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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.398734149538
61 / 11     
Neuronal acetylcholine receptor; alpha3/beta4 CHRNA3 CHRNB4 P32297 P30926 CHEMBL1907594 Ligand-gated ion channel 0.389993007963
42 / 21     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.164442067635
72 / 202     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.138495281987
77 / 137     
Estrogen receptor beta ESR2 Q92731 CHEMBL242 Nuclear receptor 0.0864426933852
1 / 3     
Alpha-1a adrenergic receptor ADRA1A P35348 CHEMBL229 Family A G protein-coupled receptor 0.0777583259988
21 / 93     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.0777583259988
19 / 87     
Serotonin 1b (5-HT1b) receptor (by homology) HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.0690974435253
43 / 22     
Muscarinic acetylcholine receptor M1 CHRM1 P11229 CHEMBL216 Family A G protein-coupled receptor 0.0690974435253
55 / 29     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0690974435253
25 / 37     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.0690974435253
16 / 89     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.0690974435253
22 / 5     
Histamine H3 receptor HRH3 Q9Y5N1 CHEMBL264 Family A G protein-coupled receptor 0.0604245879294
22 / 246     
Muscarinic acetylcholine receptor M2 CHRM2 P08172 CHEMBL211 Family A G protein-coupled receptor 0.0604245879294
38 / 31     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.0604245879294
113 / 110     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0604245879294
48 / 65     
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0604245879294
117 / 145     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.0604245879294
117 / 92     
Neuronal acetylcholine receptor protein alpha-4 subunit CHRNA4 P43681 CHEMBL1882 Ligand-gated ion channel 0.0604245879294
15 / 0     
Melatonin receptor 1A MTNR1A P48039 CHEMBL1945 Family A G protein-coupled receptor 0.0604245879294
2 / 9     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0604245879294
7 / 9     
Amine oxidase, copper containing AOC3 Q16853 CHEMBL3437 Enzyme 0.0604245879294
2 / 0     
Alpha-2a adrenergic receptor ADRA2A P08913 CHEMBL1867 Family A G protein-coupled receptor 0.0604245879294
3 / 9     
Squalene synthetase (by homology) FDFT1 P37268 CHEMBL3338 Enzyme 0.0604245879294
0 / 8     
Serotonin 2c (5-HT2c) receptor HTR2C P28335 CHEMBL225 Family A G protein-coupled receptor 0.0604245879294
56 / 5     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0604245879294
14 / 27     
Leukotriene A4 hydrolase LTA4H P09960 CHEMBL4618 Protease 0.0604245879294
7 / 67     
Acetylcholine receptor; alpha1/beta1/delta/gamma CHRNB1 CHRNA1 CHRNG CHRND P11230 P02708 P07510 Q07001 CHEMBL1907588 Ligand-gated ion channel 0.0604245879294
2 / 0     
Alpha-2b adrenergic receptor ADRA2B P18089 CHEMBL1942 Family A G protein-coupled receptor 0.0
1 / 8     
Serotonin 2b (5-HT2b) receptor HTR2B P41595 CHEMBL1833 Family A G protein-coupled receptor 0.0
36 / 5     
Serotonin 2a (5-HT2a) receptor HTR2A P28223 CHEMBL224 Family A G protein-coupled receptor 0.0
91 / 12     
Thrombin F2 P00734 CHEMBL204 Protease 0.0
0 / 3     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0
17 / 5     
Interleukin-1 receptor-associated kinase 4 IRAK4 Q9NWZ3 CHEMBL3778 Kinase 0.0
2 / 0     
Serotonin 1f (5-HT1f) receptor HTR1F P30939 CHEMBL1805 Family A G protein-coupled receptor 0.0
4 / 0     
Toll-like receptor (TLR7/TLR9) TLR9 Q9NR96 CHEMBL5804 Toll-like and Il-1 receptors 0.0
1 / 0     
Serotonin 1e (5-HT1e) receptor HTR1E P28566 CHEMBL2182 Family A G protein-coupled receptor 0.0
2 / 0     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.0
1 / 0     
Serotonin 5a (5-HT5a) receptor (by homology) HTR5A P47898 CHEMBL3426 Family A G protein-coupled receptor 0.0
7 / 0     
Protein arginine N-methyltransferase 6 PRMT6 Q96LA8 CHEMBL1275221 Writer 0.0
2 / 0     
Histone-arginine methyltransferase CARM1 CARM1 Q86X55 CHEMBL5406 Writer 0.0
1 / 0     
Dopamine D4 receptor DRD4 P21917 CHEMBL219 Family A G protein-coupled receptor 0.0
12 / 111     
c-Jun N-terminal kinase 1 MAPK8 P45983 CHEMBL2276 Kinase 0.0
2 / 0     
Dihydrofolate reductase DHFR P00374 CHEMBL202 Oxidoreductase 0.0
12 / 0     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0
7 / 0     
Serine/threonine-protein kinase PIM2 PIM2 Q9P1W9 CHEMBL4523 Kinase 0.0
6 / 0     
Histamine H4 receptor HRH4 Q9H3N8 CHEMBL3759 Family A G protein-coupled receptor 0.0
8 / 0     
Adrenergic receptor beta ADRB2 P07550 CHEMBL210 Family A G protein-coupled receptor 0.0
0 / 38     
Beta-3 adrenergic receptor ADRB3 P13945 CHEMBL246 Family A G protein-coupled receptor 0.0
0 / 11     
Inhibitor of apoptosis protein 3 XIAP P98170 CHEMBL4198 Other cytosolic protein 0.0
3 / 0     
Baculoviral IAP repeat-containing protein 2 BIRC2 Q13490 CHEMBL5462 Enzyme 0.0
1 / 0     
Glycogen synthase kinase-3 beta GSK3B P49841 CHEMBL262 Kinase 0.0
2 / 0     
Metastin receptor KISS1R Q969F8 CHEMBL5413 Family A G protein-coupled receptor 0.0
3 / 0     
Telomerase reverse transcriptase TERT O14746 CHEMBL2916 Enzyme 0.0
2 / 0     
Sodium channel protein type IV alpha subunit SCN4A P35499 CHEMBL2072 Voltage-gated ion channel 0.0
3 / 0     
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 P32297 CHEMBL3068 Ligand-gated ion channel 0.0
1 / 0     
Ceramide glucosyltransferase UGCG Q16739 CHEMBL2063 Transferase 0.0
0 / 22     
Beta-glucocerebrosidase GBA P04062 CHEMBL2179 Enzyme 0.0
0 / 20     
Beta-glucosidase GBA2 Q9HCG7 CHEMBL3761 Enzyme 0.0
0 / 24     
Monoamine oxidase A MAOA P21397 CHEMBL1951 Oxidoreductase 0.0
12 / 2     
Monoamine oxidase B MAOB P27338 CHEMBL2039 Oxidoreductase 0.0
10 / 3     
c-Jun N-terminal kinase 2 MAPK9 P45984 CHEMBL4179 Kinase 0.0
1 / 0     
Trace amine-associated receptor 1 (by homology) TAAR1 Q96RJ0 CHEMBL5857 Family A G protein-coupled receptor 0.0
1 / 0     
Protein arginine N-methyltransferase 8 PRMT8 Q9NR22 CHEMBL3108648 Writer 0.0
1 / 0     
Protein-arginine N-methyltransferase 1 PRMT1 Q99873 CHEMBL5524 Writer 0.0
1 / 0     
Epidermal growth factor receptor erbB1 EGFR P00533 CHEMBL203 Kinase 0.0
1 / 0     
Bromodomain adjacent to zinc finger domain protein 2B BAZ2B Q9UIF8 CHEMBL1741220 Reader 0.0
3 / 0     
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Q9UIF9 CHEMBL3108642 Reader 0.0
4 / 0     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0
3 / 0     
Protein kinase C theta PRKCQ Q04759 CHEMBL3920 Kinase 0.0
1 / 0     
Solute carrier family 22 member 2 SLC22A2 O15244 CHEMBL1743122 Electrochemical transporter 0.0
0 / 1     
Potassium channel subfamily K member 2 KCNK2 O95069 CHEMBL2321615 Voltage-gated ion channel 0.0
0 / 1     
Potassium channel subfamily K member 10 KCNK10 P57789 CHEMBL2331041 Voltage-gated ion channel 0.0
0 / 1     
Leucine aminopeptidase LAP3 P28838 CHEMBL3965 Protease 0.0
1 / 0     
Phosphodiesterase 10A PDE10A Q9Y233 CHEMBL4409 Phosphodiesterase 0.0
3 / 0     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.0
20 / 1     
Angiotensin-converting enzyme (by homology) ACE P12821 CHEMBL1808 Protease 0.0
0 / 2     
Serine/threonine-protein kinase Chk2 CHEK2 O96017 CHEMBL2527 Kinase 0.0
1 / 0     
Beta-1 adrenergic receptor ADRB1 P08588 CHEMBL213 Family A G protein-coupled receptor 0.0
3 / 40     
Serotonin 4 (5-HT4) receptor HTR4 Q13639 CHEMBL1875 Family A G protein-coupled receptor 0.0
3 / 0     
Adenosine A2a receptor ADORA2A P29274 CHEMBL251 Family A G protein-coupled receptor 0.0
1 / 0     
Lysine-specific histone demethylase 1 KDM1A O60341 CHEMBL6136 Eraser 0.0
5 / 0     
Somatostatin receptor 4 SSTR4 P31391 CHEMBL1853 Family A G protein-coupled receptor 0.0
1 / 0     
Somatostatin receptor 1 SSTR1 P30872 CHEMBL1917 Family A G protein-coupled receptor 0.0
1 / 0     
Delta opioid receptor OPRD1 P41143 CHEMBL236 Family A G protein-coupled receptor 0.0
24 / 60     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.0
46 / 23     
11-beta-hydroxysteroid dehydrogenase 2 (by homology) HSD11B2 P80365 CHEMBL3746 Enzyme 0.0
0 / 5     
Dual specificity mitogen-activated protein kinase kinase 1 MAP2K1 Q02750 CHEMBL3587 Kinase 0.0
1 / 0     
HERG KCNH2 Q12809 CHEMBL240 Voltage-gated ion channel 0.0
11 / 55     
Matrix metalloproteinase 2 MMP2 P08253 CHEMBL333 Protease 0.0
2 / 0     
PDZ-binding kinase PBK Q96KB5 CHEMBL4896 Kinase 0.0
1 / 0     
Arachidonate 5-lipoxygenase ALOX5 P09917 CHEMBL215 Oxidoreductase 0.0
0 / 10     
Sodium channel protein type II alpha subunit SCN2A Q99250 CHEMBL4187 Voltage-gated ion channel 0.0
1 / 0     
Cyclin-dependent kinase 2/cyclin E1 CCNE1 CDK2 P24864 P24941 CHEMBL1907605 Kinase 0.0
1 / 0     
Histone acetyltransferase PCAF KAT2B Q92831 CHEMBL5500 Writer 0.0
2 / 0     
Carnitine O-palmitoyltransferase 1, muscle isoform (by homology) CPT1B Q92523 CHEMBL2216739 Group translocator 0.0
1 / 0     
Cyclin-dependent kinase 9 CDK9 P50750 CHEMBL3116 Kinase 0.0
1 / 0     
Protein tyrosine phosphatase receptor type C-associated protein PTPRCAP Q14761 CHEMBL4806 Enzyme 0.0
1 / 0     
FK506-binding protein 1A FKBP1A P62942 CHEMBL1902 Isomerase 0.0
0 / 3     
Hepatocyte growth factor receptor MET P08581 CHEMBL3717 Kinase 0.0
1 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.