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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.0414702990123
289 / 706     
Voltage-gated potassium channel subunit Kv1.5 KCNA5 P22460 CHEMBL4306 Voltage-gated ion channel 0.0414702990123
18 / 5     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.0414702990123
342 / 238     
Sigma opioid receptor (by homology) SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0414702990123
101 / 185     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0312265582077
381 / 622     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0312265582077
78 / 93     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0312265582077
70 / 154     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.0312265582077
143 / 113     
Delta opioid receptor OPRD1 P41143 CHEMBL236 Family A G protein-coupled receptor 0.0312265582077
114 / 54     
Neurokinin 1 receptor TACR1 P25103 CHEMBL249 Family A G protein-coupled receptor 0.0312265582077
7 / 331     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.0312265582077
86 / 42     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0312265582077
81 / 98     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0312265582077
52 / 83     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.0312265582077
44 / 11     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0312265582077
120 / 133     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.0312265582077
29 / 66     
ALK tyrosine kinase receptor ALK Q9UM73 CHEMBL4247 Kinase 0.0
4 / 0     
Mas-related G-protein coupled receptor member X1 MRGPRX1 Q96LB2 CHEMBL5850 Unclassified protein 0.0
0 / 2     
Serotonin 3a (5-HT3a) receptor HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0
9 / 0     
Polyadenylate-binding protein 1 PABPC1 P11940 CHEMBL1293286 Unclassified protein 0.0
0 / 3     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.0
21 / 32     
Serine/threonine-protein kinase Chk1 CHEK1 O14757 CHEMBL4630 Kinase 0.0
19 / 0     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.0
34 / 0     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.0
63 / 0     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.0
54 / 0     
Tyrosine-protein kinase TYK2 TYK2 P29597 CHEMBL3553 Kinase 0.0
28 / 0     
Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3 CHRNB3 CHRNA6 CHRNB2 CHRNA3 Q05901 Q15825 P17787 P32297 CHEMBL2109233 Ligand-gated ion channel 0.0
3 / 0     
Vesicular acetylcholine transporter SLC18A3 Q16572 CHEMBL4767 Electrochemical transporter 0.0
30 / 48     
Cytochrome P450 51 CYP51A1 Q16850 CHEMBL3849 Cytochrome P450 0.0
4 / 0     
Bromodomain adjacent to zinc finger domain protein 2B BAZ2B Q9UIF8 CHEMBL1741220 Reader 0.0
5 / 0     
Carbonic anhydrase II CA2 P00918 CHEMBL205 Lyase 0.0
37 / 0     
Carbonic anhydrase I CA1 P00915 CHEMBL261 Lyase 0.0
34 / 0     
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Q9UIF9 CHEMBL3108642 Reader 0.0
5 / 0     
Neuronal acetylcholine receptor; alpha2/beta4 CHRNB4 CHRNA2 P30926 Q15822 CHEMBL2109230 Ligand-gated ion channel 0.0
1 / 0     
Neuronal acetylcholine receptor; alpha3/beta2 CHRNA3 CHRNB2 P32297 P17787 CHEMBL2109234 Ligand-gated ion channel 0.0
1 / 0     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.0
23 / 0     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.0
31 / 7     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0
58 / 27     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.0
34 / 68     
CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase) CDC7 O00311 CHEMBL5443 Kinase 0.0
5 / 0     
Carbonic anhydrase VII CA7 P43166 CHEMBL2326 Lyase 0.0
13 / 0     
Carbonic anhydrase III CA3 P07451 CHEMBL2885 Lyase 0.0
2 / 0     
Carbonic anhydrase VI CA6 P23280 CHEMBL3025 Lyase 0.0
13 / 0     
Carbonic anhydrase XII CA12 O43570 CHEMBL3242 Lyase 0.0
17 / 0     
Carbonic anhydrase XIV CA14 Q9ULX7 CHEMBL3510 Lyase 0.0
10 / 0     
Carbonic anhydrase IX CA9 Q16790 CHEMBL3594 Lyase 0.0
24 / 0     
Carbonic anhydrase IV CA4 P22748 CHEMBL3729 Lyase 0.0
13 / 0     
Carbonic anhydrase XIII CA13 Q8N1Q1 CHEMBL3912 Lyase 0.0
15 / 0     
Carbonic anhydrase VB CA5B Q9Y2D0 CHEMBL3969 Lyase 0.0
8 / 0     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.0
23 / 43     
Androgen Receptor (by homology) AR P10275 CHEMBL1871 Nuclear receptor 0.0
76 / 0     
Phosphodiesterase 7A PDE7A Q13946 CHEMBL3012 Phosphodiesterase 0.0
3 / 0     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0
21 / 0     
Vanilloid receptor TRPV1 Q8NER1 CHEMBL4794 Voltage-gated ion channel 0.0
5 / 0     
Metastin receptor KISS1R Q969F8 CHEMBL5413 Family A G protein-coupled receptor 0.0
5 / 0     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.0
20 / 11     
Cytochrome P450 19A1 CYP19A1 P11511 CHEMBL1978 Cytochrome P450 0.0
35 / 0     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.0
5 / 0     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.0
9 / 0     
Cyclin-dependent kinase 5/CDK5 activator 1 CDK5R1 CDK5 Q15078 Q00535 CHEMBL1907600 Kinase 0.0
14 / 0     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0
24 / 0     
Serine/threonine-protein kinase PIM3 PIM3 Q86V86 CHEMBL5407 Kinase 0.0
14 / 0     
Rho-associated protein kinase ROCK2 ROCK1 O75116 Q13464 CHEMBL2111459 Kinase 0.0
2 / 0     
Proteinase activated receptor 4 F2RL3 Q96RI0 CHEMBL4691 Family A G protein-coupled receptor 0.0
1 / 0     
Heme oxygenase 1 (by homology) HMOX1 P09601 CHEMBL2823 Enzyme 0.0
6 / 0     
Adenosine deaminase ADA P00813 CHEMBL1910 Hydrolase 0.0
6 / 0     
Cytochrome P450 11B1 CYP11B1 P15538 CHEMBL1908 Cytochrome P450 0.0
8 / 0     
MAP kinase p38 alpha MAPK14 Q16539 CHEMBL260 Kinase 0.0
24 / 0     
Cytochrome P450 11B2 CYP11B2 P19099 CHEMBL2722 Cytochrome P450 0.0
8 / 0     
Neuronal acetylcholine receptor protein alpha-7 subunit CHRNA7 P36544 CHEMBL2492 Ligand-gated ion channel 0.0
26 / 13     
Cyclin-dependent kinase 1/cyclin B CCNB3 CDK1 CCNB1 CCNB2 Q8WWL7 P06493 P14635 O95067 CHEMBL2094127 Other cytosolic protein 0.0
4 / 0     
Glycogen synthase kinase-3 beta GSK3B P49841 CHEMBL262 Kinase 0.0
22 / 0     
Phosphodiesterase 10A PDE10A Q9Y233 CHEMBL4409 Phosphodiesterase 0.0
52 / 0     
Cytochrome P450 1A2 CYP1A2 P05177 CHEMBL3356 Cytochrome P450 0.0
1 / 0     
Mitogen-activated protein kinase kinase kinase 14 MAP3K14 Q99558 CHEMBL5888 Kinase 0.0
2 / 0     
Vascular endothelial growth factor receptor 2 KDR P35968 CHEMBL279 Kinase 0.0
82 / 0     
Glutamate NMDA receptor; GRIN1/GRIN2A GRIN2A GRIN1 Q12879 Q05586 CHEMBL1907604 Ligand-gated ion channel 0.0
0 / 2     
GABA transporter 1 SLC6A1 P30531 CHEMBL1903 Electrochemical transporter 0.0
0 / 13     
dUTP pyrophosphatase DUT P33316 CHEMBL5203 Enzyme 0.0
21 / 0     
Transient receptor potential cation channel subfamily V member 3 TRPV3 Q8NET8 CHEMBL5522 Voltage-gated ion channel 0.0
33 / 0     
Nociceptin receptor OPRL1 P41146 CHEMBL2014 Family A G protein-coupled receptor 0.0
27 / 25     
Interleukin-8 receptor B CXCR2 P25025 CHEMBL2434 Family A G protein-coupled receptor 0.0
30 / 0     
Isoprenylcysteine carboxyl methyltransferase ICMT O60725 CHEMBL4699 Enzyme 0.0
2 / 0     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.0
33 / 35     
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Q5S007 CHEMBL1075104 Kinase 0.0
51 / 0     
Progesterone receptor PGR P06401 CHEMBL208 Nuclear receptor 0.0
18 / 0     
Glucocorticoid receptor NR3C1 P04150 CHEMBL2034 Nuclear receptor 0.0
32 / 0     
3-phosphoinositide dependent protein kinase-1 PDPK1 O15530 CHEMBL2534 Kinase 0.0
9 / 0     
Methionine aminopeptidase 1 METAP1 P53582 CHEMBL2474 Protease 0.0
2 / 0     
ADAM17 ADAM17 P78536 CHEMBL3706 Protease 0.0
5 / 0     
11-beta-hydroxysteroid dehydrogenase 1 HSD11B1 P28845 CHEMBL4235 Enzyme 0.0
24 / 0     
JAK3/JAK1 JAK3 JAK1 P52333 P23458 CHEMBL3038491 Kinase 0.0
1 / 0     
Toll-like receptor 8 TLR8 Q9NR97 CHEMBL5805 Toll-like and Il-1 receptors 0.0
3 / 0     
Toll-like receptor (TLR7/TLR9) TLR7 Q9NYK1 CHEMBL5936 Toll-like and Il-1 receptors 0.0
4 / 0     
Sulfonylurea receptor 2 ABCC9 O60706 CHEMBL1971 Primary active transporter 0.0
21 / 0     
MAP kinase ERK2 MAPK1 P28482 CHEMBL4040 Kinase 0.0
46 / 0     
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Q02750 CHEMBL3587 Kinase 0.0
10 / 0     
Mineralocorticoid receptor NR3C2 P08235 CHEMBL1994 Nuclear receptor 0.0
9 / 0     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.0
6 / 0     
Prostaglandin E synthase PTGES O14684 CHEMBL5658 Enzyme 0.0
4 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.