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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.0
111 / 0     
Squalene synthetase (by homology) FDFT1 P37268 CHEMBL3338 Enzyme 0.0
29 / 0     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0
260 / 0     
Beta-glucocerebrosidase GBA P04062 CHEMBL2179 Enzyme 0.0
0 / 40     
Neurokinin 1 receptor TACR1 P25103 CHEMBL249 Family A G protein-coupled receptor 0.0
70 / 0     
Vascular endothelial growth factor receptor 2 KDR P35968 CHEMBL279 Kinase 0.0
99 / 0     
Melanin-concentrating hormone receptor 1 MCHR1 Q99705 CHEMBL344 Family A G protein-coupled receptor 0.0
200 / 0     
Alpha-L-fucosidase I FUCA1 P04066 CHEMBL4176 Enzyme 0.0
0 / 21     
Neprilysin MME P08473 CHEMBL1944 Protease 0.0
0 / 20     
Melanocortin receptor 4 MC4R P32245 CHEMBL259 Family A G protein-coupled receptor 0.0
309 / 0     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.0
34 / 0     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.0
612 / 196     
Alpha-1a adrenergic receptor (by homology) ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.0
81 / 0     
Epoxide hydrolase 1 EPHX1 P07099 CHEMBL1968 Protease 0.0
0 / 37     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0
8 / 0     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.0
170 / 0     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0
268 / 0     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.0
45 / 9     
Protein kinase C beta PRKCB P05771 CHEMBL3045 Kinase 0.0
114 / 0     
Group X secretory phospholipase A2 PLA2G10 O15496 CHEMBL4342 Enzyme 0.0
0 / 2     
Monoamine oxidase A MAOA P21397 CHEMBL1951 Oxidoreductase 0.0
31 / 0     
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 0.0
39 / 0     
Neurokinin 2 receptor TACR2 P21452 CHEMBL2327 Family A G protein-coupled receptor 0.0
31 / 0     
MAP kinase ERK2 (by homology) MAPK1 P28482 CHEMBL4040 Kinase 0.0
77 / 0     
Trace amine-associated receptor 1 (by homology) TAAR1 Q96RJ0 CHEMBL5857 Family A G protein-coupled receptor 0.0
27 / 0     
Peptide N-myristoyltransferase 1 NMT1 P30419 CHEMBL2593 Enzyme 0.0
16 / 0     
Integrin alpha-IIb/beta-3 ITGA2B ITGB3 P08514 P05106 CHEMBL2093869 Membrane receptor 0.0
1 / 51     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0
106 / 0     
Tyrosine-protein kinase JAK1 JAK1 P23458 CHEMBL2835 Kinase 0.0
85 / 0     
Maternal embryonic leucine zipper kinase MELK Q14680 CHEMBL4578 Kinase 0.0
168 / 0     
Vasopressin V1a receptor AVPR1A P37288 CHEMBL1889 Family A G protein-coupled receptor 0.0
38 / 0     
FK506-binding protein 1A FKBP1A P62942 CHEMBL1902 Isomerase 0.0
0 / 2     
Oxytocin receptor (by homology) OXTR P30559 CHEMBL2049 Family A G protein-coupled receptor 0.0
18 / 0     
Metabotropic glutamate receptor 3 GRM3 Q14832 CHEMBL2888 Family C G protein-coupled receptor 0.0
0 / 1     
Metabotropic glutamate receptor 8 GRM8 O00222 CHEMBL3228 Family C G protein-coupled receptor 0.0
0 / 1     
Metabotropic glutamate receptor 6 GRM6 O15303 CHEMBL4573 Family C G protein-coupled receptor 0.0
0 / 2     
Tyrosine-protein kinase JAK2 JAK2 O60674 CHEMBL2971 Kinase 0.0
82 / 0     
Serine/threonine-protein kinase PAK 4 PAK4 O96013 CHEMBL4482 Kinase 0.0
20 / 0     
Orexin receptor 2 HCRTR2 O43614 CHEMBL4792 Family A G protein-coupled receptor 0.0
12 / 0     
Rho-associated protein kinase ROCK2 ROCK1 O75116 Q13464 CHEMBL2111459 Kinase 0.0
8 / 0     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.0
71 / 0     
Somatostatin receptor 2 (by homology) SSTR2 P30874 CHEMBL1804 Family A G protein-coupled receptor 0.0
38 / 0     
Histamine H1 receptor HRH1 P35367 CHEMBL231 Family A G protein-coupled receptor 0.0
32 / 0     
Serine/threonine-protein kinase AKT AKT1 P31749 CHEMBL4282 Kinase 0.0
335 / 0     
Baculoviral IAP repeat-containing protein 8 BIRC8 Q96P09 CHEMBL5851 Unclassified protein 0.0
3 / 0     
Androgen Receptor AR P10275 CHEMBL1871 Nuclear receptor 0.0
14 / 21     
Macrophage colony stimulating factor receptor CSF1R P07333 CHEMBL1844 Kinase 0.0
55 / 0     
Voltage-gated L-type calcium channel alpha-1S subunit CACNA1S Q13698 CHEMBL3805 Voltage-gated ion channel 0.0
8 / 0     
Glycogen synthase kinase-3 beta GSK3B P49841 CHEMBL262 Kinase 0.0
35 / 0     
Protein kinase C gamma PRKCG P05129 CHEMBL2938 Kinase 0.0
15 / 0     
Serine/threonine-protein kinase Chk1 CHEK1 O14757 CHEMBL4630 Kinase 0.0
159 / 0     
Vasopressin V2 receptor (by homology) AVPR2 P30518 CHEMBL1790 Family A G protein-coupled receptor 0.0
19 / 0     
MAP kinase-activated protein kinase 2 MAPKAPK2 P49137 CHEMBL2208 Kinase 0.0
100 / 0     
Serine/threonine-protein kinase B-raf BRAF P15056 CHEMBL5145 Kinase 0.0
34 / 0     
Cyclin-dependent kinase 2/cyclin A CDK2 CCNA1 CCNA2 P24941 P78396 P20248 CHEMBL2094128 Other cytosolic protein 0.0
14 / 0     
Orexin receptor 1 HCRTR1 O43613 CHEMBL5113 Family A G protein-coupled receptor 0.0
6 / 0     
11-beta-hydroxysteroid dehydrogenase 1 HSD11B1 P28845 CHEMBL4235 Enzyme 0.0
10 / 45     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.0
43 / 0     
Inosine-5'-monophosphate dehydrogenase 2 IMPDH2 P12268 CHEMBL2002 Oxidoreductase 0.0
2 / 0     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.0
254 / 0     
Phosphodiesterase 2A PDE2A O00408 CHEMBL2652 Phosphodiesterase 0.0
4 / 0     
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Q02750 CHEMBL3587 Kinase 0.0
19 / 0     
Phosphodiesterase 10A (by homology) PDE10A Q9Y233 CHEMBL4409 Phosphodiesterase 0.0
16 / 0     
Estradiol 17-beta-dehydrogenase 3 HSD17B3 P37058 CHEMBL4234 Enzyme 0.0
0 / 4     
Synaptic vesicular amine transporter (by homology) SLC18A2 Q05940 CHEMBL1893 Electrochemical transporter 0.0
22 / 0     
Glutamate NMDA receptor; GRIN1/GRIN2B GRIN1 GRIN2B Q05586 Q13224 CHEMBL1907603 Ligand-gated ion channel 0.0
7 / 0     
Myosin light chain kinase, smooth muscle MYLK Q15746 CHEMBL2428 Kinase 0.0
3 / 0     
Probable G-protein coupled receptor 88 GPR88 Q9GZN0 CHEMBL3399910 Family A G protein-coupled receptor 0.0
25 / 0     
Tankyrase-1 TNKS O95271 CHEMBL6164 Enzyme 0.0
10 / 0     
Dipeptidyl peptidase I CTSC P53634 CHEMBL2252 Protease 0.0
66 / 0     
C-C chemokine receptor type 4 CCR4 P51679 CHEMBL2414 Family A G protein-coupled receptor 0.0
16 / 0     
Telomerase reverse transcriptase TERT O14746 CHEMBL2916 Enzyme 0.0
6 / 0     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.0
182 / 0     
Beta-glucosidase GBA2 Q9HCG7 CHEMBL3761 Enzyme 0.0
0 / 33     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.0
24 / 0     
Tyrosine-protein kinase ITK/TSK ITK Q08881 CHEMBL2959 Kinase 0.0
16 / 0     
Glycine transporter 2 SLC6A5 Q9Y345 CHEMBL3060 Electrochemical transporter 0.0
17 / 0     
MAP kinase ERK1 (by homology) MAPK3 P27361 CHEMBL3385 Kinase 0.0
34 / 0     
Protein kinase C theta PRKCQ Q04759 CHEMBL3920 Kinase 0.0
96 / 0     
DNA (cytosine-5)-methyltransferase 1 (by homology) DNMT1 P26358 CHEMBL1993 Writer 0.0
3 / 0     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.0
251 / 3     
Carbonic anhydrase II CA2 P00918 CHEMBL205 Lyase 0.0
22 / 0     
Urotensin II receptor UTS2R Q9UKP6 CHEMBL3764 Family A G protein-coupled receptor 0.0
25 / 0     
Ketohexokinase KHK P50053 CHEMBL1275212 Enzyme 0.0
15 / 0     
Baculoviral IAP repeat-containing protein 3 BIRC3 Q13489 CHEMBL5335 Enzyme 0.0
11 / 0     
Dopamine D1 receptor DRD1 P21728 CHEMBL2056 Family A G protein-coupled receptor 0.0
59 / 0     
3-phosphoinositide dependent protein kinase-1 PDPK1 O15530 CHEMBL2534 Kinase 0.0
22 / 0     
Ribosomal protein S6 kinase 1 RPS6KB1 P23443 CHEMBL4501 Kinase 0.0
55 / 0     
Ghrelin receptor GHSR Q92847 CHEMBL4616 Family A G protein-coupled receptor 0.0
44 / 0     
Poly [ADP-ribose] polymerase 2 PARP2 Q9UGN5 CHEMBL5366 Enzyme 0.0
26 / 0     
Prostanoid EP4 receptor PTGER4 P35408 CHEMBL1836 Family A G protein-coupled receptor 0.0
0 / 4     
Prostanoid EP3 receptor PTGER3 P43115 CHEMBL3710 Family A G protein-coupled receptor 0.0
0 / 3     
Tissue-type plasminogen activator PLAT P00750 CHEMBL1873 Protease 0.0
7 / 0     
C-X-C chemokine receptor type 4 CXCR4 P61073 CHEMBL2107 Family A G protein-coupled receptor 0.0
24 / 0     
C-X-C chemokine receptor type 3 CXCR3 P49682 CHEMBL4441 Family A G protein-coupled receptor 0.0
15 / 0     
Lysine-specific histone demethylase 1 KDM1A O60341 CHEMBL6136 Eraser 0.0
33 / 0     
Protein farnesyltransferase FNTA FNTB P49354 P49356 CHEMBL2094108 Enzyme 0.0
25 / 0     
Tyrosine-protein kinase JAK3 JAK3 P52333 CHEMBL2148 Kinase 0.0
44 / 0     
Protein kinase C iota PRKCI P41743 CHEMBL2598 Kinase 0.0
24 / 0     
Cyclin-dependent kinase 2 CDK2 P24941 CHEMBL301 Kinase 0.0
50 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.