Target	Common name	Uniprot ID	ChEMBL ID	Target Class	Probability*	Known actives (3D/2D)
Xanthine dehydrogenase/oxidase	XDH	P47989	CHEMBL1929	Oxidoreductase	0.9937520024621282	160 / 34
Interleukin-2	IL2	P60568	CHEMBL5880	Secreted protein	0.9762706530963356	22 / 5
Tumor necrosis factor	TNF	P01375	CHEMBL1825	Secreted protein	0.9762706530963356	26 / 3
Aldo-keto reductase family 1 member B1	AKR1B1	P15121	CHEMBL1900	Oxidoreductase	0.9111020500728729	132 / 24
Inhibitor of nuclear factor kappa-B kinase subunit beta	IKBKB	O14920	CHEMBL1991	Kinase	0.9064851596386659	68 / 2
Matrix metalloproteinase-9	MMP9	P14780	CHEMBL321	Protease	0.88588797668749	109 / 5
Carbonic anhydrase 7	CA7	P43166	CHEMBL2326	Lyase	0.8673604972335495	101 / 23
Carbonic anhydrase 4	CA4	P22748	CHEMBL3729	Lyase	0.8673604972335495	68 / 16
Pyruvate kinase PKM	PKM	P14618	CHEMBL1075189	Enzyme	0.8673604972335495	19 / 10
Protein disulfide-isomerase	P4HB	P07237	CHEMBL5422	Isomerase	0.8673604972335495	81 / 2
Carbonic anhydrase 2	CA2	P00918	CHEMBL205	Lyase	0.8673604972335495	472 / 25
Lysine-specific histone demethylase 1A	KDM1A	O60341	CHEMBL6136	Eraser	0.8673604972335495	180 / 9
Carbonic anhydrase 12	CA12	O43570	CHEMBL3242	Lyase	0.8673604972335495	360 / 64
2-5A-dependent ribonuclease	RNASEL	Q05823	CHEMBL3575	Hydrolase	0.864541122959136	3 / 1
NADPH oxidase 4	NOX4	Q9NPH5	CHEMBL1250375	Oxidoreductase	0.8504529620738038	36 / 8
Alpha-2C adrenergic receptor	ADRA2C	P18825	CHEMBL1916	Family A G protein-coupled receptor	0.8504529620738038	21 / 2
Nicotinamide phosphoribosyltransferase	NAMPT	P43490	CHEMBL1744525	Enzyme	0.7777113326070487	6 / 1
Acetylcholinesterase	ACHE	P22303	CHEMBL220	Hydrolase	0.7554392044132267	186 / 185
Neuromedin-U receptor 2	NMUR2	Q9GZQ4	CHEMBL1075144	Family A G protein-coupled receptor	0.7251109316110401	2 / 1
Beta-secretase 1	BACE1	P56817	CHEMBL4822	Protease	0.7251109316110401	148 / 35
Amine oxidase [flavin-containing] A	MAOA	P21397	CHEMBL1951	Oxidoreductase	0.7251109316110401	213 / 62
Alpha-2A adrenergic receptor	ADRA2A	P08913	CHEMBL1867	Family A G protein-coupled receptor	0.7251109316110401	43 / 1
Synaptojanin-2	SYNJ2	O15056	CHEMBL4523129	Hydrolase	0.7125764254248651	16 / 6
Ribosomal protein S6 kinase alpha-3	RPS6KA3	P51812	CHEMBL2345	Kinase	0.6825879178326415	47 / 26
Ribosyldihydronicotinamide dehydrogenase [quinone]	NQO2	P16083	CHEMBL3959	Oxidoreductase	0.6740477787448858	21 / 1
Prostaglandin G/H synthase 2	PTGS2	P35354	CHEMBL230	Oxidoreductase	0.5874050566268901	144 / 83
Ribosomal protein S6 kinase alpha-1	RPS6KA1	Q15418	CHEMBL2553	Kinase	0.5440548540562957	13 / 3
Serine/threonine-protein kinase PLK1	PLK1	P53350	CHEMBL3024	Kinase	0.49950427718253604	33 / 6
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	CD38	P28907	CHEMBL4660	Enzyme	0.41904262730288255	4 / 3
Dipeptidyl peptidase 4	DPP4	P27487	CHEMBL284	Protease	0.41904262730288255	55 / 9
Polyunsaturated fatty acid 5-lipoxygenase	ALOX5	P09917	CHEMBL215	Oxidoreductase	0.35915119009066593	299 / 64
Beta-glucuronidase	GUSB	P08236	CHEMBL2728	Hydrolase	0.24219377744573292	53 / 4
Cystathionine beta-synthase	CBS	P35520	CHEMBL3399911	Enzyme	0.17340251370973075	9 / 4
Amyloid-beta precursor protein	APP	P05067	CHEMBL2487	Membrane receptor	0.14882977525526864	200 / 35
Sclerostin	SOST	Q9BQB4	CHEMBL3580487	Unclassified protein	0.13509511208084504	5 / 1
Epidermal growth factor receptor	EGFR	P00533	CHEMBL203	Kinase	0.12924295048728385	326 / 34
cGMP-specific 3',5'-cyclic phosphodiesterase	PDE5A	O76074	CHEMBL1827	Phosphodiesterase	0.12065485483668141	79 / 17
Ribosomal protein S6 kinase alpha-6	RPS6KA6	Q9UK32	CHEMBL4924	Kinase	0.12057958413709917	7 / 2
Multidrug resistance-associated protein 1	ABCC1	P33527	CHEMBL3004	Primary active transporter	0.1165063030116088	14 / 81
beta-catenin-B-cell lymphoma 9 protein complex	N/A	P35222&O00512	CHEMBL3885525	Unclassified protein	0.10171795719525027	11 / 19
Inositol hexakisphosphate kinase 2	IP6K2	Q9UHH9	CHEMBL4523488	Transferase	0.0860240100677728	9 / 10
Peroxisome proliferator-activated receptor gamma	PPARG	P37231	CHEMBL235	Nuclear receptor	0.08479461805475759	128 / 25
Aldehyde dehydrogenase, mitochondrial	ALDH2	P05091	CHEMBL1935	Oxidoreductase	0.08411956305442621	29 / 40
Carbonic anhydrase 1	CA1	P00915	CHEMBL261	Lyase	0.07790396202156208	407 / 22
ELAV-like protein 3	ELAVL3	Q14576	CHEMBL4105924	Unclassified protein	0.07781021972680306	5 / 3
MAP kinase-interacting serine/threonine-protein kinase 2	MKNK2	Q9HBH9	CHEMBL4204	Kinase	0.07482449914167122	34 / 7
G-protein coupled receptor 35	GPR35	Q9HC97	CHEMBL1293267	Family A G protein-coupled receptor	0.07337216926703505	29 / 5
Solute carrier organic anion transporter family member 2B1	SLCO2B1	O94956	CHEMBL1743124	Electrochemical transporter	0.07093328414263235	7 / 7
Plasminogen	PLG	P00747	CHEMBL1801	Protease	0.06691187674710228	66 / 4
Polyunsaturated fatty acid lipoxygenase ALOX15	ALOX15	P16050	CHEMBL2903	Oxidoreductase	0.060513690509274666	80 / 13
Collagenase 3	MMP13	P45452	CHEMBL280	Protease	0.059147469939755976	42 / 2
72 kDa type IV collagenase	MMP2	P08253	CHEMBL333	Protease	0.059147469939755976	159 / 3
Proto-oncogene tyrosine-protein kinase Src	SRC	P12931	CHEMBL267	Kinase	0.058475248009296536	282 / 11
Carbonic anhydrase 9	CA9	Q16790	CHEMBL3594	Lyase	0.05770353428479691	420 / 51
Broad substrate specificity ATP-binding cassette transporter ABCG2	ABCG2	Q9UNQ0	CHEMBL5393	Primary active transporter	0.05716732826349602	56 / 163
Alpha-synuclein	SNCA	P37840	CHEMBL6152	Unclassified protein	0.05715224977563597	77 / 5
D(4) dopamine receptor	DRD4	P21917	CHEMBL219	Family A G protein-coupled receptor	0.05715224977563597	120 / 2
ATP-dependent translocase ABCB1	ABCB1	P08183	CHEMBL4302	Primary active transporter	0.05522038408601483	81 / 127
Serine/threonine-protein kinase pim-1	PIM1	P11309	CHEMBL2147	Kinase	0.05459020456828601	157 / 11
Inositol polyphosphate multikinase	IPMK	Q8NFU5	CHEMBL4523401	Transferase	0.05392661619336228	5 / 6
Cytochrome P450 1B1	CYP1B1	Q16678	CHEMBL4878	Cytochrome P450	0.05392661619336228	46 / 129
Sphingosine kinase 1	SPHK1	Q9NYA1	CHEMBL4394	Enzyme	0.05304428298094588	7 / 1
Glycogen synthase kinase-3 beta	GSK3B	P49841	CHEMBL262	Kinase	0.05304428298094588	176 / 15
Hepatocyte growth factor receptor	MET	P08581	CHEMBL3717	Kinase	0.05094931221211781	220 / 4
Tyrosine-protein kinase SYK	SYK	P43405	CHEMBL2599	Kinase	0.050656497398193744	60 / 3
Stromelysin-1	MMP3	P08254	CHEMBL283	Protease	0.05036527613556263	39 / 2
Insulin-like growth factor 1 receptor	IGF1R	P08069	CHEMBL1957	Kinase	0.05036527613556263	41 / 3
Adenosine receptor A3	ADORA3	P0DMS8	CHEMBL256	Family A G protein-coupled receptor	0.04848916937177951	67 / 34
Glycogen phosphorylase, liver form	PYGL	P06737	CHEMBL2568	Transferase	0.04837070744594534	14 / 2
Receptor-type tyrosine-protein kinase FLT3	FLT3	P36888	CHEMBL1974	Kinase	0.04781474090500666	138 / 13
Vascular endothelial growth factor receptor 2	KDR	P35968	CHEMBL279	Kinase	0.04781474090500666	509 / 10
Pancreatic triacylglycerol lipase	PNLIP	P16233	CHEMBL1812	Hydrolase	0.04672096722007915	10 / 2
Telomerase reverse transcriptase	TERT	O14746	CHEMBL2916	Transferase	0.04467684313017081	45 / 31
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	PIK3CG	P48736	CHEMBL3267	Transferase	0.04358071988012047	120 / 1
RAC-alpha serine/threonine-protein kinase	AKT1	P31749	CHEMBL4282	Kinase	0.04358071988012047	66 / 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	PIK3CA	P42336	CHEMBL4005	Transferase	0.043328320284923866	193 / 1
DNA topoisomerase 2-alpha	TOP2A	P11388	CHEMBL1806	Isomerase	0.04307731663373169	23 / 7
Prothrombin	F2	P00734	CHEMBL204	Protease	0.041600221623778105	122 / 3
Lysine-specific demethylase 4E	KDM4E	B2RXH2	CHEMBL1293226	Eraser	0.041600221623778105	10 / 2
Histone deacetylase 6	HDAC6	Q9UBN7	CHEMBL1865	Eraser	0.041358796161030255	182 / 23
Insulin receptor	INSR	P06213	CHEMBL1981	Kinase	0.04087996145951126	22 / 1
C-X-C chemokine receptor type 1	CXCR1	P25024	CHEMBL4029	Family A G protein-coupled receptor	0.04040643683702026	188 / 1
Carbonic anhydrase 14	CA14	Q9ULX7	CHEMBL3510	Lyase	0.04017164907024682	87 / 2
Casein kinase II subunit alpha	CSNK2A1	P68400	CHEMBL3629	Kinase	0.039017190509202354	39 / 3
DNA repair nuclease/redox regulator APEX1	APEX1	P27695	CHEMBL5619	Enzyme	0.03879014885425963	14 / 2
Cyclin-dependent kinase 1	CDK1	P06493	CHEMBL308	Kinase	0.03879014885425963	118 / 13
17-beta-hydroxysteroid dehydrogenase type 2	HSD17B2	P37059	CHEMBL2789	Oxidoreductase	0.03811660688915992	226 / 5
Myeloperoxidase	MPO	P05164	CHEMBL2439	Oxidoreductase	0.03701892865330115	32 / 4
Aromatase	CYP19A1	P11511	CHEMBL1978	Cytochrome P450	0.036803069597898495	94 / 28
Short transient receptor potential channel 5	TRPC5	Q9UL62	CHEMBL1250411	Voltage-gated ion channel	0.03658842140281907	5 / 4
Catenin beta-1	CTNNB1	P35222	CHEMBL5866	Unclassified protein	0.03616273267562441	6 / 3
Aldehyde dehydrogenase X, mitochondrial	ALDH1B1	P30837	CHEMBL4881	Oxidoreductase	0.035832453342717695	1 / 1
Retinal dehydrogenase 2	ALDH1A2	O94788	CHEMBL3112384	Oxidoreductase	0.035832453342717695	1 / 1
Aurora kinase B	AURKB	Q96GD4	CHEMBL2185	Kinase	0.034710055881112575	90 / 4
Microtubule-associated protein tau	MAPT	P10636	CHEMBL1293224	Other cytosolic protein	0.034710055881112575	30 / 1
Maltase-glucoamylase	MGAM	O43451	CHEMBL2074	Hydrolase	0.03424761423449109	25 / 7
Lactoylglutathione lyase	GLO1	Q04760	CHEMBL2424	Lyase	0.03350982211231079	13 / 4
Carbonic anhydrase 3	CA3	P07451	CHEMBL2885	Lyase	0.033118720112260344	11 / 2
Carbonic anhydrase 5A, mitochondrial	CA5A	P35218	CHEMBL4789	Lyase	0.03292482577923157	34 / 4
Carbonic anhydrase 6	CA6	P23280	CHEMBL3025	Lyase	0.03292482577923157	32 / 1

*Probability for the query molecule - assumed as bioactive - to have this protein as target.