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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.697501031388
 1062 / 298     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.670876754555
 821 / 77     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.661620920662
 85 / 51     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.661620920662
 161 / 195     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.661620920662
 419 / 215     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.661620920662
 241 / 131     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.462007056192
 362 / 215     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.316824689204
 100 / 312     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.316824689204
 107 / 288     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.171518552462
 646 / 73     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.162404208274
 36 / 11     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.162404208274
 32 / 9     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.162404208274
 29 / 10     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.162404208274
 7 / 12     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.162404208274
 55 / 39     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.162404208274
 100 / 8     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.162404208274
 8 / 9     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.162404208274
 189 / 88     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.162404208274
 32 / 45     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.162404208274
 358 / 48     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.126154249845
 21 / 49     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.117056357516
 92 / 57     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0807923867549
 436 / 252     
Beta-1 adrenergic receptor ADRB1 P08588 CHEMBL213 Family A G protein-coupled receptor 0.0807923867549
 6 / 13     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.071715932485
 36 / 25     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.071715932485
 20 / 33     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.0626219668353
 62 / 119     
Transient receptor potential cation channel subfamily M member 8 (by homology) TRPM8 Q7Z2W7 CHEMBL1075319 Voltage-gated ion channel 0.0626219668353
 1 / 1     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.0626219668353
 142 / 25     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0626219668353
 3 / 1     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.0626219668353
 20 / 10     
Melatonin receptor 1A MTNR1A P48039 CHEMBL1945 Family A G protein-coupled receptor 0.0626219668353
 0 / 120     
Melatonin receptor 1B MTNR1B P49286 CHEMBL1946 Family A G protein-coupled receptor 0.0626219668353
 0 / 110     
Serotonin 3a (5-HT3a) receptor HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0535560755162
 59 / 11     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0535560755162
 25 / 1     
Dopamine D5 receptor DRD5 P21918 CHEMBL1850 Family A G protein-coupled receptor 0.0535560755162
 21 / 20     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.0535560755162
 107 / 26     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.0535560755162
 20 / 51     
DNA (cytosine-5)-methyltransferase 1 (by homology) DNMT1 P26358 CHEMBL1993 Writer 0.0535560755162
 0 / 3     
Melanocortin receptor 5 MC5R P33032 CHEMBL4608 Family A G protein-coupled receptor 0.0535560755162
 2 / 48     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.0535560755162
 186 / 45     
Interferon-alpha/beta receptor alpha chain IFNAR1 P17181 CHEMBL1887 Membrane receptor 0.0535560755162
 1 / 0     
Squalene synthetase (by homology) FDFT1 P37268 CHEMBL3338 Enzyme 0.0535560755162
 10 / 0     
Vanilloid receptor TRPV1 Q8NER1 CHEMBL4794 Voltage-gated ion channel 0.0535560755162
 1 / 12     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.0535560755162
 1 / 11     
Nociceptin receptor OPRL1 P41146 CHEMBL2014 Family A G protein-coupled receptor 0.0535560755162
 41 / 25     
Tyrosine-protein kinase FYN FYN P06241 CHEMBL1841 Kinase 0.0535560755162
 3 / 0     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.0535560755162
 46 / 0     
Potassium channel subfamily K member 2 KCNK2 O95069 CHEMBL2321615 Voltage-gated ion channel 0.0535560755162
 1 / 0     
Prion protein PRNP P04156 CHEMBL4869 Surface antigen 0.0535560755162
 4 / 0     
Calmodulin CALM1 P62158 CHEMBL6093 Unclassified protein 0.0535560755162
 1 / 0     
Cyclooxygenase-1 (by homology) PTGS1 P23219 CHEMBL221 Oxidoreductase 0.0535560755162
 1 / 0     
Melanocortin receptor 4 MC4R P32245 CHEMBL259 Family A G protein-coupled receptor 0.0535560755162
 0 / 88     
Matrix metalloproteinase 9 MMP9 P14780 CHEMBL321 Protease 0.0535560755162
 0 / 23     
Melanocortin receptor 1 (by homology) MC1R Q01726 CHEMBL3795 Family A G protein-coupled receptor 0.0535560755162
 0 / 71     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.0535560755162
 41 / 6     
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET RET P07949 CHEMBL2041 Kinase 0.0535560755162
 4 / 0     
Neuronal acetylcholine receptor protein alpha-7 subunit CHRNA7 P36544 CHEMBL2492 Ligand-gated ion channel 0.0535560755162
 21 / 9     
Cyclin-dependent kinase 4/cyclin D1 CCND1 CDK4 P24385 P11802 CHEMBL1907601 Kinase 0.0535560755162
 0 / 23     
Cyclin-dependent kinase 4 CDK4 P11802 CHEMBL331 Kinase 0.0535560755162
 0 / 3     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.0535560755162
 10 / 43     
Anandamide amidohydrolase FAAH O00519 CHEMBL2243 Enzyme 0.0535560755162
 0 / 1     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0535560755162
 137 / 2     
LSD1/CoREST complex RCOR1 KDM1A Q9UKL0 O60341 CHEMBL3137262 Eraser 0.0535560755162
 13 / 0     
Kinesin-like protein 1 KIF11 P52732 CHEMBL4581 Other cytosolic protein 0.0535560755162
 48 / 23     
Neurokinin 1 receptor TACR1 P25103 CHEMBL249 Family A G protein-coupled receptor 0.0535560755162
 7 / 83     
Melanocortin receptor 3 MC3R P41968 CHEMBL4644 Family A G protein-coupled receptor 0.0535560755162
 0 / 47     
Quinone reductase 2 NQO2 P16083 CHEMBL3959 Enzyme 0.0535560755162
 1 / 14     
Sodium channel protein type IX alpha subunit SCN9A Q15858 CHEMBL4296 Voltage-gated ion channel 0.0
 1 / 0     
Glutamate [NMDA] receptor subunit epsilon 2 GRIN2B Q13224 CHEMBL1904 Ligand-gated ion channel 0.0
 14 / 1     
Cytochrome P450 2C19 CYP2C19 P33261 CHEMBL3622 Cytochrome P450 0.0
 3 / 0     
Beta-3 adrenergic receptor ADRB3 P13945 CHEMBL246 Family A G protein-coupled receptor 0.0
 0 / 6     
Nischarin NISCH Q9Y2I1 CHEMBL3923 Other cytosolic protein 0.0
 0 / 4     
GABA receptor alpha-5 subunit (by homology) GABRA5 P31644 CHEMBL5112 Ligand-gated ion channel 0.0
 0 / 9     
GABA receptor alpha-1 subunit (by homology) GABRA1 P14867 CHEMBL1962 Ligand-gated ion channel 0.0
 0 / 11     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.0
 13 / 0     
Histone-lysine N-methyltransferase SETD7 SETD7 Q8WTS6 CHEMBL5523 Writer 0.0
 2 / 0     
S-100 protein beta chain S100B P04271 CHEMBL4300 Other cytosolic protein 0.0
 1 / 0     
Monoamine oxidase A MAOA P21397 CHEMBL1951 Oxidoreductase 0.0
 45 / 4     
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 0.0
 39 / 4     
Cytochrome P450 51 CYP51A1 Q16850 CHEMBL3849 Cytochrome P450 0.0
 0 / 3     
Phenylethanolamine N-methyltransferase PNMT P11086 CHEMBL4617 Enzyme 0.0
 8 / 0     
Multidrug and toxin extrusion protein 1 SLC47A1 Q96FL8 CHEMBL1743126 Electrochemical transporter 0.0
 0 / 1     
Myosin light chain kinase, smooth muscle MYLK Q15746 CHEMBL2428 Kinase 0.0
 3 / 0     
C-X-C chemokine receptor type 3 CXCR3 P49682 CHEMBL4441 Family A G protein-coupled receptor 0.0
 16 / 0     
Adenosine A2a receptor ADORA2A P29274 CHEMBL251 Family A G protein-coupled receptor 0.0
 0 / 4     
Neurokinin 3 receptor TACR3 P29371 CHEMBL4429 Family A G protein-coupled receptor 0.0
 0 / 6     
Endothelin-converting enzyme 1 ECE1 P42892 CHEMBL4791 Protease 0.0
 0 / 28     
Nuclear receptor subfamily 1 group D member 2 NR1D2 Q14995 CHEMBL1961784 Nuclear receptor 0.0
 1 / 0     
Vesicular acetylcholine transporter SLC18A3 Q16572 CHEMBL4767 Electrochemical transporter 0.0
 2 / 0     
Tyrosinase TYR P14679 CHEMBL1973 Oxidoreductase 0.0
 0 / 1     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0
 0 / 49     
Cytochrome P450 1A2 CYP1A2 P05177 CHEMBL3356 Cytochrome P450 0.0
 1 / 0     
Glutamate NMDA receptor; GRIN1/GRIN2B GRIN1 GRIN2B Q05586 Q13224 CHEMBL1907603 Ligand-gated ion channel 0.0
 1 / 0     
Calcium sensing receptor CASR P41180 CHEMBL1878 Family C G protein-coupled receptor 0.0
 2 / 0     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.0
 81 / 0     
Anti-estrogen binding site (AEBS) EBP Q15125 CHEMBL4931 Enzyme 0.0
 4 / 0     
Voltage-gated potassium channel subunit Kv1.3 KCNA3 P22001 CHEMBL4633 Voltage-gated ion channel 0.0
 3 / 0     
Vascular endothelial growth factor receptor 3 FLT4 P35916 CHEMBL1955 Kinase 0.0
 0 / 7     
Insulin-like growth factor I receptor IGF1R P08069 CHEMBL1957 Kinase 0.0
 0 / 9     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.