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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
GABA transporter 1 (by homology) SLC6A1 P30531 CHEMBL1903 Electrochemical transporter 0.113285953487
211 / 0     
C-C chemokine receptor type 5 CCR5 P51681 CHEMBL274 Family A G protein-coupled receptor 0.113285953487
6 / 0     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.113285953487
6 / 0     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.113285953487
8 / 0     
Delta opioid receptor OPRD1 P41143 CHEMBL236 Family A G protein-coupled receptor 0.113285953487
102 / 0     
Peroxisome proliferator-activated receptor delta PPARD Q03181 CHEMBL3979 Nuclear receptor 0.113285953487
24 / 0     
Sphingosine 1-phosphate receptor Edg-8 S1PR5 Q9H228 CHEMBL2274 Family A G protein-coupled receptor 0.113285953487
41 / 0     
Sphingosine 1-phosphate receptor Edg-1 S1PR1 P21453 CHEMBL4333 Family A G protein-coupled receptor 0.113285953487
83 / 0     
Estrogen receptor alpha ESR1 P03372 CHEMBL206 Nuclear receptor 0.113285953487
59 / 0     
Integrin alpha-V/beta-3 ITGAV ITGB3 P06756 P05106 CHEMBL1907598 Membrane receptor 0.113285953487
187 / 0     
Integrin alpha-5/beta-1 ITGB1 ITGA5 P05556 P08648 CHEMBL2095226 Membrane receptor 0.113285953487
9 / 0     
Phosphodiesterase 7A PDE7A Q13946 CHEMBL3012 Phosphodiesterase 0.113285953487
5 / 0     
Endothelin receptor ET-A (by homology) EDNRA P25101 CHEMBL252 Family A G protein-coupled receptor 0.113285953487
212 / 0     
Carboxypeptidase B2 isoform A CPB2 Q96IY4 CHEMBL3419 Protease 0.113285953487
37 / 0     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.113285953487
101 / 0     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.113285953487
135 / 0     
Prolyl endopeptidase PREP P48147 CHEMBL3202 Protease 0.113285953487
5 / 0     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.113285953487
10 / 0     
Dipeptidyl peptidase VIII DPP8 Q6V1X1 CHEMBL4657 Protease 0.113285953487
12 / 0     
Fibroblast activation protein alpha FAP Q12884 CHEMBL4683 Protease 0.113285953487
5 / 0     
Dipeptidyl peptidase IX DPP9 Q86TI2 CHEMBL4793 Protease 0.113285953487
11 / 0     
Progesterone receptor PGR P06401 CHEMBL208 Nuclear receptor 0.113285953487
12 / 0     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.113285953487
63 / 0     
Casein kinase II alpha CSNK2A1 P68400 CHEMBL3629 Kinase 0.113285953487
75 / 0     
Lethal(3)malignant brain tumor-like protein 3 L3MBTL3 Q96JM7 CHEMBL1287623 Reader 0.113285953487
1 / 0     
11-beta-hydroxysteroid dehydrogenase 2 HSD11B2 P80365 CHEMBL3746 Enzyme 0.113285953487
3 / 0     
Leukotriene A4 hydrolase LTA4H P09960 CHEMBL4618 Protease 0.113285953487
74 / 0     
Mineralocorticoid receptor NR3C2 P08235 CHEMBL1994 Nuclear receptor 0.113285953487
3 / 0     
Prostanoid IP receptor PTGIR P43119 CHEMBL1995 Family A G protein-coupled receptor 0.113285953487
26 / 0     
Glycine transporter 1 SLC6A9 P48067 CHEMBL2337 Electrochemical transporter 0.113285953487
85 / 0     
Lysine-specific demethylase 5A KDM5A P29375 CHEMBL2424504 Eraser 0.113285953487
8 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.113285953487
23 / 0     
Cytochrome P450 26A1 CYP26A1 O43174 CHEMBL5141 Cytochrome P450 0.113285953487
11 / 0     
Serine/threonine-protein kinase PLK1 PLK1 P53350 CHEMBL3024 Kinase 0.113285953487
14 / 0     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.113285953487
2 / 0     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.113285953487
4 / 0     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.113285953487
4 / 0     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.113285953487
9 / 0     
Leucine aminopeptidase LAP3 P28838 CHEMBL3965 Protease 0.113285953487
6 / 0     
Lysine-specific demethylase 4C KDM4C Q9H3R0 CHEMBL6175 Eraser 0.113285953487
15 / 0     
Prostanoid EP2 receptor PTGER2 P43116 CHEMBL1881 Family A G protein-coupled receptor 0.113285953487
129 / 0     
Integrin alpha-4/beta-7 ITGB7 ITGA4 P26010 P13612 CHEMBL2095184 Membrane receptor 0.113285953487
34 / 0     
Integrin alpha-2/beta-3 ITGA2 ITGB3 P17301 P05106 CHEMBL2111461 Membrane receptor 0.113285953487
12 / 0     
Calcium sensing receptor CASR P41180 CHEMBL1878 Family C G protein-coupled receptor 0.113285953487
29 / 0     
Aminopeptidase B RNPEP Q9H4A4 CHEMBL2432 Protease 0.113285953487
3 / 0     
Nociceptin receptor OPRL1 P41146 CHEMBL2014 Family A G protein-coupled receptor 0.113285953487
8 / 0     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.113285953487
28 / 0     
Integrin alpha-IIb/beta-3 ITGA2B ITGB3 P08514 P05106 CHEMBL2093869 Membrane receptor 0.113285953487
143 / 0     
MAP kinase p38 alpha MAPK14 Q16539 CHEMBL260 Kinase 0.113285953487
33 / 0     
MAP kinase p38 beta MAPK11 Q15759 CHEMBL3961 Kinase 0.113285953487
1 / 0     
Opioid growth factor receptor-like protein 1 OGFRL1 Q5TC84 CHEMBL3638334 Unclassified protein 0.113285953487
16 / 0     
Thrombin and coagulation factor X F10 P00742 CHEMBL244 Protease 0.113285953487
18 / 0     
Cyclin-dependent kinase 9 CDK9 P50750 CHEMBL3116 Kinase 0.113285953487
10 / 0     
Adrenergic receptor beta ADRB2 P07550 CHEMBL210 Family A G protein-coupled receptor 0.113285953487
3 / 0     
Beta-1 adrenergic receptor ADRB1 P08588 CHEMBL213 Family A G protein-coupled receptor 0.113285953487
4 / 0     
Retinoid X receptor alpha RXRA P19793 CHEMBL2061 Nuclear receptor 0.113285953487
13 / 0     
Leukotriene B4 receptor 1 LTB4R Q15722 CHEMBL3911 Family A G protein-coupled receptor 0.113285953487
8 / 0     
Receptor-type tyrosine-protein phosphatase alpha PTPRA P18433 CHEMBL3918 Phosphatase 0.113285953487
2 / 0     
Inhibitor of apoptosis protein 3 XIAP P98170 CHEMBL4198 Other cytosolic protein 0.113285953487
9 / 0     
Tryptophan 5-hydroxylase 1 TPH1 P17752 CHEMBL5689 Enzyme 0.113285953487
40 / 0     
Sodium channel protein type IX alpha subunit SCN9A Q15858 CHEMBL4296 Voltage-gated ion channel 0.113285953487
1 / 0     
Carboxypeptidase B CPB1 P15086 CHEMBL2552 Protease 0.113285953487
11 / 0     
Endothelin receptor ET-B EDNRB P24530 CHEMBL1785 Family A G protein-coupled receptor 0.113285953487
80 / 0     
Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 P12268 CHEMBL2002 Oxidoreductase 0.113285953487
43 / 0     
Tyrosine-protein kinase SRC SRC P12931 CHEMBL267 Kinase 0.113285953487
25 / 0     
Squalene synthetase FDFT1 P37268 CHEMBL3338 Enzyme 0.0
9 / 0     
Inosine-5'-monophosphate dehydrogenase 1 IMPDH1 P20839 CHEMBL1822 Oxidoreductase 0.0
17 / 0     
Thromboxane A2 receptor TBXA2R P21731 CHEMBL2069 Family A G protein-coupled receptor 0.0
89 / 0     
Peroxisome proliferator-activated receptor gamma PPARG P37231 CHEMBL235 Nuclear receptor 0.0
38 / 0     
Insulin-degrading enzyme IDE P14735 CHEMBL1293287 Enzyme 0.0
6 / 0     
Thrombin F2 P00734 CHEMBL204 Protease 0.0
22 / 0     
NAD-dependent deacetylase sirtuin 1 SIRT1 Q96EB6 CHEMBL4506 Eraser 0.0
3 / 0     
Kinesin-like protein 1 KIF11 P52732 CHEMBL4581 Other cytosolic protein 0.0
60 / 0     
Probable G-protein coupled receptor 142 GPR142 Q7Z601 CHEMBL2069161 Family A G protein-coupled receptor 0.0
4 / 0     
C-C chemokine receptor type 3 CCR3 P51677 CHEMBL3473 Family A G protein-coupled receptor 0.0
33 / 0     
Histone deacetylase 1 HDAC1 Q13547 CHEMBL325 Eraser 0.0
5 / 0     
HMG-CoA reductase (by homology) HMGCR P04035 CHEMBL402 Oxidoreductase 0.0
279 / 0     
Muscarinic acetylcholine receptor M1 (by homology) CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0
1 / 0     
Autotaxin ENPP2 Q13822 CHEMBL3691 Enzyme 0.0
5 / 0     
Serine/threonine-protein kinase Chk1 CHEK1 O14757 CHEMBL4630 Kinase 0.0
7 / 0     
Serine/threonine-protein kinase WEE1 WEE1 P30291 CHEMBL5491 Kinase 0.0
4 / 0     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.0
3 / 0     
Serotonin 3a (5-HT3a) receptor (by homology) HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0
6 / 0     
Thyroid hormone receptor alpha THRA P10827 CHEMBL1860 Nuclear receptor 0.0
114 / 0     
Neprilysin MME P08473 CHEMBL1944 Protease 0.0
58 / 0     
Thyroid hormone receptor beta-1 THRB P10828 CHEMBL1947 Nuclear receptor 0.0
128 / 0     
Glutamate receptor ionotropic kainate 1 GRIK1 P39086 CHEMBL1918 Ligand-gated ion channel 0.0
26 / 0     
Beta-3 adrenergic receptor ADRB3 P13945 CHEMBL246 Family A G protein-coupled receptor 0.0
7 / 0     
Glutamate receptor ionotropic, AMPA 2 GRIA2 P42262 CHEMBL4016 Ligand-gated ion channel 0.0
16 / 0     
Disks large homolog 4 DLG4 P78352 CHEMBL5666 Unclassified protein 0.0
11 / 0     
MAP kinase signal-integrating kinase 2 MKNK2 Q9HBH9 CHEMBL4204 Kinase 0.0
6 / 0     
Caspase-1 CASP1 P29466 CHEMBL4801 Protease 0.0
52 / 0     
Lysine-specific demethylase 5C KDM5C P41229 CHEMBL2163176 Eraser 0.0
2 / 0     
Transthyretin TTR P02766 CHEMBL3194 Secreted protein 0.0
3 / 0     
Lysine-specific demethylase 5B KDM5B Q9UGL1 CHEMBL3774295 Eraser 0.0
2 / 0     
Lysine-specific demethylase 2B KDM2B Q8NHM5 CHEMBL3779760 Eraser 0.0
1 / 0     
Glycogen synthase kinase-3 beta GSK3B P49841 CHEMBL262 Kinase 0.0
32 / 0     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0
8 / 0     
Integrin alpha-V/beta-5 ITGB5 ITGAV P18084 P06756 CHEMBL2096675 Membrane receptor 0.0
34 / 0     
Integrin alpha-V/beta-1 ITGAV ITGB1 P06756 P05556 CHEMBL2111407 Membrane receptor 0.0
16 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.