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Query Molecule
Target Classes
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Export results:
Target Common name Uniprot ID ChEMBL ID Target Class Probability* Known actives (3D/2D)
Serotonin transporter SLC6A4 P31645 CHEMBL228 Electrochemical transporter 0.0721804396226
1064 / 113     
Dopamine transporter SLC6A3 Q01959 CHEMBL238 Electrochemical transporter 0.0721804396226
850 / 131     
Norepinephrine transporter SLC6A2 P23975 CHEMBL222 Electrochemical transporter 0.0619149311119
602 / 68     
Neuronal acetylcholine receptor; alpha4/beta2 CHRNA4 CHRNB2 P43681 P17787 CHEMBL1907589 Ligand-gated ion channel 0.0312265582077
138 / 0     
Neuronal acetylcholine receptor protein alpha-7 subunit CHRNA7 P36544 CHEMBL2492 Ligand-gated ion channel 0.0312265582077
105 / 0     
Neuronal acetylcholine receptor; alpha3/beta2 CHRNA3 CHRNB2 P32297 P17787 CHEMBL2109234 Ligand-gated ion channel 0.0312265582077
7 / 0     
Adrenergic receptor alpha-2 ADRA2C P18825 CHEMBL1916 Family A G protein-coupled receptor 0.0312265582077
15 / 0     
Cytochrome P450 2D6 CYP2D6 P10635 CHEMBL289 Cytochrome P450 0.0312265582077
4 / 0     
Cytochrome P450 2C19 CYP2C19 P33261 CHEMBL3622 Cytochrome P450 0.0312265582077
2 / 0     
Neuronal acetylcholine receptor protein alpha-4 subunit CHRNA4 P43681 CHEMBL1882 Ligand-gated ion channel 0.0312265582077
36 / 0     
Alpha-1d adrenergic receptor ADRA1D P25100 CHEMBL223 Family A G protein-coupled receptor 0.0312265582077
4 / 0     
Alpha-1b adrenergic receptor ADRA1B P35368 CHEMBL232 Family A G protein-coupled receptor 0.0312265582077
5 / 0     
Tyrosine- and threonine-specific cdc2-inhibitory kinase PKMYT1 Q99640 CHEMBL3984 Kinase 0.0312265582077
1 / 0     
Serine/threonine-protein kinase Chk1 CHEK1 O14757 CHEMBL4630 Kinase 0.0312265582077
9 / 0     
Sigma opioid receptor SIGMAR1 Q99720 CHEMBL287 Membrane receptor 0.0312265582077
155 / 83     
Serotonin 1b (5-HT1b) receptor HTR1B P28222 CHEMBL1898 Family A G protein-coupled receptor 0.0312265582077
55 / 0     
Serotonin 1d (5-HT1d) receptor HTR1D P28221 CHEMBL1983 Family A G protein-coupled receptor 0.0312265582077
40 / 0     
Nitric-oxide synthase, brain NOS1 P29475 CHEMBL3568 Enzyme 0.0312265582077
32 / 0     
Nitric oxide synthase, inducible NOS2 P35228 CHEMBL4481 Enzyme 0.0312265582077
29 / 0     
Dipeptidyl peptidase IV DPP4 P27487 CHEMBL284 Protease 0.0312265582077
305 / 0     
Cytochrome P450 11B2 CYP11B2 P19099 CHEMBL2722 Cytochrome P450 0.0312265582077
1 / 0     
Serotonin 1a (5-HT1a) receptor HTR1A P08908 CHEMBL214 Family A G protein-coupled receptor 0.0312265582077
109 / 0     
Dopamine D2 receptor DRD2 P14416 CHEMBL217 Family A G protein-coupled receptor 0.0312265582077
343 / 34     
Phenylethanolamine N-methyltransferase PNMT P11086 CHEMBL4617 Enzyme 0.0312265582077
25 / 0     
Neuronal acetylcholine receptor; alpha4/beta4 CHRNB4 CHRNA4 P30926 P43681 CHEMBL1907591 Ligand-gated ion channel 0.0312265582077
3 / 0     
Neuronal acetylcholine receptor; alpha2/beta4 CHRNB4 CHRNA2 P30926 Q15822 CHEMBL2109230 Ligand-gated ion channel 0.0312265582077
2 / 0     
Epoxide hydratase EPHX2 P34913 CHEMBL2409 Protease 0.0312265582077
2 / 0     
Acetylcholine receptor protein alpha chain CHRNA1 P02708 CHEMBL4808 Ligand-gated ion channel 0.0312265582077
2 / 0     
Serotonin 6 (5-HT6) receptor HTR6 P50406 CHEMBL3371 Family A G protein-coupled receptor 0.0312265582077
186 / 0     
Acetylcholine receptor; alpha1/beta1/delta/gamma CHRNB1 CHRNA1 CHRNG CHRND P11230 P02708 P07510 Q07001 CHEMBL1907588 Ligand-gated ion channel 0.0
8 / 0     
Lysosomal Pro-X carboxypeptidase PRCP P42785 CHEMBL2335 Protease 0.0
3 / 0     
Serotonin 7 (5-HT7) receptor HTR7 P34969 CHEMBL3155 Family A G protein-coupled receptor 0.0
41 / 0     
Muscarinic acetylcholine receptor M4 CHRM4 P08173 CHEMBL1821 Family A G protein-coupled receptor 0.0
20 / 0     
Muscarinic acetylcholine receptor M3 CHRM3 P20309 CHEMBL245 Family A G protein-coupled receptor 0.0
34 / 0     
Metabotropic glutamate receptor 3 GRM3 Q14832 CHEMBL2888 Family C G protein-coupled receptor 0.0
2 / 0     
Kappa Opioid receptor OPRK1 P41145 CHEMBL237 Family A G protein-coupled receptor 0.0
35 / 16     
Dipeptidyl peptidase VIII DPP8 Q6V1X1 CHEMBL4657 Protease 0.0
54 / 0     
Dipeptidyl peptidase IX DPP9 Q86TI2 CHEMBL4793 Protease 0.0
44 / 0     
Neuronal acetylcholine receptor; alpha3/alpha6/beta2/beta3 CHRNB3 CHRNA6 CHRNB2 CHRNA3 Q05901 Q15825 P17787 P32297 CHEMBL2109233 Ligand-gated ion channel 0.0
4 / 0     
Adrenergic receptor beta ADRB2 P07550 CHEMBL210 Family A G protein-coupled receptor 0.0
6 / 0     
Myeloperoxidase MPO P05164 CHEMBL2439 Enzyme 0.0
21 / 0     
Lethal(3)malignant brain tumor-like protein 3 L3MBTL3 Q96JM7 CHEMBL1287623 Reader 0.0
6 / 0     
Estrogen receptor beta ESR2 Q92731 CHEMBL242 Nuclear receptor 0.0
2 / 0     
Butyrylcholinesterase BCHE P06276 CHEMBL1914 Hydrolase 0.0
19 / 0     
Serine/threonine-protein kinase PIM1 PIM1 P11309 CHEMBL2147 Kinase 0.0
26 / 0     
Dipeptidyl peptidase II DPP7 Q9UHL4 CHEMBL3976 Protease 0.0
41 / 0     
Serotonin 3a (5-HT3a) receptor HTR3A P46098 CHEMBL1899 Ligand-gated ion channel 0.0
25 / 0     
Histone acetyltransferase PCAF KAT2B Q92831 CHEMBL5500 Writer 0.0
6 / 0     
Carbonic anhydrase II CA2 P00918 CHEMBL205 Lyase 0.0
35 / 0     
Myosin light chain kinase, smooth muscle MYLK Q15746 CHEMBL2428 Kinase 0.0
3 / 0     
Carbonic anhydrase I CA1 P00915 CHEMBL261 Lyase 0.0
8 / 0     
Poly [ADP-ribose] polymerase-1 PARP1 P09874 CHEMBL3105 Enzyme 0.0
17 / 0     
Phospholipase D1 PLD1 Q13393 CHEMBL2536 Hydrolase 0.0
1 / 0     
Hormone sensitive lipase LIPE Q05469 CHEMBL3590 Enzyme 0.0
1 / 0     
MAP kinase p38 alpha MAPK14 Q16539 CHEMBL260 Kinase 0.0
4 / 0     
Leukotriene A4 hydrolase LTA4H P09960 CHEMBL4618 Protease 0.0
7 / 0     
Histamine H2 receptor HRH2 P25021 CHEMBL1941 Family A G protein-coupled receptor 0.0
10 / 0     
Transient receptor potential cation channel subfamily V member 4 TRPV4 Q9HBA0 CHEMBL3119 Voltage-gated ion channel 0.0
1 / 0     
PDZ-binding kinase PBK Q96KB5 CHEMBL4896 Kinase 0.0
1 / 0     
Melatonin receptor 1A MTNR1A P48039 CHEMBL1945 Family A G protein-coupled receptor 0.0
0 / 8     
Fibroblast activation protein alpha FAP Q12884 CHEMBL4683 Protease 0.0
17 / 0     
Neuronal acetylcholine receptor subunit alpha-3 CHRNA3 P32297 CHEMBL3068 Ligand-gated ion channel 0.0
8 / 0     
Muscarinic acetylcholine receptor M5 CHRM5 P08912 CHEMBL2035 Family A G protein-coupled receptor 0.0
13 / 0     
Nitric-oxide synthase, endothelial NOS3 P29474 CHEMBL4803 Enzyme 0.0
6 / 0     
Adenosine A3 receptor ADORA3 P0DMS8 CHEMBL256 Family A G protein-coupled receptor 0.0
1 / 0     
MBT domain-containing protein 1 MBTD1 Q05BQ5 CHEMBL1287625 Reader 0.0
1 / 0     
Carbonic anhydrase XII CA12 O43570 CHEMBL3242 Lyase 0.0
4 / 0     
Carbonic anhydrase IX CA9 Q16790 CHEMBL3594 Lyase 0.0
5 / 0     
GABA-A receptor; alpha-3/beta-3/gamma-2 GABRB3 GABRA3 GABRG2 P28472 P34903 P18507 CHEMBL2094120 Ligand-gated ion channel 0.0
2 / 0     
GABA-A receptor; alpha-1/beta-3/gamma-2 GABRB3 GABRG2 GABRA1 P28472 P18507 P14867 CHEMBL2094121 Ligand-gated ion channel 0.0
2 / 0     
GABA-A receptor; alpha-5/beta-3/gamma-2 GABRB3 GABRG2 GABRA5 P28472 P18507 P31644 CHEMBL2094122 Ligand-gated ion channel 0.0
2 / 0     
GABA-A receptor; alpha-2/beta-3/gamma-2 GABRA2 GABRB3 GABRG2 P47869 P28472 P18507 CHEMBL2094130 Ligand-gated ion channel 0.0
2 / 0     
Gamma-secretase PSEN2 PSENEN NCSTN APH1A PSEN1 APH1B P49810 Q9NZ42 Q92542 Q96BI3 P49768 Q8WW43 CHEMBL2094135 Protease 0.0
2 / 0     
Protein tyrosine kinase 2 beta PTK2B Q14289 CHEMBL5469 Kinase 0.0
2 / 0     
Nociceptin receptor OPRL1 P41146 CHEMBL2014 Family A G protein-coupled receptor 0.0
17 / 0     
Sodium channel protein type IV alpha subunit SCN4A P35499 CHEMBL2072 Voltage-gated ion channel 0.0
2 / 0     
Progesterone receptor PGR P06401 CHEMBL208 Nuclear receptor 0.0
6 / 0     
Carbonic anhydrase IV CA4 P22748 CHEMBL3729 Lyase 0.0
2 / 0     
Serine/threonine-protein kinase AKT2 AKT2 P31751 CHEMBL2431 Kinase 0.0
21 / 0     
Multidrug resistance-associated protein 1 ABCC1 P33527 CHEMBL3004 Primary active transporter 0.0
3 / 0     
ATP-binding cassette sub-family G member 2 ABCG2 Q9UNQ0 CHEMBL5393 Primary active transporter 0.0
1 / 0     
Metastin receptor KISS1R Q969F8 CHEMBL5413 Family A G protein-coupled receptor 0.0
5 / 0     
Proteinase activated receptor 4 F2RL3 Q96RI0 CHEMBL4691 Family A G protein-coupled receptor 0.0
2 / 0     
Bromodomain adjacent to zinc finger domain protein 2A BAZ2A Q9UIF9 CHEMBL3108642 Reader 0.0
1 / 0     
Aminopeptidase A ENPEP Q07075 CHEMBL3439 Protease 0.0
1 / 0     
Histamine N-methyltransferase (by homology) HNMT P50135 CHEMBL2190 Enzyme 0.0
5 / 0     
Nuclear receptor subfamily 1 group D member 1 NR1D1 P20393 CHEMBL1961783 Nuclear receptor 0.0
4 / 0     
Mu opioid receptor OPRM1 P35372 CHEMBL233 Family A G protein-coupled receptor 0.0
44 / 22     
Rho-associated protein kinase 1 ROCK1 Q13464 CHEMBL3231 Kinase 0.0
15 / 0     
Serine/threonine-protein kinase AKT AKT1 P31749 CHEMBL4282 Kinase 0.0
13 / 0     
Beta-1 adrenergic receptor ADRB1 P08588 CHEMBL213 Family A G protein-coupled receptor 0.0
4 / 0     
Dopamine D3 receptor DRD3 P35462 CHEMBL234 Family A G protein-coupled receptor 0.0
152 / 12     
Heat shock protein 75 kDa, mitochondrial TRAP1 Q12931 CHEMBL1075132 Other cytosolic protein 0.0
2 / 0     
Endoplasmin HSP90B1 P14625 CHEMBL1075323 Other membrane protein 0.0
5 / 0     
Diamine oxidase AOC1 P19801 CHEMBL2118 Enzyme 0.0
5 / 0     
Cathepsin S CTSS P25774 CHEMBL2954 Protease 0.0
3 / 0     
Dipeptidyl peptidase I CTSC P53634 CHEMBL2252 Protease 0.0
11 / 0     
Glycogen synthase kinase-3 beta GSK3B P49841 CHEMBL262 Kinase 0.0
5 / 0     
Rho-associated protein kinase 2 ROCK2 O75116 CHEMBL2973 Kinase 0.0
17 / 0     
Choline kinase alpha CHKA P35790 CHEMBL3117 Enzyme 0.0
1 / 0     

*Probability for the query molecule - assumed as bioactive - to have this protein as target.