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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Neuronal acetylcholine receptor protein alpha-7 subunit CHRNA7 P36544 CHEMBL2492 Ligand-gated ion channel 0.147106563998
 207 / 14     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.112450964818
 1629 / 495     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.103761755413
 949 / 59     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.103761755413
 1785 / 319     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.0864426933852
 26 / 11     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.0690974435253
 254 / 12     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.0690974435253
 138 / 25     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0690974435253
 324 / 62     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0690974435253
 468 / 149     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0690974435253
 267 / 54     
Serotonin 3a (5-HT3a) receptor HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0690974435253
 157 / 8     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0690974435253
 365 / 44     
Serotonin 1b (5-HT1b) receptor (by homology) HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.0604245879294
 195 / 3     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0604245879294
 1135 / 77     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.0604245879294
 345 / 0     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0604245879294
 621 / 109     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0604245879294
 367 / 6     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.0604245879294
 333 / 21     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.0604245879294
 149 / 22     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.0604245879294
 423 / 12     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.0604245879294
 611 / 12     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.0604245879294
 159 / 5     
Acetylcholinesterase ACHE P22303 CHEMBL220 Hydrolase 0.0604245879294
 116 / 13     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.0604245879294
 372 / 44     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.0604245879294
 41 / 6     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0604245879294
 26 / 6     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.0604245879294
 266 / 37     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.0604245879294
 189 / 12     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0604245879294
 279 / 4     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0604245879294
 49 / 5     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0604245879294
 22 / 4     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.0604245879294
 149 / 3     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.0604245879294
 47 / 6     
Alpha-1a adrenergic receptor (by homology) ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.0604245879294
 124 / 7     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0604245879294
 61 / 3     
Calcium-activated potassium channel subunit alpha-1 KCNMA1 Q12791 CHEMBL4304 Voltage-gated ion channel 0.0604245879294
 1 / 0     
C-C motif chemokine 2 CCL2 P13500 CHEMBL1649052 Family A G protein-coupled receptor 0.0604245879294
 3 / 0     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.0604245879294
 120 / 0     
Rho-associated protein kinase ROCK2 ROCK1 O75116 Q13464 CHEMBL2111459 Kinase 0.0604245879294
 51 / 0     
Myosin light chain kinase, smooth muscle MYLK Q15746 CHEMBL2428 Kinase 0.0604245879294
 3 / 0     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.0604245879294
 128 / 0     
Protein kinase N2 PKN2 Q16513 CHEMBL3032 Kinase 0.0604245879294
 7 / 0     
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Q9UIF9 CHEMBL3108642 Reader 0.0604245879294
 8 / 0     
Rho-associated protein kinase 1 ROCK1 Q13464 CHEMBL3231 Kinase 0.0604245879294
 45 / 0     
Protein kinase N1 PKN1 Q16512 CHEMBL3384 Kinase 0.0604245879294
 5 / 0     
Ribosomal protein S6 kinase alpha 5 RPS6KA5 O75582 CHEMBL4237 Kinase 0.0604245879294
 4 / 0     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.0604245879294
 123 / 4     
Neuronal acetylcholine receptor; alpha3/beta2 CHRNA3 CHRNB2 P32297 P17787 CHEMBL2109234 Ligand-gated ion channel 0.0604245879294
 10 / 0     
Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3 CHRNB3 CHRNA6 CHRNB2 CHRNA3 Q05901 Q15825 P17787 P32297 CHEMBL2109233 Ligand-gated ion channel 0.0604245879294
 7 / 0     
Fibroblast activation protein alpha FAP Q12884 CHEMBL4683 Protease 0.0604245879294
 39 / 0     
Serotonin 1f (5-HT1f) receptor HTR1F P30939 CHEMBL1805 Family A G protein-coupled receptor 0.0604245879294
 61 / 0     
Serine/threonine-protein kinase AKT AKT1 P31749 CHEMBL4282 Kinase 0.0604245879294
 46 / 0     
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 0.0604245879294
 41 / 0     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.0604245879294
 363 / 57     
Huntingtin HTT P42858 CHEMBL5514 Unclassified protein 0.0604245879294
 9 / 0     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0604245879294
 242 / 0     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.0604245879294
 67 / 0     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.0604245879294
 6 / 0     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.0604245879294
 74 / 0     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.0604245879294
 61 / 0     
Quinone reductase 2 NQO2 P16083 CHEMBL3959 Enzyme 0.0604245879294
 26 / 0     
Phosphodiesterase 8B PDE8B O95263 CHEMBL4408 Phosphodiesterase 0.0604245879294
 3 / 0     
Leukocyte elastase ELANE P08246 CHEMBL248 Protease 0.0604245879294
 13 / 0     
Melanocortin receptor 4 MC4R P32245 CHEMBL259 Family A G protein-coupled receptor 0.0604245879294
 16 / 0     
Beta-3 adrenergic receptor ADRB3 P13945 CHEMBL246 Family A G protein-coupled receptor 0.0604245879294
 2 / 1     
Nitric-oxide synthase, brain NOS1 P29475 CHEMBL3568 Enzyme 0.0604245879294
 88 / 0     
Serotonin 5a (5-HT5a) receptor (by homology) HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.0604245879294
 24 / 0     
Amine oxidase, copper containing AOC3 Q16853 CHEMBL3437 Enzyme 0.0604245879294
 9 / 0     
Protein kinase C theta PRKCQ Q04759 CHEMBL3920 Kinase 0.0604245879294
 74 / 0     
Leukocyte proteinase 3 (by homology) PRTN3 P24158 CHEMBL3900 Protease 0.0604245879294
 1 / 0     
Leucine-rich repeat serine/threonine-protein kinase 2 LRRK2 Q5S007 CHEMBL1075104 Kinase 0.0604245879294
 6 / 0     
Interleukin-1 receptor-associated kinase 4 IRAK4 Q9NWZ3 CHEMBL3778 Kinase 0.0604245879294
 48 / 0     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.0604245879294
 33 / 0     
Tyrosine-protein kinase TYK2 TYK2 P29597 CHEMBL3553 Kinase 0.0604245879294
 17 / 0     
Quinone reductase 1 NQO1 P15559 CHEMBL3623 Enzyme 0.0604245879294
 5 / 0     
Poly [ADP-ribose] polymerase 2 PARP2 Q9UGN5 CHEMBL5366 Enzyme 0.0604245879294
 29 / 0     
Solute carrier family 22 member 2 SLC22A2 O15244 CHEMBL1743122 Electrochemical transporter 0.0604245879294
 1 / 0     
Multidrug and toxin extrusion protein 1 SLC47A1 Q96FL8 CHEMBL1743126 Electrochemical transporter 0.0604245879294
 2 / 0     
Serotonin 3 (5-HT3) receptor HTR3B HTR3A O95264 P46098 CHEMBL2111332 Ligand-gated ion channel 0.0604245879294
 1 / 0     
Serine/threonine-protein kinase Chk1 CHEK1 O14757 CHEMBL4630 Kinase 0.0604245879294
 99 / 0     
Sodium channel protein type IV alpha subunit SCN4A P35499 CHEMBL2072 Voltage-gated ion channel 0.0
 11 / 0     
Inhibitor of nuclear factor kappa B kinase beta subunit IKBKB O14920 CHEMBL1991 Kinase 0.0
 33 / 0     
Telomerase reverse transcriptase TERT O14746 CHEMBL2916 Enzyme 0.0
 13 / 0     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0
 138 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.0
 101 / 0     
Nicotinic acetylcholine receptor alpha4/beta2/alpha5 CHRNA5 CHRNB2 CHRNA4 P30532 P17787 P43681 CHEMBL3038461 Ligand-gated ion channel 0.0
 1 / 1     
Bradykinin B2 receptor BDKRB2 P30411 CHEMBL3157 Family A G protein-coupled receptor 0.0
 6 / 0     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.0
 36 / 0     
Focal adhesion kinase 1 PTK2 Q05397 CHEMBL2695 Kinase 0.0
 2 / 0     
Serine/threonine-protein kinase PRKX PRKX P51817 CHEMBL5818 Kinase 0.0
 2 / 0     
PDZ-binding kinase PBK Q96KB5 CHEMBL4896 Kinase 0.0
 22 / 0     
Urotensin II receptor UTS2R Q9UKP6 CHEMBL3764 Family A G protein-coupled receptor 0.0
 54 / 17     
Hormone sensitive lipase LIPE Q05469 CHEMBL3590 Enzyme 0.0
 1 / 0     
Bromodomain-containing protein 4 BRD4 O60885 CHEMBL1163125 Reader 0.0
 19 / 0     
Histone acetyltransferase PCAF KAT2B Q92831 CHEMBL5500 Writer 0.0
 3 / 0     
C-C chemokine receptor type 4 CCR4 P51679 CHEMBL2414 Family A G protein-coupled receptor 0.0
 8 / 0     
Protein kinase C iota PRKCI P41743 CHEMBL2598 Kinase 0.0
 52 / 0     
Inhibitor of NF-kappa-B kinase (IKK) CHUK O15111 CHEMBL3476 Kinase 0.0
 11 / 0     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.0
 319 / 22     
Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET RET P07949 CHEMBL2041 Kinase 0.0
 15 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.