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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.933517693876
241 / 28     
Dopamine D5 receptor DRD5 P21918 CHEMBL1850 Family A G protein-coupled receptor 0.933517693876
104 / 4     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.933517693876
416 / 94     
Dopamine D1 receptor (by homology) DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.933517693876
324 / 21     
Adrenergic receptor beta ADRB2 P07550 CHEMBL210 Family A G protein-coupled receptor 0.933517693876
9 / 5     
Beta-1 adrenergic receptor ADRB1 P08588 CHEMBL213 Family A G protein-coupled receptor 0.933517693876
24 / 7     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.933517693876
1228 / 55     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.933517693876
3083 / 118     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.933517693876
15 / 10     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.933517693876
691 / 9     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.933517693876
1322 / 46     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.933517693876
620 / 27     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.933517693876
242 / 9     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.933517693876
1122 / 29     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.933517693876
687 / 24     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.933517693876
691 / 83     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.933517693876
86 / 10     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.694263062179
473 / 98     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.419655646483
1186 / 15     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.379279628511
71 / 15     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.379279628511
51 / 14     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.330703494192
17 / 4     
C-X-C chemokine receptor type 3 CXCR3 P49682 CHEMBL4441 Family A G protein-coupled receptor 0.233887254578
51 / 55     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.120823671646
64 / 12     
Plectin PLEC Q15149 CHEMBL1293240 Unclassified protein 0.112748418065
1 / 1     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.112748418065
340 / 11     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.104671941128
174 / 9     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.104671941128
235 / 0     
Thrombin F2 P00734 CHEMBL204 Protease 0.104671941128
185 / 0     
MAP kinase p38 alpha MAPK14 Q16539 CHEMBL260 Kinase 0.104671941128
152 / 0     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.104671941128
109 / 0     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.104671941128
50 / 0     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.104671941128
30 / 2     
Rho-associated protein kinase ROCK2 ROCK1 O75116 Q13464 CHEMBL2111459 Kinase 0.104671941128
57 / 0     
Urotensin II receptor UTS2R Q9UKP6 CHEMBL3764 Family A G protein-coupled receptor 0.104671941128
94 / 0     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.104671941128
214 / 0     
Glycine transporter 1 SLC6A9 P48067 CHEMBL2337 Electrochemical transporter 0.104671941128
72 / 0     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.104671941128
1576 / 48     
Cannabinoid receptor 1 (by homology) CNR1 P21554 CHEMBL218 Family A G protein-coupled receptor 0.104671941128
118 / 0     
Cannabinoid receptor 2 (by homology) CNR2 P34972 CHEMBL253 Family A G protein-coupled receptor 0.104671941128
78 / 0     
Scavenger receptor class B member 1 SCARB1 Q8WTV0 CHEMBL1914272 Unclassified protein 0.104671941128
10 / 0     
Muscarinic acetylcholine receptor M3 (by homology) CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.104671941128
367 / 0     
Inhibitor of apoptosis protein 3 XIAP P98170 CHEMBL4198 Other cytosolic protein 0.104671941128
282 / 0     
Baculoviral IAP repeat-containing protein 2 BIRC2 Q13490 CHEMBL5462 Enzyme 0.104671941128
91 / 0     
Glutamate [NMDA] receptor subunit epsilon 2 GRIN2B Q13224 CHEMBL1904 Ligand-gated ion channel 0.104671941128
12 / 0     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.104671941128
108 / 0     
Voltage-gated T-type calcium channel alpha-1I subunit CACNA1I Q9P0X4 CHEMBL5558 Voltage-gated ion channel 0.104671941128
8 / 0     
Lethal(3)malignant brain tumor-like protein 3 L3MBTL3 Q96JM7 CHEMBL1287623 Reader 0.104671941128
15 / 0     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.104671941128
171 / 0     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.104671941128
253 / 0     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.104671941128
526 / 0     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.104671941128
1287 / 0     
Synaptic vesicular amine transporter (by homology) SLC18A2 Q05940 CHEMBL1893 Electrochemical transporter 0.104671941128
57 / 0     
Lanosterol synthase LSS P48449 CHEMBL3593 Enzyme 0.104671941128
28 / 0     
p53-binding protein Mdm-2 MDM2 Q00987 CHEMBL5023 Other nuclear protein 0.104671941128
101 / 0     
Dipeptidyl peptidase VIII DPP8 Q6V1X1 CHEMBL4657 Protease 0.104671941128
203 / 0     
Dipeptidyl peptidase IX DPP9 Q86TI2 CHEMBL4793 Protease 0.104671941128
139 / 0     
Glucocorticoid receptor NR3C1 P04150 CHEMBL2034 Nuclear receptor 0.104671941128
42 / 0     
Phospholipase D1 PLD1 Q13393 CHEMBL2536 Hydrolase 0.104671941128
61 / 0     
Phospholipase D2 PLD2 O14939 CHEMBL2734 Hydrolase 0.104671941128
56 / 0     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.104671941128
118 / 0     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.104671941128
136 / 0     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.104671941128
159 / 0     
Sodium channel protein type IV alpha subunit SCN4A P35499 CHEMBL2072 Voltage-gated ion channel 0.104671941128
14 / 0     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.104671941128
82 / 0     
C-C chemokine receptor type 5 CCR5 P51681 CHEMBL274 Family A G protein-coupled receptor 0.104671941128
234 / 0     
Cytochrome P450 1A2 CYP1A2 P05177 CHEMBL3356 Cytochrome P450 0.104671941128
3 / 0     
Tyrosine-protein kinase TYK2 TYK2 P29597 CHEMBL3553 Kinase 0.104671941128
22 / 0     
Beta-secretase 1 BACE1 P56817 CHEMBL4822 Protease 0.104671941128
94 / 0     
C-C chemokine receptor type 3 CCR3 P51677 CHEMBL3473 Family A G protein-coupled receptor 0.104671941128
222 / 0     
Cell division protein kinase 8 CDK8 P49336 CHEMBL5719 Kinase 0.104671941128
26 / 0     
GABA transporter 1 SLC6A1 P30531 CHEMBL1903 Electrochemical transporter 0.104671941128
1 / 0     
Serotonin transporter (by homology) SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.104671941128
2591 / 131     
Calcium sensing receptor CASR P41180 CHEMBL1878 Family C G protein-coupled receptor 0.104671941128
14 / 0     
Nuclear receptor subfamily 1 group D member 1 NR1D1 P20393 CHEMBL1961783 Nuclear receptor 0.104671941128
6 / 0     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.104671941128
264 / 0     
Geranylgeranyl transferase type I beta subunit PGGT1B P53609 CHEMBL4135 Enzyme 0.104671941128
10 / 0     
Voltage-gated potassium channel subunit Kv1.5 KCNA5 P22460 CHEMBL4306 Voltage-gated ion channel 0.104671941128
41 / 0     
Neuropeptide Y receptor type 5 NPY5R Q15761 CHEMBL4561 Family A G protein-coupled receptor 0.104671941128
46 / 0     
Serine/threonine-protein kinase Chk1 CHEK1 O14757 CHEMBL4630 Kinase 0.104671941128
156 / 0     
Voltage-gated potassium channel subunit Kv1.3 KCNA3 P22001 CHEMBL4633 Voltage-gated ion channel 0.104671941128
12 / 0     
Neuropeptide Y receptor type 1 NPY1R P25929 CHEMBL4777 Family A G protein-coupled receptor 0.104671941128
63 / 0     
Tyrosine-protein kinase SRC SRC P12931 CHEMBL267 Kinase 0.104671941128
93 / 0     
P-glycoprotein 1 ABCB1 P08183 CHEMBL4302 Primary active transporter 0.104671941128
72 / 0     
Voltage-gated T-type calcium channel alpha-1G subunit CACNA1G O43497 CHEMBL4641 Voltage-gated ion channel 0.104671941128
66 / 0     
Translocator protein (by homology) TSPO P30536 CHEMBL5742 Membrane receptor 0.104671941128
60 / 0     
Centromere-associated protein E CENPE Q02224 CHEMBL5870 Unclassified protein 0.104671941128
11 / 0     
MBT domain-containing protein 1 MBTD1 Q05BQ5 CHEMBL1287625 Reader 0.104671941128
2 / 0     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.104671941128
50 / 0     
Telomerase reverse transcriptase TERT O14746 CHEMBL2916 Enzyme 0.104671941128
15 / 0     
Fibroblast activation protein alpha FAP Q12884 CHEMBL4683 Protease 0.104671941128
38 / 0     
Phenylethanolamine N-methyltransferase PNMT P11086 CHEMBL4617 Enzyme 0.104671941128
11 / 0     
Nucleotide-binding oligomerization domain-containing protein 1 NOD1 Q9Y239 CHEMBL1293222 Unclassified protein 0.104671941128
12 / 0     
Nucleotide-binding oligomerization domain-containing protein 2 NOD2 Q9HC29 CHEMBL1293266 Unclassified protein 0.104671941128
11 / 0     
Trypsin I PRSS1 P07477 CHEMBL209 Protease 0.104671941128
22 / 0     
Vascular endothelial growth factor receptor 2 KDR P35968 CHEMBL279 Kinase 0.104671941128
160 / 0     
Cyclin-dependent kinase 1 CDK1 P06493 CHEMBL308 Kinase 0.104671941128
56 / 0     
Monoamine oxidase A MAOA P21397 CHEMBL1951 Oxidoreductase 0.104671941128
66 / 0     
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 0.104671941128
63 / 0     
Melanin-concentrating hormone receptor 1 MCHR1 Q99705 CHEMBL344 Family A G protein-coupled receptor 0.104671941128
206 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.