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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.418442930291
740 / 355     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.418442930291
1543 / 554     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.418442930291
1419 / 797     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.119895126898
1544 / 347     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.112041901328
534 / 179     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.112041901328
632 / 137     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.112041901328
844 / 280     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.112041901328
155 / 70     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.112041901328
126 / 19     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.112041901328
41 / 8     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.112041901328
206 / 0     
Neuronal acetylcholine receptor protein alpha-4 subunit CHRNA4 P43681 CHEMBL1882 Ligand-gated ion channel 0.112041901328
23 / 0     
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 P32297 CHEMBL3068 Ligand-gated ion channel 0.112041901328
9 / 0     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.112041901328
341 / 67     
Melanin-concentrating hormone receptor 1 MCHR1 Q99705 CHEMBL344 Family A G protein-coupled receptor 0.112041901328
51 / 43     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.112041901328
664 / 94     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.112041901328
712 / 553     
Delta opioid receptor OPRD1 P41143 CHEMBL236 Family A G protein-coupled receptor 0.112041901328
461 / 437     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.112041901328
549 / 271     
Serotonin 1f (5-HT1f) receptor HTR1F P30939 CHEMBL1805 Family A G protein-coupled receptor 0.112041901328
58 / 0     
Sodium channel protein type IV alpha subunit SCN4A P35499 CHEMBL2072 Voltage-gated ion channel 0.112041901328
11 / 0     
Choline kinase alpha CHKA P35790 CHEMBL3117 Enzyme 0.112041901328
3 / 0     
C-X-C chemokine receptor type 3 CXCR3 P49682 CHEMBL4441 Family A G protein-coupled receptor 0.112041901328
22 / 0     
Translocator protein (by homology) TSPO P30536 CHEMBL5742 Membrane receptor 0.112041901328
37 / 0     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.112041901328
114 / 0     
Telomerase reverse transcriptase TERT O14746 CHEMBL2916 Enzyme 0.112041901328
14 / 0     
Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3 CHRNB3 CHRNA6 CHRNB2 CHRNA3 Q05901 Q15825 P17787 P32297 CHEMBL2109233 Ligand-gated ion channel 0.112041901328
4 / 0     
Nuclear receptor subfamily 1 group D member 1 NR1D1 P20393 CHEMBL1961783 Nuclear receptor 0.112041901328
6 / 0     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.112041901328
326 / 25     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.112041901328
362 / 45     
Rho-associated protein kinase ROCK2 ROCK1 O75116 Q13464 CHEMBL2111459 Kinase 0.112041901328
44 / 0     
Transient receptor potential cation channel subfamily M member 8 (by homology) TRPM8 Q7Z2W7 CHEMBL1075319 Voltage-gated ion channel 0.112041901328
21 / 0     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.112041901328
17 / 0     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.112041901328
37 / 0     
Rho-associated protein kinase 1 ROCK1 Q13464 CHEMBL3231 Kinase 0.112041901328
32 / 0     
Interleukin-1 receptor-associated kinase 4 IRAK4 Q9NWZ3 CHEMBL3778 Kinase 0.112041901328
27 / 0     
Transient receptor potential cation channel subfamily A member 1 TRPA1 O75762 CHEMBL6007 Voltage-gated ion channel 0.112041901328
3 / 0     
MAP kinase p38 alpha MAPK14 Q16539 CHEMBL260 Kinase 0.112041901328
22 / 0     
Acetylcholine receptor; alpha1/beta1/delta/gamma CHRNB1 CHRNA1 CHRNG CHRND P11230 P02708 P07510 Q07001 CHEMBL1907588 Ligand-gated ion channel 0.112041901328
7 / 2     
Solute carrier family 22 member 2 SLC22A2 O15244 CHEMBL1743122 Electrochemical transporter 0.112041901328
1 / 0     
Multidrug and toxin extrusion protein 1 SLC47A1 Q96FL8 CHEMBL1743126 Electrochemical transporter 0.112041901328
2 / 0     
Serotonin 3 (5-HT3) receptor HTR3B HTR3A O95264 P46098 CHEMBL2111332 Ligand-gated ion channel 0.112041901328
2 / 0     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.112041901328
186 / 8     
Nitric-oxide synthase, brain NOS1 P29475 CHEMBL3568 Enzyme 0.112041901328
63 / 0     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.112041901328
42 / 0     
Calcium sensing receptor CASR P41180 CHEMBL1878 Family C G protein-coupled receptor 0.0
12 / 0     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0
125 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.0
96 / 0     
TGF-beta receptor type I TGFBR1 P36897 CHEMBL4439 Kinase 0.0
11 / 0     
Metabotropic glutamate receptor 2 (by homology) GRM2 Q14416 CHEMBL5137 Family C G protein-coupled receptor 0.0
1 / 0     
PH domain leucine-rich repeat-containing protein phosphatase 2 PHLPP2 Q6ZVD8 CHEMBL1275209 Enzyme 0.0
2 / 0     
Phospholipase D1 PLD1 Q13393 CHEMBL2536 Hydrolase 0.0
34 / 0     
Rho GDP-dissociation inhibitor 1 ARHGDIA P52565 CHEMBL3638327 Unclassified protein 0.0
3 / 0     
Glucagon-like peptide 1 receptor GLP1R P43220 CHEMBL1784 Family B G protein-coupled receptor 0.0
3 / 0     
Tyrosine-protein kinase receptor FLT3 FLT3 P36888 CHEMBL1974 Kinase 0.0
20 / 0     
Somatostatin receptor 3 SSTR3 P32745 CHEMBL2028 Family A G protein-coupled receptor 0.0
29 / 0     
Scavenger receptor class B member 1 SCARB1 Q8WTV0 CHEMBL1914272 Unclassified protein 0.0
2 / 0     
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Q12791 CHEMBL4304 Voltage-gated ion channel 0.0
1 / 0     
Cholecystokinin A receptor (by homology) CCKAR P32238 CHEMBL1901 Family A G protein-coupled receptor 0.0
1 / 0     
Glutamate receptor ionotropic kainate 1 GRIK1 P39086 CHEMBL1918 Ligand-gated ion channel 0.0
0 / 3     
Serine/threonine-protein kinase AKT AKT1 P31749 CHEMBL4282 Kinase 0.0
14 / 0     
Phosphodiesterase 8B PDE8B O95263 CHEMBL4408 Phosphodiesterase 0.0
3 / 0     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0
289 / 61     
Transcriptional regulator ERG ERG P11308 CHEMBL1293191 Unclassified protein 0.0
7 / 0     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.0
10 / 0     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.0
5 / 0     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.0
43 / 0     
Tyrosine-protein kinase TYK2 TYK2 P29597 CHEMBL3553 Kinase 0.0
11 / 0     
Thymidine kinase, cytosolic TK1 P04183 CHEMBL2883 Transferase 0.0
1 / 0     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.0
24 / 0     
PDZ-binding kinase PBK Q96KB5 CHEMBL4896 Kinase 0.0
6 / 0     
Vesicular acetylcholine transporter SLC18A3 Q16572 CHEMBL4767 Electrochemical transporter 0.0
7 / 41     
Thyroid hormone receptor alpha THRA P10827 CHEMBL1860 Nuclear receptor 0.0
2 / 12     
Thyroid hormone receptor beta-1 THRB P10828 CHEMBL1947 Nuclear receptor 0.0
1 / 13     
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 HCN4 Q9Y3Q4 CHEMBL1250417 Voltage-gated ion channel 0.0
7 / 0     
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 HCN1 O60741 CHEMBL1795171 Voltage-gated ion channel 0.0
8 / 0     
Focal adhesion kinase 1 PTK2 Q05397 CHEMBL2695 Kinase 0.0
2 / 0     
C-C chemokine receptor type 5 CCR5 P51681 CHEMBL274 Family A G protein-coupled receptor 0.0
25 / 77     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.0
39 / 5     
Cyclin-dependent kinase 1/cyclin B1 CDK1 CCNB1 P06493 P14635 CHEMBL1907602 Other cytosolic protein 0.0
3 / 0     
Cyclin-dependent kinase 5/CDK5 activator 1 CDK5R1 CDK5 Q15078 Q00535 CHEMBL1907600 Kinase 0.0
4 / 0     
Quinone reductase 1 NQO1 P15559 CHEMBL3623 Enzyme 0.0
5 / 0     
Hepatocyte growth factor receptor MET P08581 CHEMBL3717 Kinase 0.0
24 / 0     
Serine/threonine-protein kinase haspin HASPIN Q8TF76 CHEMBL1075163 Kinase 0.0
4 / 0     
Lethal(3)malignant brain tumor-like protein 1 L3MBTL1 Q9Y468 CHEMBL1287622 Reader 0.0
3 / 0     
MBT domain-containing protein 1 MBTD1 Q05BQ5 CHEMBL1287625 Reader 0.0
2 / 0     
Platelet-derived growth factor receptor beta PDGFRB P09619 CHEMBL1913 Kinase 0.0
8 / 0     
MAP kinase-activated protein kinase 2 MAPKAPK2 P49137 CHEMBL2208 Kinase 0.0
5 / 0     
Phospholipase D2 PLD2 O14939 CHEMBL2734 Hydrolase 0.0
28 / 0     
Vascular endothelial growth factor receptor 2 KDR P35968 CHEMBL279 Kinase 0.0
20 / 0     
Fibroblast growth factor receptor 1 FGFR1 P11362 CHEMBL3650 Kinase 0.0
8 / 0     
Ubiquitin carboxyl-terminal hydrolase 14 USP14 P54578 CHEMBL1293295 Enzyme 0.0
1 / 0     
DNA-directed RNA polymerase I subunit RPA1 POLR1A O95602 CHEMBL3286067 Enzyme 0.0
3 / 0     
3-phosphoinositide dependent protein kinase-1 PDPK1 O15530 CHEMBL2534 Kinase 0.0
2 / 0     
Cyclin-dependent kinase 2 CDK2 P24941 CHEMBL301 Kinase 0.0
7 / 0     
Sphingosine kinase 1 SPHK1 Q9NYA1 CHEMBL4394 Enzyme 0.0
0 / 10     
Androgen Receptor AR P10275 CHEMBL1871 Nuclear receptor 0.0
2 / 0     
Mineralocorticoid receptor NR3C2 P08235 CHEMBL1994 Nuclear receptor 0.0
3 / 0     
Progesterone receptor PGR P06401 CHEMBL208 Nuclear receptor 0.0
9 / 0     
GABA-A receptor; alpha-1/beta-3/gamma-2 GABRB3 GABRG2 GABRA1 P28472 P18507 P14867 CHEMBL2094121 Ligand-gated ion channel 0.0
4 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.