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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Melatonin receptor 1A MTNR1A P48039 CHEMBL1945 Family A G protein-coupled receptor 1.0
620 / 329     
Melatonin receptor 1B MTNR1B P49286 CHEMBL1946 Family A G protein-coupled receptor 1.0
557 / 278     
Quinone reductase 2 NQO2 P16083 CHEMBL3959 Enzyme 1.0
79 / 24     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.382339714203
96 / 56     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.27410046585
253 / 186     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.247144676105
221 / 118     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.228987972479
172 / 209     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.184102382917
162 / 226     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.13892441008
82 / 51     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.130044232988
244 / 70     
Serotonin 5a (5-HT5a) receptor HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.120996592528
50 / 32     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.112023617719
15 / 258     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.112023617719
99 / 53     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.112023617719
10 / 22     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.103007427917
10 / 279     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.0940053518494
65 / 50     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.0940053518494
65 / 29     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.0940053518494
25 / 11     
Vanilloid receptor TRPV1 Q8NER1 CHEMBL4794 Voltage-gated ion channel 0.0940053518494
440 / 43     
Cyclooxygenase-2 PTGS2 P35354 CHEMBL230 Oxidoreductase 0.0849972473594
549 / 116     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0849972473594
63 / 220     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.0849972473594
27 / 13     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0849972473594
17 / 10     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.0849972473594
34 / 32     
Anandamide amidohydrolase FAAH O00519 CHEMBL2243 Enzyme 0.0849972473594
209 / 1     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0759736341678
17 / 11     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0669750160137
33 / 40     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0669750160137
7 / 7     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0669750160137
83 / 100     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.0669750160137
97 / 56     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.0579568757034
93 / 24     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0579568757034
278 / 1     
Vascular endothelial growth factor receptor 2 KDR P35968 CHEMBL279 Kinase 0.0579568757034
1026 / 82     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.0579568757034
879 / 28     
Leukotriene A4 hydrolase LTA4H P09960 CHEMBL4618 Protease 0.0579568757034
19 / 17     
Vascular endothelial growth factor receptor 3 FLT4 P35916 CHEMBL1955 Kinase 0.048952897826
61 / 29     
GABA receptor alpha-1 subunit (by homology) GABRA1 P14867 CHEMBL1962 Ligand-gated ion channel 0.048952897826
34 / 14     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.048952897826
1 / 13     
MAP kinase-activated protein kinase 2 MAPKAPK2 P49137 CHEMBL2208 Kinase 0.048952897826
141 / 39     
Phospholipase A2 group IIA PLA2G2A P14555 CHEMBL3474 Enzyme 0.048952897826
35 / 113     
Insulin-like growth factor I receptor IGF1R P08069 CHEMBL1957 Kinase 0.048952897826
190 / 26     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.048952897826
277 / 247     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.048952897826
505 / 61     
Androgen Receptor AR P10275 CHEMBL1871 Nuclear receptor 0.048952897826
248 / 3     
Phosphodiesterase 9A PDE9A O76083 CHEMBL3535 Phosphodiesterase 0.048952897826
33 / 0     
Ribosomal protein S6 kinase alpha 3 RPS6KA3 P51812 CHEMBL2345 Kinase 0.048952897826
118 / 0     
Cyclin-dependent kinase 4 CDK4 P11802 CHEMBL331 Kinase 0.048952897826
99 / 3     
Metabotropic glutamate receptor 5 (by homology) GRM5 P41594 CHEMBL3227 Family C G protein-coupled receptor 0.048952897826
698 / 0     
Interleukin-1 receptor-associated kinase 4 IRAK4 Q9NWZ3 CHEMBL3778 Kinase 0.048952897826
39 / 0     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.048952897826
21 / 41     
11-beta-hydroxysteroid dehydrogenase 1 HSD11B1 P28845 CHEMBL4235 Enzyme 0.048952897826
615 / 25     
Phosphodiesterase 4D PDE4D Q08499 CHEMBL288 Phosphodiesterase 0.048952897826
111 / 0     
Matrix metalloproteinase 9 MMP9 P14780 CHEMBL321 Protease 0.048952897826
171 / 53     
Glycogen synthase kinase-3 alpha GSK3A P49840 CHEMBL2850 Kinase 0.048952897826
82 / 0     
Metabotropic glutamate receptor 1 GRM1 Q13255 CHEMBL3772 Family C G protein-coupled receptor 0.048952897826
73 / 0     
Metabotropic glutamate receptor 4 GRM4 Q14833 CHEMBL2736 Family C G protein-coupled receptor 0.048952897826
98 / 0     
Dual specificity protein kinase TTK TTK P33981 CHEMBL3983 Kinase 0.048952897826
62 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.048952897826
166 / 0     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.048952897826
31 / 0     
Cyclin-dependent kinase 4/cyclin D1 CCND1 CDK4 P24385 P11802 CHEMBL1907601 Kinase 0.048952897826
125 / 22     
dUTP pyrophosphatase DUT P33316 CHEMBL5203 Enzyme 0.048952897826
39 / 0     
c-Jun N-terminal kinase 1 MAPK8 P45983 CHEMBL2276 Kinase 0.048952897826
356 / 0     
PI3-kinase p110-beta subunit PIK3CB P42338 CHEMBL3145 Enzyme 0.048952897826
217 / 0     
PI3-kinase p110-gamma subunit PIK3CG P48736 CHEMBL3267 Enzyme 0.048952897826
274 / 0     
PI3-kinase p110-alpha subunit PIK3CA P42336 CHEMBL4005 Enzyme 0.048952897826
613 / 0     
Mineralocorticoid receptor NR3C2 P08235 CHEMBL1994 Nuclear receptor 0.048952897826
157 / 6     
Glucocorticoid receptor NR3C1 P04150 CHEMBL2034 Nuclear receptor 0.048952897826
329 / 12     
Potassium channel subfamily K member 3 KCNK3 O14649 CHEMBL2321613 Voltage-gated ion channel 0.048952897826
44 / 0     
Potassium channel subfamily K member 9 KCNK9 Q9NPC2 CHEMBL2321614 Voltage-gated ion channel 0.048952897826
32 / 0     
CDK8/Cyclin C CCNC CDK8 P24863 P49336 CHEMBL3038474 Kinase 0.048952897826
45 / 0     
Cell division protein kinase 8 CDK8 P49336 CHEMBL5719 Kinase 0.048952897826
46 / 0     
Pyruvate kinase isozymes M1/M2 PKM P14618 CHEMBL1075189 Enzyme 0.048952897826
32 / 0     
Tyrosine-protein kinase ITK/TSK ITK Q08881 CHEMBL2959 Kinase 0.048952897826
100 / 0     
Histone acetyltransferase PCAF KAT2B Q92831 CHEMBL5500 Writer 0.048952897826
14 / 0     
Progesterone receptor PGR P06401 CHEMBL208 Nuclear receptor 0.048952897826
347 / 5     
Receptor protein-tyrosine kinase erbB-2 ERBB2 P04626 CHEMBL1824 Kinase 0.048952897826
164 / 0     
Protein kinase N2 PKN2 Q16513 CHEMBL3032 Kinase 0.048952897826
3 / 0     
Tyrosine-protein kinase BRK PTK6 Q13882 CHEMBL4601 Kinase 0.048952897826
22 / 0     
Adenosine A2b receptor ADORA2B P29275 CHEMBL255 Family A G protein-coupled receptor 0.048952897826
139 / 0     
Transient receptor potential cation channel subfamily A member 1 TRPA1 O75762 CHEMBL6007 Voltage-gated ion channel 0.048952897826
37 / 0     
Bromodomain-containing protein 4 BRD4 O60885 CHEMBL1163125 Reader 0.048952897826
267 / 0     
c-Jun N-terminal kinase 3 MAPK10 P53779 CHEMBL2637 Kinase 0.048952897826
236 / 0     
Beta secretase 2 BACE2 Q9Y5Z0 CHEMBL2525 Protease 0.048952897826
142 / 0     
Steryl-sulfatase STS P08842 CHEMBL3559 Enzyme 0.048952897826
71 / 0     
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Q5S007 CHEMBL1075104 Kinase 0.048952897826
139 / 0     
MAP kinase signal-integrating kinase 2 MKNK2 Q9HBH9 CHEMBL4204 Kinase 0.048952897826
33 / 0     
G protein-coupled receptor kinase 6 GRK6 P43250 CHEMBL6144 Kinase 0.048952897826
5 / 0     
CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase) DBF4 CDC7 Q9UBU7 O00311 CHEMBL2111377 Kinase 0.048952897826
61 / 0     
Dual specificity protein phosphatase 3 DUSP3 P51452 CHEMBL2635 Phosphatase 0.048952897826
17 / 0     
Bromodomain adjacent to zinc finger domain protein 2B BAZ2B Q9UIF8 CHEMBL1741220 Reader 0.048952897826
9 / 0     
Serine/threonine-protein kinase mTOR (by homology) MTOR P42345 CHEMBL2842 Kinase 0.048952897826
379 / 0     
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Q9UIF9 CHEMBL3108642 Reader 0.048952897826
7 / 0     
Probable protein-cysteine N-palmitoyltransferase porcupine PORCN Q9H237 CHEMBL1255163 Enzyme 0.048952897826
23 / 0     
Polyadenylate-binding protein 1 PABPC1 P11940 CHEMBL1293286 Unclassified protein 0.048952897826
18 / 0     
Thymidylate synthase TYMS P04818 CHEMBL1952 Transferase 0.048952897826
64 / 0     
Cyclin-dependent kinase 4/cyclin D CCND3 CCND1 CDK4 CCND2 P30281 P24385 P11802 P30279 CHEMBL2095942 Other cytosolic protein 0.048952897826
35 / 0     
Muscle glycogen synthase GYS1 P13807 CHEMBL4000 Enzyme 0.048952897826
2 / 0     
p53-binding protein Mdm-2 MDM2 Q00987 CHEMBL5023 Other nuclear protein 0.048952897826
122 / 0     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.048952897826
69 / 51     
Long-chain fatty acid transport protein 1 SLC27A1 Q6PCB7 CHEMBL2052038 Electrochemical transporter 0.048952897826
18 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.