In order to avoid security-related warning messages when switching to secured connection, you may want either to:

Click here to proceed.

Query Molecule
Target Classes
Top 15
Top 25
Top 50
All
Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.519923086957
308 / 161     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.112450964818
152 / 11     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.112450964818
233 / 36     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.103761755413
160 / 110     
Serine/threonine-protein kinase AKT AKT1 P31749 CHEMBL4282 Kinase 0.0690974435253
43 / 17     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0604245879294
12 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.0604245879294
10 / 0     
Serine/threonine-protein kinase PIM3 PIM3 Q86V86 CHEMBL5407 Kinase 0.0604245879294
5 / 0     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.0604245879294
52 / 0     
Gamma-amino-N-butyrate transaminase (by homology) ABAT P80404 CHEMBL2044 Transferase 0.0604245879294
7 / 0     
Neuronal acetylcholine receptor protein alpha-4 subunit CHRNA4 P43681 CHEMBL1882 Ligand-gated ion channel 0.0604245879294
38 / 0     
Thrombin F2 P00734 CHEMBL204 Protease 0.0604245879294
16 / 0     
Inhibitor of nuclear factor kappa B kinase beta subunit IKBKB O14920 CHEMBL1991 Kinase 0.0604245879294
23 / 0     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0604245879294
7 / 0     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.0604245879294
10 / 0     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0604245879294
158 / 0     
Huntingtin HTT P42858 CHEMBL5514 Unclassified protein 0.0604245879294
2 / 0     
Protein arginine N-methyltransferase 3 PRMT3 O60678 CHEMBL5891 Writer 0.0604245879294
3 / 0     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.0604245879294
299 / 0     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0604245879294
379 / 194     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.0604245879294
76 / 0     
Dipeptidyl peptidase VIII DPP8 Q6V1X1 CHEMBL4657 Protease 0.0604245879294
60 / 0     
Fibroblast activation protein alpha FAP Q12884 CHEMBL4683 Protease 0.0604245879294
14 / 0     
Dipeptidyl peptidase IX DPP9 Q86TI2 CHEMBL4793 Protease 0.0604245879294
42 / 0     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.0604245879294
28 / 0     
Serotonin 1f (5-HT1f) receptor HTR1F P30939 CHEMBL1805 Family A G protein-coupled receptor 0.0604245879294
12 / 0     
Nitric-oxide synthase, brain NOS1 P29475 CHEMBL3568 Enzyme 0.0604245879294
25 / 0     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.0604245879294
11 / 0     
Dihydropteridine reductase QDPR P09417 CHEMBL3730 Enzyme 0.0604245879294
6 / 0     
Rho-associated protein kinase 1 ROCK1 Q13464 CHEMBL3231 Kinase 0.0604245879294
15 / 0     
Protein arginine N-methyltransferase 6 PRMT6 Q96LA8 CHEMBL1275221 Writer 0.0604245879294
8 / 0     
Protein arginine N-methyltransferase 8 PRMT8 Q9NR22 CHEMBL3108648 Writer 0.0604245879294
7 / 0     
Protein-arginine N-methyltransferase 1 PRMT1 Q99873 CHEMBL5524 Writer 0.0604245879294
6 / 0     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.0604245879294
22 / 0     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.0604245879294
17 / 0     
Trace amine-associated receptor 5 TAAR5 O14804 CHEMBL3714046 Family A G protein-coupled receptor 0.0604245879294
1 / 0     
Trace amine-associated receptor 1 TAAR1 Q96RJ0 CHEMBL5857 Family A G protein-coupled receptor 0.0604245879294
9 / 0     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0604245879294
172 / 66     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.0604245879294
6 / 0     
Carbonic anhydrase IX CA9 Q16790 CHEMBL3594 Lyase 0.0604245879294
9 / 0     
C-C chemokine receptor type 5 CCR5 P51681 CHEMBL274 Family A G protein-coupled receptor 0.0604245879294
2 / 0     
Serine/threonine-protein kinase Chk1 CHEK1 O14757 CHEMBL4630 Kinase 0.0604245879294
14 / 0     
C-C motif chemokine 2 CCL2 P13500 CHEMBL1649052 Family A G protein-coupled receptor 0.0604245879294
3 / 0     
Protein kinase N2 PKN2 Q16513 CHEMBL3032 Kinase 0.0604245879294
4 / 0     
Protein kinase C epsilon PRKCE Q02156 CHEMBL3582 Kinase 0.0604245879294
12 / 0     
Ribosomal protein S6 kinase alpha 5 RPS6KA5 O75582 CHEMBL4237 Kinase 0.0604245879294
3 / 0     
Serine/threonine-protein kinase/endoribonuclease IRE1 ERN1 O75460 CHEMBL1163101 Enzyme 0.0604245879294
1 / 0     
Lysine-specific demethylase 4D-like KDM4E B2RXH2 CHEMBL1293226 Eraser 0.0604245879294
1 / 0     
Tankyrase-2 TNKS2 Q9H2K2 CHEMBL6154 Enzyme 0.0604245879294
1 / 0     
Cyclin-dependent kinase 2/cyclin A CDK2 CCNA1 CCNA2 P24941 P78396 P20248 CHEMBL2094128 Other cytosolic protein 0.0604245879294
2 / 0     
Cyclin-dependent kinase 2 CDK2 P24941 CHEMBL301 Kinase 0.0604245879294
4 / 0     
Adenylate cyclase type V ADCY5 O95622 CHEMBL3189 Enzyme 0.0604245879294
2 / 0     
Nischarin NISCH Q9Y2I1 CHEMBL3923 Other cytosolic protein 0.0604245879294
1 / 0     
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 P32297 CHEMBL3068 Ligand-gated ion channel 0.0604245879294
2 / 0     
Leucine aminopeptidase LAP3 P28838 CHEMBL3965 Protease 0.0604245879294
2 / 0     
Acetylcholine receptor protein alpha chain CHRNA1 P02708 CHEMBL4808 Ligand-gated ion channel 0.0604245879294
2 / 0     
NAD-dependent deacetylase sirtuin 1 SIRT1 Q96EB6 CHEMBL4506 Eraser 0.0604245879294
1 / 0     
Histone deacetylase 2 HDAC2 Q92769 CHEMBL1937 Eraser 0.0
1 / 0     
Histone deacetylase 8 HDAC8 Q9BY41 CHEMBL3192 Eraser 0.0
5 / 0     
Histone deacetylase 1 HDAC1 Q13547 CHEMBL325 Eraser 0.0
14 / 0     
Serine/threonine-protein kinase haspin HASPIN Q8TF76 CHEMBL1075163 Kinase 0.0
15 / 0     
Acetylcholine receptor; alpha1/beta1/delta/gamma CHRNB1 CHRNA1 CHRNG CHRND P11230 P02708 P07510 Q07001 CHEMBL1907588 Ligand-gated ion channel 0.0
3 / 0     
Melanocortin receptor 4 MC4R P32245 CHEMBL259 Family A G protein-coupled receptor 0.0
10 / 0     
Phosphodiesterase 10A PDE10A Q9Y233 CHEMBL4409 Phosphodiesterase 0.0
4 / 0     
PDZ-binding kinase PBK Q96KB5 CHEMBL4896 Kinase 0.0
3 / 0     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0
621 / 33     
Serotonin 3a (5-HT3a) receptor HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0
26 / 0     
Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial AADAT Q8N5Z0 CHEMBL2046259 Enzyme 0.0
37 / 0     
Dipeptidyl peptidase I CTSC P53634 CHEMBL2252 Protease 0.0
9 / 0     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.0
12 / 0     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0
21 / 0     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0
40 / 0     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0
13 / 0     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.0
7 / 0     
Aminopeptidase N ANPEP P15144 CHEMBL1907 Protease 0.0
8 / 0     
Indoleamine 2,3-dioxygenase IDO1 P14902 CHEMBL4685 Enzyme 0.0
2 / 0     
Dual specificity protein kinase TTK TTK P33981 CHEMBL3983 Kinase 0.0
3 / 0     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.0
33 / 0     
Carbonic anhydrase VII CA7 P43166 CHEMBL2326 Lyase 0.0
5 / 0     
Sodium channel protein type V alpha subunit SCN5A Q14524 CHEMBL1980 Voltage-gated ion channel 0.0
1 / 0     
Neurokinin 1 receptor (by homology) TACR1 P25103 CHEMBL249 Family A G protein-coupled receptor 0.0
20 / 0     
Sodium channel protein type II alpha subunit SCN2A Q99250 CHEMBL4187 Voltage-gated ion channel 0.0
1 / 0     
Phospholipase D1 PLD1 Q13393 CHEMBL2536 Hydrolase 0.0
1 / 0     
Protein kinase C delta PRKCD Q05655 CHEMBL2996 Kinase 0.0
11 / 0     
Protein kinase C eta PRKCH P24723 CHEMBL3616 Kinase 0.0
10 / 0     
Protein kinase C theta PRKCQ Q04759 CHEMBL3920 Kinase 0.0
13 / 0     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.0
78 / 11     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.0
49 / 1     
Lethal(3)malignant brain tumor-like protein 3 L3MBTL3 Q96JM7 CHEMBL1287623 Reader 0.0
3 / 0     
Protein kinase C beta PRKCB P05771 CHEMBL3045 Kinase 0.0
6 / 0     
Histone-arginine methyltransferase CARM1 CARM1 Q86X55 CHEMBL5406 Writer 0.0
2 / 0     
Ephrin type-B receptor 3 EPHB3 P54753 CHEMBL4901 Kinase 0.0
1 / 0     
Metastin receptor KISS1R Q969F8 CHEMBL5413 Family A G protein-coupled receptor 0.0
5 / 0     
Histone acetyltransferase PCAF KAT2B Q92831 CHEMBL5500 Writer 0.0
6 / 0     
Serine/threonine-protein kinase Nek1 NEK1 Q96PY6 CHEMBL5855 Kinase 0.0
15 / 0     
Inhibitor of apoptosis protein 3 XIAP P98170 CHEMBL4198 Other cytosolic protein 0.0
12 / 0     
Dual-specificity tyrosine-phosphorylation regulated kinase 2 DYRK2 Q92630 CHEMBL4376 Kinase 0.0
4 / 0     
Baculoviral IAP repeat-containing protein 2 BIRC2 Q13490 CHEMBL5462 Enzyme 0.0
5 / 0     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.0
12 / 0     
Protein kinase C alpha PRKCA P17252 CHEMBL299 Kinase 0.0
4 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.