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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.298481092692
69 / 488     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.233887254578
57 / 479     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.161187413368
89 / 266     
Dopamine transporter (by homology) SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.145047351806
355 / 114     
Serotonin transporter (by homology) SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.128898633299
416 / 473     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.128898633299
359 / 486     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.120823671646
192 / 282     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.120823671646
90 / 290     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.120823671646
84 / 164     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.120823671646
338 / 109     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.112748418065
21 / 21     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.112748418065
30 / 50     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.112748418065
78 / 77     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.112748418065
144 / 152     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.112748418065
15 / 42     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.112748418065
247 / 127     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.104671941128
45 / 68     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.104671941128
20 / 16     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.104671941128
20 / 19     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.104671941128
46 / 22     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.104671941128
47 / 81     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.104671941128
7 / 18     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.104671941128
10 / 12     
Nociceptin receptor OPRL1 P41146 CHEMBL2014 Family A G protein-coupled receptor 0.104671941128
52 / 43     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.104671941128
78 / 243     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.104671941128
73 / 86     
Synaptic vesicular amine transporter (by homology) SLC18A2 Q05940 CHEMBL1893 Electrochemical transporter 0.104671941128
55 / 5     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.104671941128
32 / 40     
Transient receptor potential cation channel subfamily M member 8 (by homology) TRPM8 Q7Z2W7 CHEMBL1075319 Voltage-gated ion channel 0.104671941128
1 / 1     
Glutamate [NMDA] receptor subunit epsilon 2 GRIN2B Q13224 CHEMBL1904 Ligand-gated ion channel 0.104671941128
14 / 3     
Dopamine D5 receptor DRD5 P21918 CHEMBL1850 Family A G protein-coupled receptor 0.104671941128
19 / 24     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.104671941128
78 / 53     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.104671941128
13 / 14     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.104671941128
7 / 7     
Beta-3 adrenergic receptor ADRB3 P13945 CHEMBL246 Family A G protein-coupled receptor 0.104671941128
0 / 21     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.104671941128
76 / 45     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.104671941128
8 / 75     
Mas-related G-protein coupled receptor member X1 MRGPRX1 Q96LB2 CHEMBL5850 Unclassified protein 0.104671941128
2 / 0     
Cathepsin L CTSL P07711 CHEMBL3837 Protease 0.104671941128
0 / 30     
Melatonin receptor 1A MTNR1A P48039 CHEMBL1945 Family A G protein-coupled receptor 0.104671941128
0 / 125     
Melatonin receptor 1B MTNR1B P49286 CHEMBL1946 Family A G protein-coupled receptor 0.104671941128
0 / 115     
Tyrosine-protein kinase FYN FYN P06241 CHEMBL1841 Kinase 0.104671941128
3 / 0     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.104671941128
24 / 0     
Estrogen-related receptor alpha ESRRA P11474 CHEMBL3429 Nuclear receptor 0.104671941128
2 / 0     
Squalene monooxygenase SQLE Q14534 CHEMBL3592 Enzyme 0.104671941128
1 / 0     
Cytochrome P450 2C19 CYP2C19 P33261 CHEMBL3622 Cytochrome P450 0.104671941128
2 / 0     
Anandamide amidohydrolase FAAH O00519 CHEMBL2243 Enzyme 0.104671941128
0 / 2     
Delta opioid receptor OPRD1 P41143 CHEMBL236 Family A G protein-coupled receptor 0.104671941128
43 / 158     
Beta-1 adrenergic receptor ADRB1 P08588 CHEMBL213 Family A G protein-coupled receptor 0.104671941128
1 / 42     
Kinesin-like protein 1 KIF11 P52732 CHEMBL4581 Other cytosolic protein 0.104671941128
17 / 28     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.104671941128
10 / 108     
Macrophage colony stimulating factor receptor CSF1R P07333 CHEMBL1844 Kinase 0.104671941128
0 / 1     
Inhibitor of nuclear factor kappa B kinase beta subunit IKBKB O14920 CHEMBL1991 Kinase 0.104671941128
0 / 7     
Inhibitor of NF-kappa-B kinase (IKK) CHUK O15111 CHEMBL3476 Kinase 0.104671941128
0 / 5     
Tyrosine-protein kinase BTK BTK Q06187 CHEMBL5251 Kinase 0.104671941128
0 / 2     
Anti-estrogen binding site (AEBS) EBP Q15125 CHEMBL4931 Enzyme 0.104671941128
4 / 0     
Neurokinin 3 receptor TACR3 P29371 CHEMBL4429 Family A G protein-coupled receptor 0.104671941128
0 / 12     
Endothelin-converting enzyme 1 ECE1 P42892 CHEMBL4791 Protease 0.104671941128
0 / 57     
Toll-like receptor 8 TLR8 Q9NR97 CHEMBL5805 Toll-like and Il-1 receptors 0.104671941128
0 / 22     
GABA transporter 3 (by homology) SLC6A11 P48066 CHEMBL5208 Electrochemical transporter 0.104671941128
1 / 0     
Calcium sensing receptor CASR P41180 CHEMBL1878 Family C G protein-coupled receptor 0.104671941128
1 / 0     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.104671941128
12 / 191     
Cannabinoid receptor 2 CNR2 P34972 CHEMBL253 Family A G protein-coupled receptor 0.104671941128
5 / 159     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.104671941128
8 / 45     
Melanocortin receptor 1 MC1R Q01726 CHEMBL3795 Family A G protein-coupled receptor 0.104671941128
0 / 147     
Neurokinin 1 receptor TACR1 P25103 CHEMBL249 Family A G protein-coupled receptor 0.0
9 / 181     
Cathepsin (B and K) CTSB P07858 CHEMBL4072 Protease 0.0
0 / 22     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0
18 / 10     
Dipeptidyl peptidase I CTSC P53634 CHEMBL2252 Protease 0.0
0 / 7     
Melanocortin receptor 3 MC3R P41968 CHEMBL4644 Family A G protein-coupled receptor 0.0
0 / 91     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0
0 / 120     
Isoprenylcysteine carboxyl methyltransferase ICMT O60725 CHEMBL4699 Enzyme 0.0
19 / 44     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.0
8 / 0     
Voltage-gated potassium channel subunit Kv1.3 KCNA3 P22001 CHEMBL4633 Voltage-gated ion channel 0.0
5 / 0     
Melanocortin receptor 4 MC4R P32245 CHEMBL259 Family A G protein-coupled receptor 0.0
0 / 200     
DNA (cytosine-5)-methyltransferase 1 (by homology) DNMT1 P26358 CHEMBL1993 Writer 0.0
0 / 3     
Cytochrome P450 51 CYP51A1 Q16850 CHEMBL3849 Cytochrome P450 0.0
0 / 3     
G-protein coupled bile acid receptor 1 GPBAR1 Q8TDU6 CHEMBL5409 Family A G protein-coupled receptor 0.0
0 / 1     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0
67 / 3     
Gonadotropin-releasing hormone receptor GNRHR P30968 CHEMBL1855 Family A G protein-coupled receptor 0.0
0 / 97     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.0
0 / 12     
Serotonin 3a (5-HT3a) receptor HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0
24 / 13     
Intermediate conductance calcium-activated potassium channel protein 4 KCNN4 O15554 CHEMBL4305 Voltage-gated ion channel 0.0
3 / 0     
Vanilloid receptor TRPV1 Q8NER1 CHEMBL4794 Voltage-gated ion channel 0.0
1 / 15     
GABA-A receptor; alpha-3/beta-3/gamma-2 GABRB3 GABRA3 GABRG2 P28472 P34903 P18507 CHEMBL2094120 Ligand-gated ion channel 0.0
0 / 13     
GABA-A receptor; alpha-2/beta-3/gamma-2 GABRA2 GABRB3 GABRG2 P47869 P28472 P18507 CHEMBL2094130 Ligand-gated ion channel 0.0
0 / 13     
GABA-A receptor; alpha-1/beta-2/gamma-2 GABRA1 GABRB2 GABRG2 P14867 P47870 P18507 CHEMBL2095172 Ligand-gated ion channel 0.0
0 / 26     
Cytosolic phospholipase A2 PLA2G4A P47712 CHEMBL3816 Enzyme 0.0
0 / 31     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.0
2 / 14     
Cyclin-dependent kinase 4 CDK4 P11802 CHEMBL331 Kinase 0.0
0 / 3     
Proteasome Macropain subunit MB1 PSMB5 P28074 CHEMBL4662 Protease 0.0
0 / 9     
Cannabinoid receptor 1 CNR1 P21554 CHEMBL218 Family A G protein-coupled receptor 0.0
3 / 141     
Calpain 1 CAPN1 P07384 CHEMBL3891 Protease 0.0
0 / 7     
Ghrelin receptor GHSR Q92847 CHEMBL4616 Family A G protein-coupled receptor 0.0
0 / 47     
Histone deacetylase 1 HDAC1 Q13547 CHEMBL325 Eraser 0.0
0 / 82     
11-beta-hydroxysteroid dehydrogenase 1 HSD11B1 P28845 CHEMBL4235 Enzyme 0.0
2 / 39     
C-C chemokine receptor type 3 CCR3 P51677 CHEMBL3473 Family A G protein-coupled receptor 0.0
7 / 18     
Acetylcholine receptor; alpha1/beta1/delta/gamma CHRNB1 CHRNA1 CHRNG CHRND P11230 P02708 P07510 Q07001 CHEMBL1907588 Ligand-gated ion channel 0.0
0 / 3     
Neuronal acetylcholine receptor; alpha4/beta4 CHRNB4 CHRNA4 P30926 P43681 CHEMBL1907591 Ligand-gated ion channel 0.0
0 / 5     
Cyclin-dependent kinase 4/cyclin D1 CCND1 CDK4 P24385 P11802 CHEMBL1907601 Kinase 0.0
0 / 29     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.