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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.119895126898
593 / 573     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.119895126898
109 / 81     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.112041901328
611 / 471     
Glutamate NMDA receptor; GRIN1/GRIN2A GRIN2A GRIN1 Q12879 Q05586 CHEMBL1907604 Ligand-gated ion channel 0.112041901328
4 / 11     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.112041901328
320 / 461     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.112041901328
437 / 710     
Delta opioid receptor OPRD1 P41143 CHEMBL236 Family A G protein-coupled receptor 0.112041901328
292 / 523     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.112041901328
490 / 189     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.112041901328
502 / 525     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.112041901328
8 / 359     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.112041901328
289 / 455     
PH domain leucine-rich repeat-containing protein phosphatase 2 PHLPP2 Q6ZVD8 CHEMBL1275209 Enzyme 0.112041901328
1 / 0     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.112041901328
82 / 220     
Vanilloid receptor (by homology) TRPV1 Q8NER1 CHEMBL4794 Voltage-gated ion channel 0.112041901328
0 / 46     
Neurokinin 1 receptor TACR1 P25103 CHEMBL249 Family A G protein-coupled receptor 0.112041901328
53 / 228     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.112041901328
9 / 0     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.112041901328
34 / 23     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.112041901328
215 / 248     
Indoleamine 2,3-dioxygenase IDO1 P14902 CHEMBL4685 Enzyme 0.112041901328
2 / 0     
Neuropeptide Y receptor type 1 NPY1R P25929 CHEMBL4777 Family A G protein-coupled receptor 0.112041901328
14 / 49     
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 0.112041901328
35 / 20     
Lysine-specific histone demethylase 1 KDM1A O60341 CHEMBL6136 Eraser 0.112041901328
56 / 42     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.112041901328
60 / 83     
Serine/threonine-protein kinase haspin HASPIN Q8TF76 CHEMBL1075163 Kinase 0.112041901328
15 / 0     
Hematopoietic prostaglandin D synthase HPGDS O60760 CHEMBL5879 Transferase 0.112041901328
1 / 0     
Neuronal acetylcholine receptor protein alpha-4 subunit CHRNA4 P43681 CHEMBL1882 Ligand-gated ion channel 0.112041901328
22 / 0     
Nitric-oxide synthase, brain NOS1 P29475 CHEMBL3568 Enzyme 0.112041901328
19 / 0     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.112041901328
65 / 200     
Cannabinoid receptor 1 CNR1 P21554 CHEMBL218 Family A G protein-coupled receptor 0.112041901328
0 / 121     
Cannabinoid receptor 2 CNR2 P34972 CHEMBL253 Family A G protein-coupled receptor 0.112041901328
0 / 135     
Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3 CHRNB3 CHRNA6 CHRNB2 CHRNA3 Q05901 Q15825 P17787 P32297 CHEMBL2109233 Ligand-gated ion channel 0.112041901328
4 / 0     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.112041901328
10 / 7     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.112041901328
10 / 19     
Monoamine oxidase A MAOA P21397 CHEMBL1951 Oxidoreductase 0.112041901328
34 / 20     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.112041901328
50 / 38     
Calcium sensing receptor CASR P41180 CHEMBL1878 Family C G protein-coupled receptor 0.112041901328
7 / 18     
Sodium channel protein type IV alpha subunit SCN4A P35499 CHEMBL2072 Voltage-gated ion channel 0.112041901328
13 / 0     
Rho-associated protein kinase 1 ROCK1 Q13464 CHEMBL3231 Kinase 0.112041901328
19 / 0     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.112041901328
18 / 19     
Protein tyrosine phosphatase receptor type C-associated protein PTPRCAP Q14761 CHEMBL4806 Enzyme 0.112041901328
1 / 0     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.112041901328
282 / 89     
Acetylcholine receptor; alpha1/beta1/delta/gamma CHRNB1 CHRNA1 CHRNG CHRND P11230 P02708 P07510 Q07001 CHEMBL1907588 Ligand-gated ion channel 0.112041901328
7 / 0     
Melatonin receptor 1B MTNR1B P49286 CHEMBL1946 Family A G protein-coupled receptor 0.112041901328
5 / 102     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.112041901328
107 / 65     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.112041901328
42 / 95     
Beta-secretase 1 BACE1 P56817 CHEMBL4822 Protease 0.112041901328
0 / 93     
Serotonin 5a (5-HT5a) receptor (by homology) HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.112041901328
34 / 19     
Cyclin-dependent kinase 9 CDK9 P50750 CHEMBL3116 Kinase 0.112041901328
20 / 0     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.112041901328
6 / 95     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.112041901328
333 / 136     
Serotonin 1f (5-HT1f) receptor HTR1F P30939 CHEMBL1805 Family A G protein-coupled receptor 0.112041901328
18 / 0     
Tankyrase-2 TNKS2 Q9H2K2 CHEMBL6154 Enzyme 0.112041901328
1 / 0     
Serine/threonine-protein kinase PRKX PRKX P51817 CHEMBL5818 Kinase 0.112041901328
1 / 0     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.112041901328
18 / 26     
Synaptic vesicular amine transporter (by homology) SLC18A2 Q05940 CHEMBL1893 Electrochemical transporter 0.112041901328
7 / 126     
Rho-associated protein kinase ROCK2 ROCK1 O75116 Q13464 CHEMBL2111459 Kinase 0.112041901328
17 / 0     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.112041901328
299 / 227     
Myosin light chain kinase, smooth muscle MYLK Q15746 CHEMBL2428 Kinase 0.112041901328
1 / 0     
Protein kinase N1 PKN1 Q16512 CHEMBL3384 Kinase 0.112041901328
1 / 0     
Protein kinase C epsilon PRKCE Q02156 CHEMBL3582 Kinase 0.112041901328
5 / 0     
Ribosomal protein S6 kinase alpha 5 RPS6KA5 O75582 CHEMBL4237 Kinase 0.112041901328
2 / 0     
Toll-like receptor (TLR7/TLR9) TLR9 Q9NR96 CHEMBL5804 Toll-like and Il-1 receptors 0.112041901328
1 / 0     
Nuclear receptor subfamily 4 group A member 1 NR4A1 P22736 CHEMBL1293229 Nuclear receptor 0.0
1 / 0     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.0
4 / 0     
FK506-binding protein 1A FKBP1A P62942 CHEMBL1902 Isomerase 0.0
0 / 58     
Peptidyl-prolyl cis-trans isomerase FKBP5 FKBP5 Q13451 CHEMBL2052031 Enzyme 0.0
0 / 26     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.0
112 / 34     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0
8 / 5     
Plectin PLEC Q15149 CHEMBL1293240 Unclassified protein 0.0
2 / 0     
P-glycoprotein 1 ABCB1 P08183 CHEMBL4302 Primary active transporter 0.0
7 / 51     
Tyrosine-protein kinase receptor FLT3 FLT3 P36888 CHEMBL1974 Kinase 0.0
7 / 0     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.0
15 / 0     
Prion protein PRNP P04156 CHEMBL4869 Surface antigen 0.0
1 / 0     
Sphingosine kinase 2 SPHK2 Q9NRA0 CHEMBL3023 Enzyme 0.0
0 / 7     
Sphingosine kinase 1 SPHK1 Q9NYA1 CHEMBL4394 Enzyme 0.0
0 / 4     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.0
120 / 17     
C-C chemokine receptor type 3 CCR3 P51677 CHEMBL3473 Family A G protein-coupled receptor 0.0
0 / 34     
Glycine transporter 1 SLC6A9 P48067 CHEMBL2337 Electrochemical transporter 0.0
5 / 24     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0
21 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.0
20 / 0     
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Q5S007 CHEMBL1075104 Kinase 0.0
1 / 0     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.0
86 / 4     
Trace amine-associated receptor 1 (by homology) TAAR1 Q96RJ0 CHEMBL5857 Family A G protein-coupled receptor 0.0
1 / 0     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0
174 / 35     
Dual-specificity tyrosine-phosphorylation regulated kinase 2 DYRK2 Q92630 CHEMBL4376 Kinase 0.0
4 / 0     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0
2 / 1     
Nuclear receptor subfamily 1 group D member 1 NR1D1 P20393 CHEMBL1961783 Nuclear receptor 0.0
2 / 0     
Voltage-gated potassium channel subunit Kv1.5 KCNA5 P22460 CHEMBL4306 Voltage-gated ion channel 0.0
2 / 0     
Neuronal acetylcholine receptor; alpha3/beta2 CHRNA3 CHRNB2 P32297 P17787 CHEMBL2109234 Ligand-gated ion channel 0.0
4 / 0     
c-Jun N-terminal kinase 1 MAPK8 P45983 CHEMBL2276 Kinase 0.0
1 / 0     
Amine oxidase, copper containing AOC3 Q16853 CHEMBL3437 Enzyme 0.0
5 / 0     
Metastin receptor KISS1R Q969F8 CHEMBL5413 Family A G protein-coupled receptor 0.0
5 / 0     
Protein kinase C theta PRKCQ Q04759 CHEMBL3920 Kinase 0.0
8 / 0     
Nociceptin receptor OPRL1 P41146 CHEMBL2014 Family A G protein-coupled receptor 0.0
110 / 128     
Adenylate cyclase type V ADCY5 O95622 CHEMBL3189 Enzyme 0.0
2 / 0     
Tyrosine-protein kinase receptor UFO AXL P30530 CHEMBL4895 Kinase 0.0
3 / 0     
Tyrosine-protein kinase receptor TYRO3 TYRO3 Q06418 CHEMBL5314 Kinase 0.0
3 / 0     
Proto-oncogene tyrosine-protein kinase MER MERTK Q12866 CHEMBL5331 Kinase 0.0
3 / 0     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.0
123 / 31     
Melatonin receptor 1A MTNR1A P48039 CHEMBL1945 Family A G protein-coupled receptor 0.0
3 / 86     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.