In order to avoid security-related warning messages when switching to secured connection, you may want either to:

Click here to proceed.




Target prediction has been submitted.

Calculations can take up to one minute.
Please be patient.

Loading...

This website allows you to estimate the most probable macromolecular targets of a small molecule, assumed as bioactive. The prediction is founded on a combination of 2D and 3D similarity with a library of 370'000 known actives on more than 3000 proteins from three different species.

The webtool is described in detail here: SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules, Nucl. Acids Res. (2019). For technical information about the prediction algorithm, you can refer to: Shaping the interaction landscape of bioactive molecules, Bioinformatics (2013) 29:3073-3079.
Please, take our survey to find out how you use our tools and how we could improve them. It only takes 8 min.
Select a species
Homo sapiens
Mus musculus
Rattus norvegicus
Paste a SMILES in this box, or draw a molecule

(Provide a SMILES before submitting)