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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.102879010863
1152 / 148     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0721804396226
1407 / 114     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.0619149311119
880 / 99     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.0414702990123
261 / 6     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.0312265582077
139 / 4     
Dopamine D2 receptor (by homology) DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0312265582077
1095 / 74     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0312265582077
389 / 50     
Metastin receptor KISS1R Q969F8 CHEMBL5413 Family A G protein-coupled receptor 0.0312265582077
5 / 0     
Serotonin 3a (5-HT3a) receptor HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0312265582077
67 / 0     
Protein arginine N-methyltransferase 6 PRMT6 Q96LA8 CHEMBL1275221 Writer 0.0312265582077
6 / 0     
Histone-arginine methyltransferase CARM1 CARM1 Q86X55 CHEMBL5406 Writer 0.0312265582077
2 / 0     
Neuronal acetylcholine receptor protein alpha-4 subunit CHRNA4 P43681 CHEMBL1882 Ligand-gated ion channel 0.0312265582077
74 / 0     
Sodium channel protein type V alpha subunit SCN5A Q14524 CHEMBL1980 Voltage-gated ion channel 0.0312265582077
1 / 0     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0312265582077
203 / 0     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.0312265582077
143 / 0     
Sodium channel protein type II alpha subunit SCN2A Q99250 CHEMBL4187 Voltage-gated ion channel 0.0312265582077
1 / 0     
Dipeptidyl peptidase IX DPP9 Q86TI2 CHEMBL4793 Protease 0.0312265582077
91 / 0     
Dihydropteridine reductase QDPR P09417 CHEMBL3730 Enzyme 0.0312265582077
6 / 0     
Acetylcholine receptor; alpha1/beta1/delta/gamma CHRNB1 CHRNA1 CHRNG CHRND P11230 P02708 P07510 Q07001 CHEMBL1907588 Ligand-gated ion channel 0.0312265582077
14 / 2     
Dopamine D5 receptor DRD5 P21918 CHEMBL1850 Family A G protein-coupled receptor 0.0312265582077
77 / 0     
Anti-estrogen binding site (AEBS) EBP Q15125 CHEMBL4931 Enzyme 0.0312265582077
3 / 0     
Indoleamine 2,3-dioxygenase IDO1 P14902 CHEMBL4685 Enzyme 0.0312265582077
2 / 0     
Serotonin 1f (5-HT1f) receptor HTR1F P30939 CHEMBL1805 Family A G protein-coupled receptor 0.0312265582077
41 / 0     
Bromodomain-containing protein 4 BRD4 O60885 CHEMBL1163125 Reader 0.0312265582077
7 / 0     
Neuronal acetylcholine receptor protein alpha-7 subunit CHRNA7 P36544 CHEMBL2492 Ligand-gated ion channel 0.0312265582077
174 / 1     
Ribosomal protein S6 kinase 1 RPS6KB1 P23443 CHEMBL4501 Kinase 0.0312265582077
5 / 0     
Serine/threonine-protein kinase Aurora-A AURKA O14965 CHEMBL4722 Kinase 0.0312265582077
11 / 0     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.0312265582077
6 / 0     
Phospholipase D1 PLD1 Q13393 CHEMBL2536 Hydrolase 0.0312265582077
15 / 0     
Rho-associated protein kinase 1 ROCK1 Q13464 CHEMBL3231 Kinase 0.0312265582077
59 / 0     
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 P32297 CHEMBL3068 Ligand-gated ion channel 0.0312265582077
12 / 0     
Hormone sensitive lipase LIPE Q05469 CHEMBL3590 Enzyme 0.0312265582077
1 / 0     
Calcium sensing receptor CASR P41180 CHEMBL1878 Family C G protein-coupled receptor 0.0312265582077
11 / 0     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.0312265582077
24 / 0     
Acyl coenzyme A:cholesterol acyltransferase CES1 P23141 CHEMBL2265 Enzyme 0.0312265582077
0 / 24     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.0312265582077
64 / 0     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.0312265582077
48 / 0     
Carboxylesterase 2 CES2 O00748 CHEMBL3180 Enzyme 0.0312265582077
0 / 29     
Tyrosine-protein kinase TYK2 TYK2 P29597 CHEMBL3553 Kinase 0.0312265582077
14 / 0     
Sodium channel protein type IV alpha subunit SCN4A P35499 CHEMBL2072 Voltage-gated ion channel 0.0
13 / 0     
PDZ-binding kinase PBK Q96KB5 CHEMBL4896 Kinase 0.0
14 / 0     
Rho-associated protein kinase ROCK2 ROCK1 O75116 Q13464 CHEMBL2111459 Kinase 0.0
39 / 0     
Poly [ADP-ribose] polymerase 2 PARP2 Q9UGN5 CHEMBL5366 Enzyme 0.0
14 / 0     
Phosphodiesterase 7A PDE7A Q13946 CHEMBL3012 Phosphodiesterase 0.0
5 / 0     
Serine/threonine-protein kinase haspin HASPIN Q8TF76 CHEMBL1075163 Kinase 0.0
15 / 0     
Nischarin NISCH Q9Y2I1 CHEMBL3923 Other cytosolic protein 0.0
1 / 0     
Serine/threonine-protein kinase Chk1 CHEK1 O14757 CHEMBL4630 Kinase 0.0
58 / 0     
Protein arginine N-methyltransferase 3 PRMT3 O60678 CHEMBL5891 Writer 0.0
4 / 0     
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Q9UIF9 CHEMBL3108642 Reader 0.0
1 / 0     
Nociceptin receptor OPRL1 P41146 CHEMBL2014 Family A G protein-coupled receptor 0.0
94 / 0     
Nitric-oxide synthase, brain NOS1 P29475 CHEMBL3568 Enzyme 0.0
102 / 0     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.0
19 / 0     
Melatonin receptor 1A MTNR1A P48039 CHEMBL1945 Family A G protein-coupled receptor 0.0
2 / 19     
Glutamate NMDA receptor; GRIN1/GRIN2B GRIN1 GRIN2B Q05586 Q13224 CHEMBL1907603 Ligand-gated ion channel 0.0
2 / 0     
Glutamate NMDA receptor; GRIN1/GRIN2A GRIN2A GRIN1 Q12879 Q05586 CHEMBL1907604 Ligand-gated ion channel 0.0
3 / 0     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0
60 / 0     
Protein arginine N-methyltransferase 8 PRMT8 Q9NR22 CHEMBL3108648 Writer 0.0
5 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.0
40 / 0     
Serine/threonine-protein kinase PIM3 PIM3 Q86V86 CHEMBL5407 Kinase 0.0
15 / 0     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.0
626 / 26     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.0
129 / 0     
Nuclear receptor subfamily 4 group A member 1 NR4A1 P22736 CHEMBL1293229 Nuclear receptor 0.0
1 / 0     
Cyclin-dependent kinase 9 CDK9 P50750 CHEMBL3116 Kinase 0.0
41 / 0     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.0
57 / 0     
Dual-specificity tyrosine-phosphorylation regulated kinase 2 DYRK2 Q92630 CHEMBL4376 Kinase 0.0
5 / 0     
Phosphodiesterase 10A PDE10A Q9Y233 CHEMBL4409 Phosphodiesterase 0.0
1 / 0     
Somatostatin receptor 3 SSTR3 P32745 CHEMBL2028 Family A G protein-coupled receptor 0.0
21 / 0     
Solute carrier family 22 member 2 SLC22A2 O15244 CHEMBL1743122 Electrochemical transporter 0.0
1 / 0     
Multidrug and toxin extrusion protein 1 SLC47A1 Q96FL8 CHEMBL1743126 Electrochemical transporter 0.0
1 / 0     
Serotonin 3 (5-HT3) receptor HTR3B HTR3A O95264 P46098 CHEMBL2111332 Ligand-gated ion channel 0.0
2 / 0     
Neuropeptide Y receptor type 5 NPY5R Q15761 CHEMBL4561 Family A G protein-coupled receptor 0.0
2 / 0     
Adenylate cyclase type V ADCY5 O95622 CHEMBL3189 Enzyme 0.0
2 / 0     
Lethal(3)malignant brain tumor-like protein 3 L3MBTL3 Q96JM7 CHEMBL1287623 Reader 0.0
11 / 0     
Cytochrome P450 1A2 CYP1A2 P05177 CHEMBL3356 Cytochrome P450 0.0
2 / 0     
Quinone reductase 2 NQO2 P16083 CHEMBL3959 Enzyme 0.0
7 / 0     
Tankyrase-2 TNKS2 Q9H2K2 CHEMBL6154 Enzyme 0.0
1 / 0     
Inhibitor of nuclear factor kappa B kinase beta subunit IKBKB O14920 CHEMBL1991 Kinase 0.0
27 / 0     
Tyrosine- and threonine-specific cdc2-inhibitory kinase PKMYT1 Q99640 CHEMBL3984 Kinase 0.0
1 / 0     
Gamma-amino-N-butyrate transaminase (by homology) ABAT P80404 CHEMBL2044 Transferase 0.0
9 / 0     
C-C motif chemokine 2 CCL2 P13500 CHEMBL1649052 Family A G protein-coupled receptor 0.0
3 / 0     
Myosin light chain kinase, smooth muscle MYLK Q15746 CHEMBL2428 Kinase 0.0
2 / 0     
Protein kinase C delta PRKCD Q05655 CHEMBL2996 Kinase 0.0
35 / 0     
Protein kinase N2 PKN2 Q16513 CHEMBL3032 Kinase 0.0
13 / 0     
Protein kinase N1 PKN1 Q16512 CHEMBL3384 Kinase 0.0
5 / 0     
Protein kinase C epsilon PRKCE Q02156 CHEMBL3582 Kinase 0.0
21 / 0     
Protein kinase C mu PRKD1 Q15139 CHEMBL3863 Kinase 0.0
5 / 0     
Ribosomal protein S6 kinase alpha 5 RPS6KA5 O75582 CHEMBL4237 Kinase 0.0
4 / 0     
Histone acetyltransferase PCAF KAT2B Q92831 CHEMBL5500 Writer 0.0
6 / 0     
Toll-like receptor (TLR7/TLR9) TLR9 Q9NR96 CHEMBL5804 Toll-like and Il-1 receptors 0.0
1 / 0     
Serine/threonine-protein kinase PRKX PRKX P51817 CHEMBL5818 Kinase 0.0
2 / 0     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.0
806 / 12     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.0
29 / 0     
Purine nucleoside phosphorylase PNP P00491 CHEMBL4338 Enzyme 0.0
1 / 0     
Tyrosine-protein kinase SYK SYK P43405 CHEMBL2599 Kinase 0.0
26 / 0     
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 MALT1 Q9UDY8 CHEMBL3632452 Hydrolase 0.0
3 / 0     
Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3 CHRNB3 CHRNA6 CHRNB2 CHRNA3 Q05901 Q15825 P17787 P32297 CHEMBL2109233 Ligand-gated ion channel 0.0
8 / 0     
Glycogen synthase kinase-3 beta GSK3B P49841 CHEMBL262 Kinase 0.0
4 / 0     
Rho GDP-dissociation inhibitor 1 ARHGDIA P52565 CHEMBL3638327 Unclassified protein 0.0
2 / 0     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0
549 / 58     
Histone deacetylase 2 HDAC2 Q92769 CHEMBL1937 Eraser 0.0
1 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.