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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Glutamate NMDA receptor; GRIN1/GRIN2B GRIN1 GRIN2B Q05586 Q13224 CHEMBL1907603 Ligand-gated ion channel 0.677770377193
1 / 9     
Glutamate NMDA receptor; GRIN1/GRIN2A GRIN2A GRIN1 Q12879 Q05586 CHEMBL1907604 Ligand-gated ion channel 0.677770377193
1 / 14     
Butyrylcholinesterase (by homology) BCHE P06276 CHEMBL1914 Hydrolase 0.677770377193
9 / 72     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.677770377193
14 / 42     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.677770377193
236 / 879     
Serotonin transporter (by homology) SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.42597438872
212 / 1136     
Dopamine transporter (by homology) SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.42597438872
238 / 1272     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.284705359937
17 / 953     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.221938203373
147 / 622     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.174862804543
66 / 192     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.174862804543
15 / 570     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.151315356696
7 / 295     
Nociceptin receptor OPRL1 P41146 CHEMBL2014 Family A G protein-coupled receptor 0.151315356696
0 / 336     
Synaptic vesicular amine transporter (by homology) SLC18A2 Q05940 CHEMBL1893 Electrochemical transporter 0.143473412261
26 / 173     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.143473412261
23 / 119     
Delta opioid receptor OPRD1 P41143 CHEMBL236 Family A G protein-coupled receptor 0.135616202575
10 / 603     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.135616202575
18 / 46     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.135616202575
19 / 37     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.135616202575
27 / 173     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.135616202575
30 / 267     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.127750341333
5 / 14     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.127750341333
150 / 567     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.119895126898
6 / 16     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.119895126898
14 / 15     
C-C chemokine receptor type 3 CCR3 P51677 CHEMBL3473 Family A G protein-coupled receptor 0.119895126898
2 / 71     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.119895126898
32 / 219     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.112041901328
22 / 33     
Voltage-gated T-type calcium channel alpha-1G subunit CACNA1G O43497 CHEMBL4641 Voltage-gated ion channel 0.112041901328
0 / 27     
Glutamate [NMDA] receptor subunit epsilon 2 GRIN2B Q13224 CHEMBL1904 Ligand-gated ion channel 0.112041901328
4 / 15     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.112041901328
22 / 133     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.112041901328
25 / 47     
Glycine transporter 1 SLC6A9 P48067 CHEMBL2337 Electrochemical transporter 0.112041901328
0 / 51     
C-X-C chemokine receptor type 3 CXCR3 P49682 CHEMBL4441 Family A G protein-coupled receptor 0.112041901328
14 / 85     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.112041901328
14 / 108     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.112041901328
22 / 133     
Sphingosine kinase 2 SPHK2 Q9NRA0 CHEMBL3023 Enzyme 0.112041901328
0 / 16     
Lanosterol synthase LSS P48449 CHEMBL3593 Enzyme 0.112041901328
0 / 8     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.112041901328
77 / 229     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.112041901328
18 / 40     
Cathepsin S CTSS P25774 CHEMBL2954 Protease 0.112041901328
0 / 16     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.112041901328
0 / 132     
11-beta-hydroxysteroid dehydrogenase 1 HSD11B1 P28845 CHEMBL4235 Enzyme 0.112041901328
0 / 252     
Voltage-gated potassium channel subunit Kv1.5 KCNA5 P22460 CHEMBL4306 Voltage-gated ion channel 0.112041901328
0 / 4     
Lethal(3)malignant brain tumor-like protein 3 L3MBTL3 Q96JM7 CHEMBL1287623 Reader 0.112041901328
0 / 52     
Nuclear receptor subfamily 1 group D member 2 NR1D2 Q14995 CHEMBL1961784 Nuclear receptor 0.112041901328
0 / 1     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.112041901328
16 / 13     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.112041901328
16 / 42     
MAP kinase p38 alpha MAPK14 Q16539 CHEMBL260 Kinase 0.112041901328
0 / 6     
Sphingosine 1-phosphate receptor Edg-5 S1PR2 O95136 CHEMBL2955 Family A G protein-coupled receptor 0.112041901328
0 / 16     
Cytochrome P450 2C9 CYP2C9 P11712 CHEMBL3397 Cytochrome P450 0.112041901328
0 / 5     
Sphingosine 1-phosphate receptor Edg-3 S1PR3 Q99500 CHEMBL3892 Family A G protein-coupled receptor 0.112041901328
0 / 21     
Sphingosine 1-phosphate receptor Edg-1 S1PR1 P21453 CHEMBL4333 Family A G protein-coupled receptor 0.112041901328
0 / 24     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.112041901328
17 / 23     
C-C chemokine receptor type 5 CCR5 P51681 CHEMBL274 Family A G protein-coupled receptor 0.112041901328
0 / 154     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.112041901328
9 / 11     
Neurokinin 1 receptor TACR1 P25103 CHEMBL249 Family A G protein-coupled receptor 0.112041901328
5 / 332     
Squalene synthetase (by homology) FDFT1 P37268 CHEMBL3338 Enzyme 0.112041901328
0 / 15     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.112041901328
12 / 38     
Arachidonate 5-lipoxygenase ALOX5 P09917 CHEMBL215 Oxidoreductase 0.112041901328
0 / 9     
Sphingosine 1-phosphate receptor Edg-6 S1PR4 O95977 CHEMBL3230 Family A G protein-coupled receptor 0.112041901328
0 / 15     
GABA transporter 2 (by homology) SLC6A13 Q9NSD5 CHEMBL4535 Electrochemical transporter 0.112041901328
0 / 3     
Melanocortin receptor 4 MC4R P32245 CHEMBL259 Family A G protein-coupled receptor 0.112041901328
0 / 112     
Gamma-secretase PSEN2 PSENEN NCSTN APH1A PSEN1 APH1B P49810 Q9NZ42 Q92542 Q96BI3 P49768 Q8WW43 CHEMBL2094135 Protease 0.112041901328
0 / 15     
Anti-estrogen binding site (AEBS) EBP Q15125 CHEMBL4931 Enzyme 0.0
1 / 15     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.0
7 / 20     
Vesicular acetylcholine transporter SLC18A3 Q16572 CHEMBL4767 Electrochemical transporter 0.0
1 / 97     
Dipeptidyl peptidase I CTSC P53634 CHEMBL2252 Protease 0.0
0 / 3     
Cathepsin K CTSK P43235 CHEMBL268 Protease 0.0
0 / 27     
Cathepsin L CTSL P07711 CHEMBL3837 Protease 0.0
0 / 17     
Cathepsin (B and K) CTSB P07858 CHEMBL4072 Protease 0.0
0 / 13     
Protein arginine N-methyltransferase 6 PRMT6 Q96LA8 CHEMBL1275221 Writer 0.0
0 / 1     
Protein arginine N-methyltransferase 8 PRMT8 Q9NR22 CHEMBL3108648 Writer 0.0
0 / 1     
Histone-arginine methyltransferase CARM1 CARM1 Q86X55 CHEMBL5406 Writer 0.0
0 / 1     
Malonyl-CoA decarboxylase MLYCD O95822 CHEMBL4698 Enzyme 0.0
0 / 25     
Lysine-specific histone demethylase 1 KDM1A O60341 CHEMBL6136 Eraser 0.0
2 / 62     
Epoxide hydratase EPHX2 P34913 CHEMBL2409 Protease 0.0
0 / 69     
Cytochrome P450 2C19 CYP2C19 P33261 CHEMBL3622 Cytochrome P450 0.0
2 / 6     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.0
0 / 27     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0
37 / 51     
Carbonic anhydrase II CA2 P00918 CHEMBL205 Lyase 0.0
0 / 13     
Carbonic anhydrase XII CA12 O43570 CHEMBL3242 Lyase 0.0
0 / 9     
Carbonic anhydrase IX CA9 Q16790 CHEMBL3594 Lyase 0.0
0 / 8     
P2X purinoceptor 7 P2RX7 Q99572 CHEMBL4805 Ligand-gated ion channel 0.0
1 / 21     
Sphingosine 1-phosphate receptor Edg-8 S1PR5 Q9H228 CHEMBL2274 Family A G protein-coupled receptor 0.0
0 / 17     
Neuropeptide Y receptor type 1 NPY1R P25929 CHEMBL4777 Family A G protein-coupled receptor 0.0
0 / 33     
N-acylsphingosine-amidohydrolase NAAA Q02083 CHEMBL4349 Enzyme 0.0
0 / 3     
Histone deacetylase 6 HDAC6 Q9UBN7 CHEMBL1865 Eraser 0.0
0 / 41     
MBT domain-containing protein 1 MBTD1 Q05BQ5 CHEMBL1287625 Reader 0.0
0 / 12     
Sphingosine kinase 1 SPHK1 Q9NYA1 CHEMBL4394 Enzyme 0.0
0 / 16     
Thyroid hormone receptor beta-1 THRB P10828 CHEMBL1947 Nuclear receptor 0.0
0 / 9     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.0
3 / 0     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.0
0 / 3     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.0
15 / 19     
Vasopressin V1a receptor AVPR1A P37288 CHEMBL1889 Family A G protein-coupled receptor 0.0
0 / 14     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.0
2 / 3     
Epoxide hydrolase 1 EPHX1 P07099 CHEMBL1968 Protease 0.0
0 / 21     
Glycine receptor subunit alpha-1 GLRA1 P23415 CHEMBL5845 Ligand-gated ion channel 0.0
0 / 1     
Steroid 5-alpha-reductase 1 SRD5A1 P18405 CHEMBL1787 Oxidoreductase 0.0
0 / 28     
C-C chemokine receptor type 1 CCR1 P32246 CHEMBL2413 Family A G protein-coupled receptor 0.0
0 / 66     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.0
20 / 29     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.