMBL2109230	Ligand-gated ion channel	0.3468302205011669	9 / 1
Neuronal acetylcholine receptor; alpha3/beta4	N/A	P30926&P32297	CHEMBL1907594	Ligand-gated ion channel	0.3468302205011669	294 / 8
Acetylcholine receptor; alpha1/beta1/delta/gamma	N/A	P02708&P07510&P11230&Q07001	CHEMBL1907588	Ligand-gated ion channel	0.34569536135403645	16 / 2
Sodium-dependent noradrenaline transporter	SLC6A2	P23975	CHEMBL222	Electrochemical transporter	0.3050687232877209	2752 / 2
Cholinesterase	BCHE	P06276	CHEMBL1914	Hydrolase	0.2955390374914337	988 / 7
Sodium-dependent dopamine transporter	SLC6A3	Q01959	CHEMBL238	Electrochemical transporter	0.24369868312355614	2547 / 2
Bifunctional epoxide hydrolase 2	EPHX2	P34913	CHEMBL2409	Protease	0.23532961055285595	994 / 61
UDP-glucuronosyltransferase 2B7	UGT2B7	P16662	CHEMBL4370	Transferase	0.22034006888674276	8 / 1
Voltage-gated inwardly rectifying potassium channel KCNH2	KCNH2	Q12809	CHEMBL240	Voltage-gated ion channel	0.22020777621767348	3229 / 1
Alpha-2C adrenergic receptor	ADRA2C	P18825	CHEMBL1916	Family A G protein-coupled receptor	0.21678356659943887	366 / 5
Muscarinic acetylcholine receptor M1	CHRM1	P11229	CHEMBL216	Family A G protein-coupled receptor	0.21678356659943887	891 / 5
Muscarinic acetylcholine receptor M5	CHRM5	P08912	CHEMBL2035	Family A G protein-coupled receptor	0.21678356659943887	319 / 7
Muscarinic acetylcholine receptor M4	CHRM4	P08173	CHEMBL1821	Family A G protein-coupled receptor	0.21678356659943887	512 / 6
Muscarinic acetylcholine receptor M2	CHRM2	P08172	CHEMBL211	Family A G protein-coupled receptor	0.21678356659943887	839 / 5
Histamine H1 receptor	HRH1	P35367	CHEMBL231	Family A G protein-coupled receptor	0.19889664900669826	678 / 1
D(2) dopamine receptor	DRD2	P14416	CHEMBL217	Family A G protein-coupled receptor	0.19493267291527647	3889 / 1
Muscarinic acetylcholine receptor M3	CHRM3	P20309	CHEMBL245	Family A G protein-coupled receptor	0.19078172321862671	848 / 4
Cytochrome P450 2D6	CYP2D6	P10635	CHEMBL289	Cytochrome P450	0.19078172321862671	198 / 1
Alpha-2B adrenergic receptor	ADRA2B	P18089	CHEMBL1942	Family A G protein-coupled receptor	0.1842583090256458	314 / 4
Carbonic anhydrase 2	CA2	P00918	CHEMBL205	Lyase	0.17565811445767215	3303 / 7
Bile acid receptor	NR1H4	Q96RI1	CHEMBL2047	Nuclear receptor	0.16120647995409976	627 / 5
Carbonic anhydrase 1	CA1	P00915	CHEMBL261	Lyase	0.16025381282906576	2772 / 8
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	PAOX	Q6QHF9	CHEMBL2105	Oxidoreductase	0.14474359069621326	9 / 5
D(3) dopamine receptor	DRD3	P35462	CHEMBL234	Family A G protein-coupled receptor	0.135352625581924	2388 / 1
Histamine H2 receptor	HRH2	P25021	CHEMBL1941	Family A G protein-coupled receptor	0.135352625581924	192 / 1
G-protein coupled bile acid receptor 1	GPBAR1	Q8TDU6	CHEMBL5409	Family A G protein-coupled receptor	0.1261934553095946	220 / 1
Epidermal growth factor receptor	EGFR	P00533	CHEMBL203	Kinase	0.12386731987812329	2462 / 2
Nitric oxide synthase, inducible	NOS2	P35228	CHEMBL4481	Enzyme	0.12289216706472372	374 / 18
Sphingosine kinase 1	SPHK1	Q9NYA1	CHEMBL4394	Enzyme	0.12269294263450235	158 / 2
Tyrosine-protein kinase Fyn	FYN	P06241	CHEMBL1841	Kinase	0.11542144954477165	307 / 2
KiSS-1 receptor	KISS1R	Q969F8	CHEMBL5413	Family A G protein-coupled receptor	0.1134859040245735	13 / 3
Sodium-dependent serotonin transporter	SLC6A4	P31645	CHEMBL228	Electrochemical transporter	0.10964700099219392	3599 / 1
Transient receptor potential cation channel subfamily V member 1	TRPV1	Q8NER1	CHEMBL4794	Voltage-gated ion channel	0.10085483754184778	1273 / 1
Alcohol dehydrogenase 1A	ADH1A	P07327	CHEMBL1970	Oxidoreductase	0.10023195649169318	12 / 9
Alcohol dehydrogenase 1C	ADH1C	P00326	CHEMBL3285	Oxidoreductase	0.10023195649169318	4 / 4
5-hydroxytryptamine receptor 5A	HTR5A	P47898	CHEMBL3426	Family A G protein-coupled receptor	0.09748993582249386	248 / 1
Toll-like receptor 4	TLR4	O00206	CHEMBL5255	Toll-like and Il-1 receptors	0.09069427473373422	30 / 2
Plasminogen	PLG	P00747	CHEMBL1801	Protease	0.08978068511440465	164 / 2
5-hydroxytryptamine receptor 2A	HTR2A	P28223	CHEMBL224	Family A G protein-coupled receptor	0.08666527029005441	2822 / 1
5-hydroxytryptamine receptor 2C	HTR2C	P28335	CHEMBL225	Family A G protein-coupled receptor	0.08470155202160201	1839 / 2
Aminopeptidase N	ANPEP	P15144	CHEMBL1907	Protease	0.08229052802892318	60 / 5
Lysine-specific histone demethylase 1A	KDM1A	O60341	CHEMBL6136	Eraser	0.08155927000060549	1989 / 2
Alpha-1B adrenergic receptor	ADRA1B	P35368	CHEMBL232	Family A G protein-coupled receptor	0.07973003277265774	367 / 1
Kappa-type opioid receptor	OPRK1	P41145	CHEMBL237	Family A G protein-coupled receptor	0.07936295725573543	1985 / 3
5-hydroxytryptamine receptor 1A	HTR1A	P08908	CHEMBL214	Family A G protein-coupled receptor	0.07215189649731853	2667 / 1
Alpha-2A adrenergic receptor	ADRA2A	P08913	CHEMBL1867	Family A G protein-coupled receptor	0.06624667697428026	464 / 1
Tyrosine-protein phosphatase non-receptor type 1	PTPN1	P18031	CHEMBL335	Phosphatase	0.06585267060763898	168 / 2
5-hydroxytryptamine receptor 2B	HTR2B	P41595	CHEMBL1833	Family A G protein-coupled receptor	0.06562912838678185	858 / 1
Melanocortin receptor 5	MC5R	P33032	CHEMBL4608	Family A G protein-coupled receptor	0.06562912838678185	180 / 1
Mu-type opioid receptor	OPRM1	P35372	CHEMBL233	Family A G protein-coupled receptor	0.06330046148408736	3059 / 3
Androgen receptor	AR	P10275	CHEMBL1871	Nuclear receptor	0.05733095626022466	1117 / 11
N-acylethanolamine-hydrolyzing acid amidase	NAAA	Q02083	CHEMBL4349	Hydrolase	0.057324069825407664	195 / 2
Lanosterol synthase	LSS	P48449	CHEMBL3593	Isomerase	0.055582656869823145	83 / 1
Sex hormone-binding globulin	SHBG	P04278	CHEMBL3305	Secreted protein	0.054663140560581094	27 / 2
Phospholipase A2, membrane associated	PLA2G2A	P14555	CHEMBL3474	Hydrolase	0.05078897993098969	36 / 2
Phospholipase A2	PLA2G1B	P04054	CHEMBL4426	Hydrolase	0.05078897993098969	18 / 2
Amine oxidase [flavin-containing] B	MAOB	P27338	CHEMBL2039	Oxidoreductase	0.05055676245367461	950 / 0
Amine oxidase [flavin-containing] A	MAOA	P21397	CHEMBL1951	Oxidoreductase	0.05055676245367461	558 / 0
Sodium channel protein type 4 subunit alpha	SCN4A	P35499	CHEMBL2072	Voltage-gated ion channel	0.04843433547091889	28 / 0
Voltage-dependent calcium channel subunit alpha-2/delta-1	CACNA2D1	P54289	CHEMBL1919	Calcium channel auxiliary subunit alpha2delta family	0.04671899590027758	323 / 2
LSD1/CoREST complex	N/A	O60341&Q9UKL0	CHEMBL3137262	Eraser	0.0463966560883406	69 / 0
All-trans-retinol dehydrogenase [NAD(+)] ADH1B	ADH1B	P00325	CHEMBL3284	Oxidoreductase	0.04556775881197946	3 / 5
Proto-oncogene tyrosine-protein kinase receptor Ret	RET	P07949	CHEMBL2041	Kinase	0.04444070015966683	889 / 0
5-hydroxytryptamine receptor 6	HTR6	P50406	CHEMBL3371	Family A G protein-coupled receptor	0.04255252024536413	2626 / 1
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-3/calcium channel subunit alpha-2/delta-1	N/A	P54289&Q13936&P54284	CHEMBL6066567	Voltage-gated ion channel	0.04015951347293729	4 / 1
Metabotropic glutamate receptor 5	GRM5	P41594	CHEMBL3227	Family C G protein-coupled receptor	0.03913345351060764	565 / 2
Tissue alpha-L-fucosidase	FUCA1	P04066	CHEMBL4176	Hydrolase	0.039027124278050045	25 / 4
Cytochrome P450 2C19	CYP2C19	P33261	CHEMBL3622	Cytochrome P450	0.03792128768357947	71 / 0
Cytochrome P450 11B2, mitochondrial	CYP11B2	P19099	CHEMBL2722	Cytochrome P450	0.03708386219480876	879 / 1
Cytochrome P450 11B1, mitochondrial	CYP11B1	P15538	CHEMBL1908	Cytochrome P450	0.03708386219480876	520 / 1
Endoplasmic reticulum aminopeptidase 1	ERAP1	Q9NZ08	CHEMBL5939	Protease	0.03707468064750478	29 / 1
Endoplasmic reticulum aminopeptidase 2	ERAP2	Q6P179	CHEMBL5043	Protease	0.03707468064750478	26 / 1
Kinesin-like protein KIF11	KIF11	P52732	CHEMBL4581	Other cytosolic protein	0.03701727831841647	479 / 0
11-beta-hydroxysteroid dehydrogenase 1	HSD11B1	P28845	CHEMBL4235	Oxidoreductase	0.036727475177442535	2022 / 17
Leukotriene A-4 hydrolase	LTA4H	P09960	CHEMBL4618	Protease	0.03589129835708042	161 / 1
Tyrosyl-DNA phosphodiesterase 1	TDP1	Q9NUW8	CHEMBL1075138	Phosphodiesterase	0.035546916076070904	39 / 1

*Probability for the query molecule - assumed as bioactive - to have this protein as target.