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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 1.0
65 / 6     
Indoleamine 2,3-dioxygenase IDO1 P14902 CHEMBL4685 Enzyme 1.0
12 / 12     
Dual specificity phosphatase Cdc25B CDC25B P30305 CHEMBL4804 Phosphatase 1.0
11 / 11     
Monoamine oxidase A MAOA P21397 CHEMBL1951 Oxidoreductase 0.124537699969
24 / 2     
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Q02750 CHEMBL3587 Kinase 0.124537699969
3 / 1     
Dual specificity protein phosphatase 1 (by homology) DUSP1 P28562 CHEMBL6026 Enzyme 0.124537699969
2 / 2     
Histone acetyltransferase p300 EP300 Q09472 CHEMBL3784 Writer 0.080569968052
0 / 1     
Serine/threonine-protein kinase PLK1 PLK1 P53350 CHEMBL3024 Kinase 0.0717871625222
1 / 0     
Monoglyceride lipase MGLL Q99685 CHEMBL4191 Enzyme 0.0717871625222
20 / 0     
Glycogen synthase kinase-3 beta GSK3B P49841 CHEMBL262 Kinase 0.0717871625222
21 / 0     
DNA-(apurinic or apyrimidinic site) lyase APEX1 P27695 CHEMBL5619 Enzyme 0.0717871625222
0 / 11     
Cytochrome P450 11B1 CYP11B1 P15538 CHEMBL1908 Cytochrome P450 0.0717871625222
6 / 0     
Cytochrome P450 11B2 CYP11B2 P19099 CHEMBL2722 Cytochrome P450 0.0717871625222
5 / 0     
Aryl hydrocarbon receptor AHR P35869 CHEMBL3201 Transcription factor 0.0717871625222
23 / 0     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0717871625222
39 / 0     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0
0 / 3     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.0
5 / 0     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.0
5 / 0     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.0
5 / 0     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0
11 / 0     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0
22 / 0     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0
5 / 0     
Neuronal acetylcholine receptor protein alpha-7 subunit CHRNA7 P36544 CHEMBL2492 Ligand-gated ion channel 0.0
1 / 0     
Glutathione reductase GSR P00390 CHEMBL2755 Oxidoreductase 0.0
2 / 4     
Beta-secretase 1 BACE1 P56817 CHEMBL4822 Protease 0.0
1 / 3     
DNA (cytosine-5)-methyltransferase 1 DNMT1 P26358 CHEMBL1993 Writer 0.0
1 / 1     
DNMT3A2/3L complex DNMT3L DNMT3A Q9UJW3 Q9Y6K1 CHEMBL3137291 Reader 0.0
1 / 1     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.0
19 / 0     
Cytochrome P450 2A6 CYP2A6 P11509 CHEMBL5282 Cytochrome P450 0.0
11 / 0     
Hematopoietic prostaglandin D synthase HPGDS O60760 CHEMBL5879 Transferase 0.0
1 / 0     
Thyroid hormone receptor beta-1 THRB P10828 CHEMBL1947 Nuclear receptor 0.0
0 / 2     
G-protein coupled receptor 35 GPR35 Q9HC97 CHEMBL1293267 Family A G protein-coupled receptor 0.0
0 / 1     
Transient receptor potential cation channel subfamily A member 1 TRPA1 O75762 CHEMBL6007 Voltage-gated ion channel 0.0
3 / 0     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.0
17 / 9     
Nitric oxide synthase, inducible (by homology) NOS2 P35228 CHEMBL4481 Enzyme 0.0
14 / 0     
Histone deacetylase 8 HDAC8 Q9BY41 CHEMBL3192 Eraser 0.0
1 / 0     
Acyl coenzyme A:cholesterol acyltransferase 1 SOAT1 P35610 CHEMBL2782 Enzyme 0.0
2 / 13     
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 MALT1 Q9UDY8 CHEMBL3632452 Hydrolase 0.0
6 / 0     
Matrix metalloproteinase 2 MMP2 P08253 CHEMBL333 Protease 0.0
1 / 0     
Alcohol dehydrogenase alpha chain ADH1A P07327 CHEMBL1970 Oxidoreductase 0.0
13 / 0     
Poly [ADP-ribose] polymerase 3 PARP3 Q9Y6F1 CHEMBL5083 Enzyme 0.0
1 / 0     
Angiotensin-converting enzyme (by homology) ACE P12821 CHEMBL1808 Protease 0.0
1 / 0     
Lysine-specific demethylase 4D-like KDM4E B2RXH2 CHEMBL1293226 Eraser 0.0
1 / 0     
Tyrosyl-DNA phosphodiesterase 2 TDP2 O95551 CHEMBL2169736 Enzyme 0.0
3 / 0     
Mannose-6-phosphate isomerase MPI P34949 CHEMBL2758 Isomerase 0.0
0 / 1     
Signal transducer and activator of transcription 3 STAT3 P40763 CHEMBL4026 Transcription factor 0.0
0 / 1     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.0
9 / 0     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0
6 / 0     
Cathepsin S CTSS P25774 CHEMBL2954 Protease 0.0
4 / 0     
Nitric-oxide synthase, brain NOS1 P29475 CHEMBL3568 Enzyme 0.0
1 / 0     
Cathepsin (B and K) CTSB P07858 CHEMBL4072 Protease 0.0
5 / 0     
11-beta-hydroxysteroid dehydrogenase 1 HSD11B1 P28845 CHEMBL4235 Enzyme 0.0
18 / 0     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.0
1 / 0     
Telomerase reverse transcriptase TERT O14746 CHEMBL2916 Enzyme 0.0
4 / 0     
Histone acetyltransferase PCAF KAT2B Q92831 CHEMBL5500 Writer 0.0
6 / 0     
Caspase-3 CASP3 P42574 CHEMBL2334 Protease 0.0
3 / 0     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0
2 / 0     
Lysine-specific demethylase 4C KDM4C Q9H3R0 CHEMBL6175 Eraser 0.0
6 / 0     
Phosphodiesterase 7A PDE7A Q13946 CHEMBL3012 Phosphodiesterase 0.0
7 / 0     
Alcohol dehydrogenase beta chain ADH1B P00325 CHEMBL3284 Oxidoreductase 0.0
7 / 0     
Alcohol dehydrogenase gamma chain ADH1C P00326 CHEMBL3285 Oxidoreductase 0.0
4 / 0     
Carbonic anhydrase VII CA7 P43166 CHEMBL2326 Lyase 0.0
6 / 0     
Carbonic anhydrase XIV CA14 Q9ULX7 CHEMBL3510 Lyase 0.0
8 / 0     
Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 P12268 CHEMBL2002 Oxidoreductase 0.0
1 / 0     
GABA-A receptor; alpha-5/beta-3/gamma-2 GABRB3 GABRG2 GABRA5 P28472 P18507 P31644 CHEMBL2094122 Ligand-gated ion channel 0.0
7 / 0     
c-Jun N-terminal kinase 1 MAPK8 P45983 CHEMBL2276 Kinase 0.0
12 / 0     
Regulator of G-protein signaling 4 RGS4 P49798 CHEMBL1795091 Unclassified protein 0.0
1 / 0     
Thrombin F2 P00734 CHEMBL204 Protease 0.0
4 / 0     
Adenosine A1 receptor ADORA1 P30542 CHEMBL226 Family A G protein-coupled receptor 0.0
3 / 0     
Chymotrypsin C CTRC Q99895 CHEMBL2386 Protease 0.0
1 / 0     
Leukocyte elastase ELANE P08246 CHEMBL248 Protease 0.0
4 / 0     
Adenosine A2a receptor ADORA2A P29274 CHEMBL251 Family A G protein-coupled receptor 0.0
4 / 0     
Cathepsin G CTSG P08311 CHEMBL4071 Protease 0.0
1 / 0     
Phosphodiesterase 4B PDE4B Q07343 CHEMBL275 Phosphodiesterase 0.0
1 / 0     
Phosphodiesterase 4D PDE4D Q08499 CHEMBL288 Phosphodiesterase 0.0
1 / 0     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.0
1 / 0     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0
1 / 0     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0
1 / 0     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.0
1 / 0     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.0
1 / 0     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.0
1 / 0     
Thymidine phosphorylase TYMP P19971 CHEMBL3106 Enzyme 0.0
6 / 0     
MAP kinase ERK2 MAPK1 P28482 CHEMBL4040 Kinase 0.0
1 / 0     
N-acylsphingosine-amidohydrolase (by homology) NAAA Q02083 CHEMBL4349 Enzyme 0.0
9 / 0     
Thyroid peroxidase TPO P07202 CHEMBL1839 Oxidoreductase 0.0
1 / 0     
Dipeptidyl peptidase I CTSC P53634 CHEMBL2252 Protease 0.0
2 / 0     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.0
3 / 0     
Carbonic anhydrase VB CA5B Q9Y2D0 CHEMBL3969 Lyase 0.0
3 / 0     
Carbonic anhydrase XIII (by homology) CA13 Q8N1Q1 CHEMBL3912 Lyase 0.0
4 / 0     
Tyrosine-protein kinase SYK SYK P43405 CHEMBL2599 Kinase 0.0
2 / 0     
Hormone sensitive lipase LIPE Q05469 CHEMBL3590 Enzyme 0.0
1 / 0     
Cathepsin L CTSL P07711 CHEMBL3837 Protease 0.0
5 / 0     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0
3 / 0     
Protein-glutamine gamma-glutamyltransferase TGM2 P21980 CHEMBL2730 Enzyme 0.0
7 / 0     
Metabotropic glutamate receptor 5 (by homology) GRM5 P41594 CHEMBL3227 Family C G protein-coupled receptor 0.0
12 / 0     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.0
1 / 0     
Macrophage migration inhibitory factor MIF P14174 CHEMBL2085 Enzyme 0.0
2 / 0     
Trypsin I PRSS1 P07477 CHEMBL209 Protease 0.0
2 / 0     
Heme oxygenase 1 (by homology) HMOX1 P09601 CHEMBL2823 Enzyme 0.0
6 / 0     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.0
1 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.