Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.522433360495
 10 / 27     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.330471165208
 80 / 35     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.156518424737
 103 / 1     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.156518424737
 175 / 3     
Tyrosine-protein kinase FYN FYN P06241 CHEMBL1841 Kinase 0.146856850103
 0 / 1     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.146856850103
 0 / 1     
Dynamin-1 DNM1 Q05193 CHEMBL4958 Enzyme 0.146856850103
 0 / 13     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.146856850103
 13 / 4     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.135105167765
 8 / 6     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.125817530785
 6 / 7     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.0952559184207
 12 / 3     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.0849737018175
 5 / 6     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0849737018175
 33 / 2     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0849737018175
 4 / 5     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0849737018175
 3 / 3     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.0743164735672
 7 / 16     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0743164735672
 4 / 5     
3-phosphoinositide dependent protein kinase-1 PDPK1 O15530 CHEMBL2534 Kinase 0.0649510872641
 1 / 0     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0649510872641
 4 / 3     
Trace amine-associated receptor 1 (by homology) TAAR1 Q96RJ0 CHEMBL5857 Family A G protein-coupled receptor 0.0649510872641
 5 / 0     
High-affinity choline transporter (by homology) SLC5A7 Q9GZV3 CHEMBL4507 Electrochemical transporter 0.0544879468076
 0 / 3     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.0544879468076
 0 / 1     
Phospholipase A2 group IIA PLA2G2A P14555 CHEMBL3474 Enzyme 0.0544879468076
 0 / 2     
Phospholipase A2 group 1B PLA2G1B P04054 CHEMBL4426 Enzyme 0.0544879468076
 0 / 2     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0443083186041
 5 / 6     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.0443083186041
 12 / 1     
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 0.0443083186041
 22 / 0     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.0443083186041
 1 / 1     
Neuronal acetylcholine receptor protein alpha-7 subunit CHRNA7 P36544 CHEMBL2492 Ligand-gated ion channel 0.033970689612
 5 / 13     
Neuronal acetylcholine receptor; alpha2/beta4 CHRNB4 CHRNA2 P30926 Q15822 CHEMBL2109230 Ligand-gated ion channel 0.033970689612
 1 / 1     
Neuronal acetylcholine receptor; alpha3/beta2 CHRNA3 CHRNB2 P32297 P17787 CHEMBL2109234 Ligand-gated ion channel 0.033970689612
 1 / 1     
Anti-estrogen binding site (AEBS) EBP Q15125 CHEMBL4931 Enzyme 0.033970689612
 0 / 3     
Alcohol dehydrogenase alpha chain ADH1A P07327 CHEMBL1970 Oxidoreductase 0.033970689612
 0 / 13     
Alcohol dehydrogenase gamma chain ADH1C P00326 CHEMBL3285 Oxidoreductase 0.033970689612
 0 / 5     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0238327432783
 19 / 1     
Phenylethanolamine N-methyltransferase PNMT P11086 CHEMBL4617 Enzyme 0.0238327432783
 6 / 0     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.0238327432783
 14 / 0     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0238327432783
 1 / 0     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0238327432783
 3 / 1     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.0238327432783
 1 / 1     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.0238327432783
 3 / 1     
Polyadenylate-binding protein 1 PABPC1 P11940 CHEMBL1293286 Unclassified protein 0.0238327432783
 0 / 1     
Polyamine oxidase PAOX Q6QHF9 CHEMBL2105 Enzyme 0.0
 0 / 5     
UDP-glucuronosyltransferase 2B7 UGT2B7 P16662 CHEMBL4370 Enzyme 0.0
 0 / 1     
Vesicular acetylcholine transporter SLC18A3 Q16572 CHEMBL4767 Electrochemical transporter 0.0
 0 / 4     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.0
 52 / 0     
Monoamine oxidase A MAOA P21397 CHEMBL1951 Oxidoreductase 0.0
 24 / 1     
Steroid 5-alpha-reductase 2 SRD5A2 P31213 CHEMBL1856 Oxidoreductase 0.0
 0 / 25     
Metabotropic glutamate receptor 5 GRM5 P41594 CHEMBL3227 Family C G protein-coupled receptor 0.0
 0 / 1     
Lanosterol synthase LSS P48449 CHEMBL3593 Enzyme 0.0
 0 / 3     
11-beta-hydroxysteroid dehydrogenase 1 HSD11B1 P28845 CHEMBL4235 Enzyme 0.0
 0 / 20     
Anandamide amidohydrolase FAAH O00519 CHEMBL2243 Enzyme 0.0
 0 / 7     
Nischarin NISCH Q9Y2I1 CHEMBL3923 Other cytosolic protein 0.0
 1 / 1     
Synaptic vesicular amine transporter (by homology) SLC18A2 Q05940 CHEMBL1893 Electrochemical transporter 0.0
 3 / 11     
Protein arginine N-methyltransferase 6 PRMT6 Q96LA8 CHEMBL1275221 Writer 0.0
 0 / 1     
Histone-arginine methyltransferase CARM1 CARM1 Q86X55 CHEMBL5406 Writer 0.0
 0 / 1     
Lysine-specific histone demethylase 1 KDM1A O60341 CHEMBL6136 Eraser 0.0
 6 / 1     
Cytochrome P450 2A6 CYP2A6 P11509 CHEMBL5282 Cytochrome P450 0.0
 1 / 0     
Epoxide hydrolase 1 EPHX1 P07099 CHEMBL1968 Protease 0.0
 0 / 19     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.0
 9 / 0     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0
 33 / 1     
Epoxide hydratase EPHX2 P34913 CHEMBL2409 Protease 0.0
 0 / 16     
N-acylsphingosine-amidohydrolase NAAA Q02083 CHEMBL4349 Enzyme 0.0
 0 / 2     
Steroid 5-alpha-reductase 1 SRD5A1 P18405 CHEMBL1787 Oxidoreductase 0.0
 0 / 33     
3-keto-steroid reductase HSD17B7 P56937 CHEMBL5999 Enzyme 0.0
 0 / 2     
Carbonic anhydrase II CA2 P00918 CHEMBL205 Lyase 0.0
 0 / 5     
Carbonic anhydrase VII CA7 P43166 CHEMBL2326 Lyase 0.0
 0 / 3     
Carbonic anhydrase I CA1 P00915 CHEMBL261 Lyase 0.0
 0 / 5     
Carbonic anhydrase VI CA6 P23280 CHEMBL3025 Lyase 0.0
 0 / 3     
Carbonic anhydrase XIV CA14 Q9ULX7 CHEMBL3510 Lyase 0.0
 0 / 3     
Carbonic anhydrase IX CA9 Q16790 CHEMBL3594 Lyase 0.0
 0 / 5     
Carbonic anhydrase IV CA4 P22748 CHEMBL3729 Lyase 0.0
 0 / 3     
Carbonic anhydrase VB CA5B Q9Y2D0 CHEMBL3969 Lyase 0.0
 0 / 3     
Carbonic anhydrase VA CA5A P35218 CHEMBL4789 Lyase 0.0
 0 / 3     
Caspase-2 CASP2 P42575 CHEMBL4884 Protease 0.0
 0 / 1     
Carboxylesterase 2 CES2 O00748 CHEMBL3180 Enzyme 0.0
 0 / 1     
Alcohol dehydrogenase beta chain ADH1B P00325 CHEMBL3284 Oxidoreductase 0.0
 0 / 4     
Alcohol dehydrogenase class IV ADH7 P40394 CHEMBL3867 Enzyme 0.0
 0 / 1     
Metastin receptor KISS1R Q969F8 CHEMBL5413 Family A G protein-coupled receptor 0.0
 0 / 1     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.0
 3 / 8     
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET RET P07949 CHEMBL2041 Kinase 0.0
 2 / 0     
Carbonic anhydrase XII CA12 O43570 CHEMBL3242 Lyase 0.0
 0 / 4     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0
 13 / 1     
Serotonin transporter (by homology) SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0
 156 / 1     
Methionine aminopeptidase 1 METAP1 P53582 CHEMBL2474 Protease 0.0
 0 / 1     
Alcohol dehydrogenase class II ADH4 P08319 CHEMBL2990 Enzyme 0.0
 0 / 1     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.0
 8 / 0     
Solute carrier family 22 member 2 SLC22A2 O15244 CHEMBL1743122 Electrochemical transporter 0.0
 1 / 1     
Multidrug and toxin extrusion protein 1 SLC47A1 Q96FL8 CHEMBL1743126 Electrochemical transporter 0.0
 1 / 1     
Beta-glucocerebrosidase GBA P04062 CHEMBL2179 Enzyme 0.0
 0 / 24     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.0
 0 / 15     
Dipeptidyl peptidase VIII DPP8 Q6V1X1 CHEMBL4657 Protease 0.0
 0 / 4     
Glutamate NMDA receptor; GRIN1/GRIN2B GRIN1 GRIN2B Q05586 Q13224 CHEMBL1907603 Ligand-gated ion channel 0.0
 2 / 1     
Glutamate NMDA receptor; GRIN1/GRIN2A GRIN2A GRIN1 Q12879 Q05586 CHEMBL1907604 Ligand-gated ion channel 0.0
 2 / 1     
Glutamate [NMDA] receptor PROTEIN GRIN1 Q05586 CHEMBL2015 Ligand-gated ion channel 0.0
 1 / 1     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.0
 6 / 8     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.0
 9 / 0     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.0
 9 / 0     
Estrogen receptor beta ESR2 Q92731 CHEMBL242 Nuclear receptor 0.0
 1 / 0     
Protein tyrosine kinase 2 beta PTK2B Q14289 CHEMBL5469 Kinase 0.0
 1 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.